Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Kota, Yano"'
Autor:
Kento Takeuchi, Kanji Yamaguchi, Yusuke Takahashi, Kota Yano, Shinya Okishio, Hiroshi Ishiba, Nozomi Tochiki, Seita Kataoka, Hideki Fujii, Naoto Iwai, Yuya Seko, Atsushi Umemura, Michihisa Moriguchi, Takeshi Okanoue, Yoshito Itoh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract GDF15 and FGF21, stress-responsive cytokines primarily secreted from the liver, are promising therapeutic targets for metabolic dysfunction-associated steatotic liver disease (MASLD). However, the interaction between GDF15 and FGF21 remains
Externí odkaz:
https://doaj.org/article/df294e94fab24a5399ce4312726c6372
Autor:
Rintaro Moroi, Kota Yano, Kunio Tarasawa, Yusuke Shimoyama, Takeo Naito, Hisashi Shiga, Shin Hamada, Yoichi Kakuta, Kiyohide Fushimi, Kenji Fujimori, Yoshitaka Kinouchi, Atsushi Masamune
Publikováno v:
Inflammatory Intestinal Diseases, Pp 1-8 (2023)
Introoduction: Primary sclerosing cholangitis (PSC) is a rare disease, especially in Asian countries. PSC often develops during ulcerative colitis (UC). Little is known about the severity of PSC in patients with UC. Thus, this study aimed to investig
Externí odkaz:
https://doaj.org/article/0c0de4a457de48cb837c28f562d38625
Autor:
Yuya Seko, Kanji Yamaguchi, Kota Yano, Yusuke Takahashi, Kento Takeuchi, Seita Kataoka, Michihisa Moriguchi, Yoshito Itoh
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Both genetic and metabolic factors influence the pathology of nonalcoholic fatty liver disease (NAFLD). The aim of this retrospective study was to evaluate the impact of these factors at each stage of disease. We analysed the impact of obesi
Externí odkaz:
https://doaj.org/article/c92c56fe6b484f79af8b4c66263b8e28
Autor:
Kota Yano, Rintaro Moroi, Hisashi Shiga, Kunio Tarasawa, Yusuke Shimoyama, Masatake Kuroha, Shin Hamada, Yoichi Kakuta, Kiyohide Fushimi, Kenji Fujimori, Yoshitaka Kinouchi, Atsushi Masamune
Publikováno v:
JGH Open, Vol 6, Iss 1, Pp 50-56 (2022)
Abstract Aims Primary sclerosing cholangitis (PSC) is a relatively common complication of ulcerative colitis (UC). Only a few studies have investigated the impact of PSC on the clinical course of UC, and their conclusions are contradictory. Therefore
Externí odkaz:
https://doaj.org/article/0b35708889a04822810589a0ca3cdd71
Autor:
Rintaro Moroi, Hisashi Shiga, Kunio Tarasawa, Kota Yano, Yusuke Shimoyama, Masatake Kuroha, Yoichi Kakuta, Kiyohide Fushimi, Kenji Fujimori, Yoshitaka Kinouchi, Atsushi Masamune
Publikováno v:
JGH Open, Vol 5, Iss 8, Pp 842-848 (2021)
Abstract Background and Aim The number of elderly patients with ulcerative colitis (UC) is increasing worldwide. The clinical practice of associated treatment is still unclear. Therefore, we aimed to analyze clinical treatment realities and mortality
Externí odkaz:
https://doaj.org/article/c40c504d5651410c8a56656973f7892a
Autor:
Keiichiro Okuda, Atsushi Umemura, Seita Kataoka, Kota Yano, Aya Takahashi, Shinya Okishio, Hiroyoshi Taketani, Yuya Seko, Taichiro Nishikawa, Kanji Yamaguchi, Michihisa Moriguchi, Hayato Nakagawa, Yu Liu, Yasuhide Mitsumoto, Yoshihiro Kanbara, Toshihide Shima, Takeshi Okanoue, Yoshito Itoh
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer. HCC cells consume large amounts of glutamine to survive, but can adapt to glutamine depletion in the presence of an exogenous asparagine. L-asparaginase (ASNase) converts
Externí odkaz:
https://doaj.org/article/51f700cc3d644c598a99a775e3d1e527
Autor:
Masashi Kawamura, Tomoyuki Koike, Yohei Ogata, Ryotaro Matsumoto, Kota Yano, Takashi Hiratsuka, Hideaki Ohyama, Isao Sato, Kimiko Kayada, Suguo Suzuki, Satsuki Hiratsuka, Yumiko Watanabe
Publikováno v:
Diagnostics, Vol 12, Iss 12, p 3012 (2022)
Several endoscopic findings obtained by magnifying image-enhanced endoscopy (IEE) are reportedly correlated with gastric intestinal metaplasia (IM); however, the differences between magnifying and nonmagnifying IEE for the diagnosis of gastric IM rem
Externí odkaz:
https://doaj.org/article/684aeb241a4147b3aaf35cb2b967c2ec
Autor:
Aya Takahashi, Atsushi Umemura, Kota Yano, Shinya Okishio, Seita Kataoka, Keiichiro Okuda, Yuya Seko, Kanji Yamaguchi, Michihisa Moriguchi, Takeshi Okanoue, Yoshito Itoh
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Combination treatment with tyrosine kinase inhibitors (TKIs) and immunotherapies has shown efficacy in the treatment of multiple cancers, but the immunomodulatory effect of TKIs on the tumor cell phenotype remains unknown in hepatocellular carcinoma
Externí odkaz:
https://doaj.org/article/f4023ab948ff40a9a22932d21b98616e
Autor:
Yusuke Takahashi, Yuya Seko, Kanji Yamaguchi, Kento Takeuchi, Kota Yano, Seita Kataoka, Michihisa Moriguchi, Yoshito Itoh
Publikováno v:
Journal of Gastroenterology and Hepatology.
Autor:
Yu Liu, Yoshito Itoh, Kota Yano, Yuya Seko, Atsushi Umemura, Takeshi Okanoue, Michihisa Moriguchi, Seita Kataoka, Kanji Yamaguchi, Keiichiroh Okuda, Hiroshi Ishiba, Shinya Okishio, Hideki Fujii, Nozomi Tochiki, Aya Takahashi
Publikováno v:
Laboratory Investigation. 102:281-289
Fibroblast growth factor (FGF) 21 is an endocrine growth factor mainly secreted by the liver in response to a ketogenic diet and alcohol consumption. FGF21 signaling requires co-receptor β-klotho (KLB) co-acting with FGF receptors, which has pleiotr