Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Kosuke Mizutani"'
Autor:
Kosuke Mizutani, Kyojiro Kawakami, Yasunori Fujita, Taku Kato, Manabu Takai, Daiki Kato, Koji Iinuma, Takuya Koie, Masafumi Ito
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Perforin secreted from cytotoxic lymphocytes plays a critical role in cancer immunosurveillance. The aim of this study was to investigate the therapeutic potential of liposomes containing perforin expression vector driven by the promotor of
Externí odkaz:
https://doaj.org/article/5098d9939ad0449491be2f71e16aada4
Autor:
Kyojiro Kawakami, Yasunori Fujita, Taku Kato, Kengo Horie, Takuya Koie, Keitaro Umezawa, Hiroki Tsumoto, Yuri Miura, Yasuo Katagiri, Tatsuhiko Miyazaki, Ikuroh Ohsawa, Kosuke Mizutani, Masafumi Ito
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract We aimed to develop a sandwich ELISA to detect prostate-specific membrane antigen (PSMA) on small extracellular vesicles (EVs) using T-cell immunoglobulin domain and mucin domain-containing protein 4 (Tim4) as a capture molecule for EVs and
Externí odkaz:
https://doaj.org/article/648dd70978a8435eb6429fb1ecaa1541
Autor:
Yanhui Zhu, Kosuke Mizutani, Kenji Minami, Hokuto Shirakawa, Yohei Kawauchi, Huamei Shao, Makoto Tomiyasu, Yuka Iwahara, Tsutomu Tamura, Masahiro Ogawa, Kai Tatsuyama, Kazushi Miyashita
Publikováno v:
Journal of Marine Science and Engineering, Vol 10, Iss 7, p 966 (2022)
The sandeel species (Ammodytes spp.) occupy a critical ecological position in connecting lower trophic levels to higher ones. However, they are strongly affected by the marine environment and their catch rates are trending downward. In this study, th
Externí odkaz:
https://doaj.org/article/83e6046e1b804e27b5f49971cb217f06
Publikováno v:
Heliyon, Vol 6, Iss 7, Pp e04138- (2020)
Background: Docetaxel is first-line chemotherapy for castration-resistant prostate cancer (CRPC), but most patients acquire docetaxel resistance. CD44 has been shown to be involved in drug resistance of cancers including prostate cancer. We hypothesi
Externí odkaz:
https://doaj.org/article/5b490c5b268d46d382383d6b64bd0252
Autor:
Kyojiro Kawakami, Yasunori Fujita, Yoko Matsuda, Tomio Arai, Kengo Horie, Koji Kameyama, Taku Kato, Koichi Masunaga, Yutaka Kasuya, Masashi Tanaka, Kosuke Mizutani, Takashi Deguchi, Masafumi Ito
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-12 (2017)
Abstract Background Exosomes or extracellular vesicles have the potential as a diagnostic marker for various diseases including cancer. In order to identify novel exosomal markers for prostate cancer (PC), we performed proteomic analysis of exosomes
Externí odkaz:
https://doaj.org/article/c07ab5b352354beab0ca82f100c59a10
Autor:
Kimiaki Takagi, Manabu Takai, Koji Kameyama, Kengo Horie, Mina Kikuchi, Taku Kato, Kosuke Mizutani, Kensaku Seike, Tomohiro Tsuchiya, Mitsuru Yasuda, Shigeaki Yokoi, Natsuko Suzui, Masahiro Nakano, Takashi Deguchi
Publikováno v:
Urology Case Reports, Vol 3, Iss 5, Pp 138-140 (2015)
A 26-year-old woman with gross hematuria was seen in a previous hospital. Magnetic resonance imaging (MRI) showed a tumor at the dome of the urinary bladder with invasion outside of the bladder wall. The patient underwent transurethral resection of t
Externí odkaz:
https://doaj.org/article/3253fd01526d4a7781233ce068996bb1
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 1, Pp 23-30 (2011)
Macrophages within the tumor microenvironment promote angiogenesis, extracellular matrix breakdown, and tumor cell migration, invasion, and metastasis. Activation of the urokinase plasminogen activator (uPA) and its receptor (uPAR) axis promotes pros
Externí odkaz:
https://doaj.org/article/59f7dfd6c00944afb47b692a16651bd7
Autor:
Kosuke Mizutani, Sudha Sud, Natalie A. McGregor, Gari Martinovski, Brandon T. Rice, Matthew J. Craig, Zachary S. Varsos, Hernan Roca, Kenneth J. Pienta
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 11, Pp 1235-1242 (2009)
CC chemokine ligand 2 (CCL2, also known as monocyte chemoattractant protein-1) has been demonstrated to recruit monocytes to tumor sites. Monocytes are capable of being differentiated into tumor-associated macrophages (TAMs) and osteoclasts (OCs). TA
Externí odkaz:
https://doaj.org/article/d4817fd166374312a7c1ab62171e41b6
Autor:
Kosuke Mizutani, Yuki Yoshida, Eita Nakanishi, Yugo Miyata, Shoko Tokumoto, Hiroto Fuse, Oleg Gusev, Shingo Kikuta, Takahiro Kikawada
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 4/2/2024, Vol. 121 Issue 14, p1-12, 23p
Autor:
KOSUKE MIZUTANI, SEIJI SUGIYAMA, KOJI KAMEYAMA, SHINGO KAMEI, SHIGEAKI YOKOI, AKEMI MORIKAWA, MAKOTO TAKEUCHI, KENSAKU SEIKE, TORU YAMADA, HIDETOSHI EHARA, SEIYA SAWADA, KOUSEKI HIRADE, HIROHITO FURUTA, KENGO MATSUNAGA, TETSUYA YAMADA, IPPEI SAKAMOTO, YASUTAKA KATO, HIROSHI NISHIHARA, SATOSHI ISHIHARA, TAKASHI DEGUCHI
Publikováno v:
Cancer Genomics & Proteomics (1109-6535); Mar/Apr2024, Vol. 21 Issue 2, p203-212, 10p