Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Kota V Ramana"'
Autor:
Umesh C S Yadav, Amarjit S Naura, Leopoldo Aguilera-Aguirre, Istvan Boldogh, Hamid A Boulares, William J Calhoun, Kota V Ramana, Satish K Srivastava
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57442 (2013)
Long-term and unresolved airway inflammation and airway remodeling, characteristic features of chronic asthma, if not treated could lead to permanent structural changes in the airways. Aldose reductase (AR), an aldo-sugar and lipid aldehyde metaboliz
Externí odkaz:
https://doaj.org/article/5b4926be28bd441c81554e42fd3225b6
Autor:
Umesh C S Yadav, Leopoldo Aguilera-Aguirre, Kota V Ramana, Istvan Boldogh, Satish K Srivastava
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14440 (2010)
Goblet cell metaplasia that causes mucus hypersecretion and obstruction in the airway lumen could be life threatening in asthma and chronic obstructive pulmonary disease patients. Inflammatory cytokines such as IL-13 mediate the transformation of air
Externí odkaz:
https://doaj.org/article/4bfb322bc00041ceb709b13480ce201d
Autor:
Umesh C S Yadav, Kota V Ramana, Leopoldo Aguilera-Aguirre, Istvan Boldogh, Hamid A Boulares, Satish K Srivastava
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6535 (2009)
The bronchial asthma, a clinical complication of persistent inflammation of the airway and subsequent airway hyper-responsiveness, is a leading cause of morbidity and mortality in critically ill patients. Several studies have shown that oxidative str
Externí odkaz:
https://doaj.org/article/0768bf80cbe044efa09ade9ec0bce648
Publikováno v:
Future Medicinal Chemistry. 14:809-826
Benfotiamine (S-benzoylthiamine-O-monophosphate), a unique, lipid-soluble derivative of thiamine, is the most potent allithiamine found in roasted garlic, as well as in other herbs of the genus Allium. In addition to potent antioxidative properties,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57744414c04b6504820faa447be0d88d
https://doi.org/10.4155/fmc-2022-0040
https://doi.org/10.4155/fmc-2022-0040
Supplementary Figure Legend from Aldose Reductase Regulates Growth Factor-Induced Cyclooxygenase-2 Expression and Prostaglandin E2 Production in Human Colon Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8434b1e42aab3cd988f7a101441ddf66
https://doi.org/10.1158/0008-5472.22366461
https://doi.org/10.1158/0008-5472.22366461
Supplementary Figure 1 from Aldose Reductase Regulates Growth Factor-Induced Cyclooxygenase-2 Expression and Prostaglandin E2 Production in Human Colon Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::712270fbebb4d10436c5991da0274a21
https://doi.org/10.1158/0008-5472.22366464.v1
https://doi.org/10.1158/0008-5472.22366464.v1
Inhibition of prostaglandin E2 (PGE2) and cyclooxygenase (COX)-2 by nonsteroidal anti-inflammatory drugs reduces the progression of colon cancer. Inhibition of aldose reductase (AR; EC. 1.1.1.21.) by sorbinil or by antisense ablation prevented fibrob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66129d241e707ab34785e0d0706c73b1
https://doi.org/10.1158/0008-5472.c.6495147.v1
https://doi.org/10.1158/0008-5472.c.6495147.v1
Autor:
Kota V Ramana, Myia Aiges
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 23
Abstract: Coronavirus disease-19 (COVID-19), a serious pandemic due to the SARS-CoV-2 virus infection, caused significant lockdowns, healthcare shortages, and deaths worldwide. The infection leads to an uncontrolled systemic inflammatory response cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::908c30aad0cf83978cb2b5b3d4483db9
https://doi.org/10.2174/1389557523666230324081713
https://doi.org/10.2174/1389557523666230324081713
Autor:
Kota V. Ramana, Trevor J. Plowman, Mujtaba H. Shah, Emely Fernandez, Hannah Christensen, Myia Aiges
Publikováno v:
Current Molecular Medicine. 23
Abstract: Increased hyperglycemia due to uncontrolled diabetes is the major cause of secondary diabetic complications such as retinopathy, neuropathy, nephropathy, and cardiovascular diseases. Although it is well known that increased oxidative stress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7afdc8144bc34a20eb3497c5878aa893
https://doi.org/10.2174/1566524023666220922114701
https://doi.org/10.2174/1566524023666220922114701
Autor:
Himangshu Sonowal, Kota V. Ramana
Publikováno v:
Current Medicinal Chemistry. 28:3683-3712
Aldose Reductase (AR) is an enzyme that converts glucose to sorbitol during the polyol pathway of glucose metabolism. AR has been shown to be involved in the development of secondary diabetic complications due to its involvement in causing osmotic as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c51265cb8396640110a3f3374c824f25
https://doi.org/10.2174/0929867327666201027152737
https://doi.org/10.2174/0929867327666201027152737