Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kota, Nagasaka"'
Autor:
Gordana Wutz, Rene Ladurner, Brian Glenn St Hilaire, Roman R Stocsits, Kota Nagasaka, Benoit Pignard, Adrian Sanborn, Wen Tang, Csilla Várnai, Miroslav P Ivanov, Stefan Schoenfelder, Petra van der Lelij, Xingfan Huang, Gerhard Dürnberger, Elisabeth Roitinger, Karl Mechtler, Iain Finley Davidson, Peter Fraser, Erez Lieberman-Aiden, Jan-Michael Peters
Publikováno v:
eLife, Vol 9 (2020)
Eukaryotic genomes are folded into loops. It is thought that these are formed by cohesin complexes via extrusion, either until loop expansion is arrested by CTCF or until cohesin is removed from DNA by WAPL. Although WAPL limits cohesin’s chromatin
Externí odkaz:
https://doaj.org/article/50f9b518193c4de2ba8e04afd984547d
Autor:
Johann Holzmann, Antonio Z Politi, Kota Nagasaka, Merle Hantsche-Grininger, Nike Walther, Birgit Koch, Johannes Fuchs, Gerhard Dürnberger, Wen Tang, Rene Ladurner, Roman R Stocsits, Georg A Busslinger, Béla Novák, Karl Mechtler, Iain Finley Davidson, Jan Ellenberg, Jan-Michael Peters
Publikováno v:
eLife, Vol 8 (2019)
The organisation of mammalian genomes into loops and topologically associating domains (TADs) contributes to chromatin structure, gene expression and recombination. TADs and many loops are formed by cohesin and positioned by CTCF. In proliferating ce
Externí odkaz:
https://doaj.org/article/b4dd695cfba54d39a1aacd86fcfa079a
Werner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells
Autor:
Simone Lieb, Silvia Blaha-Ostermann, Elisabeth Kamper, Janine Rippka, Cornelia Schwarz, Katharina Ehrenhöfer-Wölfer, Andreas Schlattl, Andreas Wernitznig, Jesse J Lipp, Kota Nagasaka, Petra van der Lelij, Gerd Bader, Minoru Koi, Ajay Goel, Ralph A Neumüller, Jan-Michael Peters, Norbert Kraut, Mark A Pearson, Mark Petronczki, Simon Wöhrle
Publikováno v:
eLife, Vol 8 (2019)
Targeted cancer therapy is based on exploiting selective dependencies of tumor cells. By leveraging recent functional screening data of cancer cell lines we identify Werner syndrome helicase (WRN) as a novel specific vulnerability of microsatellite i
Externí odkaz:
https://doaj.org/article/bcf5373f995c49dd883a2b357adfa700
Autor:
Iain F. Davidson, Roman Barth, Maciej Zaczek, Jaco van der Torre, Wen Tang, Kota Nagasaka, Richard Janissen, Jacob Kerssemakers, Gordana Wutz, Cees Dekker, Jan-Michael Peters
Publikováno v:
Nature: international weekly journal of science, 616(7958)
In eukaryotes, genomic DNA is extruded into loops by cohesin1. By restraining this process, the DNA-binding protein CCCTC-binding factor (CTCF) generates topologically associating domains (TADs)2,3 that have important roles in gene regulation and rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba49b276480c99d3227d412f1dcf3140
http://resolver.tudelft.nl/uuid:8a5844c1-360e-41bd-8d05-b5cbb7c5a3ad
http://resolver.tudelft.nl/uuid:8a5844c1-360e-41bd-8d05-b5cbb7c5a3ad
Autor:
Stefan Schoenfelder, Brian Glenn St Hilaire, Petra van der Lelij, Jan-Michael Peters, Wen Tang, Gordana Wutz, Karl Mechtler, Iain F. Davidson, Adrian L. Sanborn, Benoit Pignard, Miroslav P Ivanov, Roman R. Stocsits, Peter Fraser, Elisabeth Roitinger, Xingfan Huang, Erez Lieberman Aiden, Kota Nagasaka, Rene Ladurner, Gerhard Dürnberger, Csilla Várnai
