Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kosuke Winston"'
Autor:
Paul N. Valdmanis, Mark A. Kay, Cynthia V. Bourassa, Kathryn Gudsnuk, Meredith M. Course, Nicolas Dupré, Guy A. Rouleau, Suman Jayadev, Dan Spiegelman, Chang En Yu, Evan E. Eichler, Samuel N. Smukowski, Arvis Sulovari, Debby W. Tsuang, Jay P. Ross, Nitin Desai, Aaron D. Gitler, Julien Couthouis, Kosuke Winston, Patrick A. Dion
Publikováno v:
Am J Hum Genet
Tandem repeats are proposed to contribute to human-specific traits, and more than 40 tandem repeat expansions are known to cause neurological disease. Here, we characterize a human-specific 69 bp variable number tandem repeat (VNTR) in the last intro
Organoid cystogenesis reveals a critical role of microenvironment in human polycystic kidney disease
Autor:
York Pei, Laura S. Finn, Jonathan Himmelfarb, Ramila E. Gulieva, Nelly M. Cruz, Benjamin S. Freedman, Angela J. Churchill, Yong Kyun Kim, Hongxia Fu, Linh M. Tran, Xuewen Song, Marco A. Diaz, Kosuke Winston, Stefan Czerniecki
Publikováno v:
Nature materials
Tissue mimics are of great interest in understanding diseases. Here, organoids were developed that resemble polycystic kidney disease cysts and it was demonstrated how material environment and adhesion can affect cystogenesis and disease progression.
Publikováno v:
Optics in the Life Sciences Congress.