Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Kosuke Tanegashima"'
Autor:
Kosuke Tanegashima, Rena Takahashi, Hideko Nuriya, Rina Iwase, Naoto Naruse, Kohei Tsuji, Akira Shigenaga, Akira Otaka, Takahiko Hara
Publikováno v:
EBioMedicine, Vol 24, Iss C, Pp 247-256 (2017)
CXCL14 is a primordial chemokine that plays multiple roles in tumor suppression, autoimmune arthritis, and obesity-associated insulin resistance. However, the underlying molecular mechanisms are unclear. Here, we show that CXCL14 transports various t
Externí odkaz:
https://doaj.org/article/f048954521c2406293e2893fe84fb88f
Autor:
Kosuke Tanegashima, Shiki Okamoto, Yuki Nakayama, Choji Taya, Hiroshi Shitara, Rie Ishii, Hiromichi Yonekawa, Yasuhiko Minokoshi, Takahiko Hara
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10321 (2010)
BACKGROUND: CXCL14 is a chemoattractant for macrophages and immature dendritic cells. We recently reported that CXCL14-deficient (CXCL14(-/-)) female mice in the mixed background are protected from obesity-induced hyperglycemia and insulin resistance
Externí odkaz:
https://doaj.org/article/05a836ce881e4b3db5ecb24c99208f4a
Autor:
Kojiro Tsujihana, Kosuke Tanegashima, Yasuko Santo, Hiroyuki Yamada, Sota Akazawa, Ryuta Nakao, Keiko Tominaga, Risa Saito, Yasumasa Nishito, Ryu-Ichiro Hata, Tomonori Nakamura, Iori Murai, Yuka Kono, Maho Sugawa, Miki Tanioka, Gyohei Egawa, Masao Doi, Tadashi Isa, Kenji Kabashima, Takahiko Hara, Hitoshi Okamura
Publikováno v:
Proceedings of the National Academy of Sciences (PNAS). 119(25)
The epidermis is the outermost layer of the skin and the body’s primary barrier to external pathogens; however, the early epidermal immune response remains to be mechanistically understood. We show that the chemokine CXCL14, produced by epidermal k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c3800fdfdc37c839492a8a5a79c746
http://hdl.handle.net/2433/277870
http://hdl.handle.net/2433/277870
Autor:
Rena Takahashi, Naoto Naruse, Rina Iwase, Kohei Tsuji, Akira Shigenaga, Hideko Nuriya, Takahiko Hara, Akira Otaka, Kosuke Tanegashima
Publikováno v:
EBioMedicine
EBioMedicine, Vol 24, Iss C, Pp 247-256 (2017)
EBioMedicine, Vol 24, Iss C, Pp 247-256 (2017)
CXCL14 is a primordial chemokine that plays multiple roles in tumor suppression, autoimmune arthritis, and obesity-associated insulin resistance. However, the underlying molecular mechanisms are unclear. Here, we show that CXCL14 transports various t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21977e4a7d6474bf4ed2f8e5479b1c88
https://doi.org/10.1016/j.ebiom.2017.09.012
https://doi.org/10.1016/j.ebiom.2017.09.012
Autor:
Masabumi Funakoshi, Takahiko Hara, Yasumasa Nishito, Yukiko Sato-Miyata, Toshiro Aigaki, Kosuke Tanegashima
Publikováno v:
Genes to Cells. 22:71-83
We carried out liquid chromatography-tandem mass spectrometry analysis of metabolites in mice. Those metabolome data showed that hepatic glucose content is reduced, but that brain glucose content is unaffected, during fasting, consistent with the pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ed3e7f5a0b0ec713ee1597dead6009
https://doi.org/10.1111/gtc.12456
https://doi.org/10.1111/gtc.12456
Publikováno v:
The International journal of developmental biology. 63(1-2)
Latrophilin2 (Lphn2) is an adhesion-class of G protein-coupled receptor with an unknown function in development. Here, we show that Xenopus laevis lphn2 (Xlphn2) is involved in the migration and differentiation of neural crest (NC) cells and placode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86712b1f30cdd5d3545b3fb7063181a6
https://pubmed.ncbi.nlm.nih.gov/30919913
https://pubmed.ncbi.nlm.nih.gov/30919913
Autor:
Kohei Sato, Kohei Tsuji, Akira Otaka, Kosuke Tanegashima, Tsubasa Inokuma, Akira Shigenaga, Ken Sakamoto, Takahiko Hara
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:5909-5914
CXCL14 is a CXC-type chemokine that exhibits chemotactic activity for immature dendritic cells, activated macrophages, and activated natural killer cells. However, its specific receptor and signaling pathway remain obscure. Recently, it was reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c378b957f1b16b10362e8647e01d06
https://doi.org/10.1016/j.bmc.2015.06.064
https://doi.org/10.1016/j.bmc.2015.06.064
Autor:
Yusaku Kodaka, Takahiko Hara, Kosuke Tanegashima, Kenji Kitajima, Kiyoko Tanaka, Ryoichi Matsuda
Publikováno v:
Experimental Cell Research. 331:309-319
LIM homeobox transcription factor Lhx2 is known to be an important regulator of neuronal development, homeostasis of hair follicle stem cells, and self-renewal of hematopoietic stem cells; however, its function in skeletal muscle development is poorl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3079c6542090917b5ce311d0e8f50e32
https://doi.org/10.1016/j.yexcr.2014.11.009
https://doi.org/10.1016/j.yexcr.2014.11.009
Autor:
Kohei Tsuji, Yuki Nakayama, Takahiko Hara, Akira Shigenaga, Kosuke Tanegashima, Kenji Suzuki, Akira Otaka
Publikováno v:
FEBS Letters. 587:1731-1735
Activation of the CXCL12–CXCR4 pathway is crucial for the migration of hematopoietic stem cells, various immune cells, and malignant tumor cells. Here, we show that another CXC chemokine, CXCL14, specifically binds to CXCR4 with high affinity and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::307a222827b9d50f14532792ae45bee8
https://doi.org/10.1016/j.febslet.2013.04.046
https://doi.org/10.1016/j.febslet.2013.04.046
Autor:
Takahiko Hara, Kosuke Tanegashima
Publikováno v:
Journal of Biochemistry. 151:469-476
CXCL14 is a member of the CXC chemokine family. CXCL14 possesses chemoattractive activity for activated macrophages, immature dendritic cells and natural killer cells. CXCL14-deficient mice do not exhibit clear immune system abnormalities, suggesting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c0df8d33d1cb4265df8ade48811174
https://doi.org/10.1093/jb/mvs030
https://doi.org/10.1093/jb/mvs030