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Eukaryotic genomes are folded into loops. It is thought that these are formed by cohesin complexes via extrusion, either until loop expansion is arrested by CTCF or until cohesin is removed from DNA by WAPL. Although WAPL limits cohesin’s chromatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c4e248dc34f280439bceca79883c99
Autor:
Adrian L. Sanborn, Elisabeth Roitinger, Gordana Wutz, Miroslav P Ivanov, Rene Ladurner, Petra van der Lelij, Xingfan Huang, Kota Nagasaka, Stefan Schoenfelder, Gerhard Dürnberger, Csilla Várnai, Iain F. Davidson, Roman R. Stocsits, Peter Fraser, Brian Glenn St Hilaire, Benoit Pignard, Karl Mechtler, Erez Lieberman-Aiden, Jan-Michael Peters, Wen Tang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6c98df71591813ef0c13098de15676d
https://doi.org/10.7554/elife.52091.sa2
https://doi.org/10.7554/elife.52091.sa2
Autor:
Jan Ellenberg, Csilla Várnai, David A. Cisneros, Jan-Michael Peters, Johannes Zuber, Moritz Kueblbeck, Birgit Koch, Wen Tang, Stefan Schoenfelder, Matthias Muhar, M. Julius Hossain, Gregor Jessberger, Nike Walther, Gordana Wutz, Roman R. Stocsits, Peter Fraser, Kota Nagasaka
Publikováno v:
The EMBO Journal. 36:3573-3599
Mammalian genomes are spatially organized into compartments, topologically associating domains (TADs), and loops to facilitate gene regulation and other chromosomal functions. How compartments, TAD ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5d39a9929dd5526d318931f38173d45
https://doi.org/10.15252/embj.201798004
https://doi.org/10.15252/embj.201798004
Autor:
Minji Jo, Motoko Takahashi, Hiroshi Masumoto, Katsushi Shibata, Kazuhiko S.K. Uchida, Toru Hirota, Kota Nagasaka, Tatsuo Fukagawa, Kozo Tanaka, Norihisa Shindo
Publikováno v:
Curr Biol
The spindle-assembly checkpoint facilitates mitotic fidelity by delaying anaphase onset in response to microtubule vacancy at kinetochores. Following microtubule attachment, kinetochores receive microtubule-derived force, which causes kinetochores to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e82f5a533efaab6d6e8120b1881bd9
https://pubmed.ncbi.nlm.nih.gov/33905696
https://pubmed.ncbi.nlm.nih.gov/33905696
Autor:
Gordana, Wutz, Rene, Ladurner, Brian Glenn, St Hilaire, Roman R, Stocsits, Kota, Nagasaka, Benoit, Pignard, Adrian, Sanborn, Wen, Tang, Csilla, Várnai, Miroslav P, Ivanov, Stefan, Schoenfelder, Petra, van der Lelij, Xingfan, Huang, Gerhard, Dürnberger, Elisabeth, Roitinger, Karl, Mechtler, Iain Finley, Davidson, Peter, Fraser, Erez, Lieberman-Aiden, Jan-Michael, Peters
Publikováno v:
eLife
Eukaryotic genomes are folded into loops. It is thought that these are formed by cohesin complexes via extrusion, either until loop expansion is arrested by CTCF or until cohesin is removed from DNA by WAPL. Although WAPL limits cohesin’s chromatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4dc5688f89331d4bc7276cb4c3262925
https://pubmed.ncbi.nlm.nih.gov/32065581
https://pubmed.ncbi.nlm.nih.gov/32065581
Autor:
Bela Novak, Antonio Z. Politi, Iain F. Davidson, Jan-Michael Peters, Wen Tang, Johann Holzmann, Gerhard Dürnberger, Georg A. Busslinger, Birgit Koch, Jan Ellenberg, Kota Nagasaka, Rene Ladurner, Nike Walther, Merle Hantsche-Grininger, Johannes Fuchs, Karl Mechtler, Roman R. Stocsits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b25d294a3a2b79852a7eb980c6a02964
https://doi.org/10.7554/elife.46269.033
https://doi.org/10.7554/elife.46269.033