Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Kosuke Maki"'
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134238 (2015)
In this study, the equivalence of the kinetic mechanisms of the formation of urea-induced kinetic folding intermediates and non-native equilibrium states was investigated in apomyoglobin. Despite having similar structural properties, equilibrium and
Externí odkaz:
https://doaj.org/article/63469a2689364232af69a99af8994b66
Publikováno v:
Biochemistry.
Autor:
Hisashi Okumura, Teikichi Ikura, Takuya Mizukami, Kosuke Maki, Kunio Ihara, Saho Segawa, Satoru G. Itoh, Heinrich Roder, Shunta Furuzawa
Publikováno v:
Proc Natl Acad Sci U S A
Protein conformational changes associated with ligand binding, especially those involving intrinsically disordered proteins, are mediated by tightly coupled intra- and intermolecular events. Such reactions are often discussed in terms of two limiting
Publikováno v:
Biochemistry. 57:6013-6026
The anion pumping cycle of halorhodopsin from Natronomonas pharaonis (pHR) is initiated when the all-trans/15-anti isomer of retinal is photoisomerized into the 13-cis/15-anti configuration. A recent crystallographic study suggested that a reaction s
Publikováno v:
Case Reports in Hematology, Vol 2024 (2024)
Human immunodeficiency virus (HIV)-associated lymphoma poses a high mortality risk despite antiretroviral therapy (ART). Although intermediate- or high-grade B-cell lymphomas are common, anaplastic large-cell lymphomas (ALCLs) are rare and seldom aff
Externí odkaz:
https://doaj.org/article/35571ce2a74a4129a68d6181624bd87c
Autor:
Tsutomu Kouyama, Siu Kit Chan, Haruki Kawaguchi, Midori Murakami, Kunio Ihara, Hiroki Kubo, Kosuke Maki
Publikováno v:
Biochemistry. 55:4092-4104
Like other microbial rhodopsins, the light driven chloride pump halorhodopsin from Natronomonas pharaonis (pHR) contains a mixture of all-trans/15-anti and 13-cis/15-syn isomers in the dark adapted state. A recent crystallographic study of the reacti
Autor:
Takuya Mizukami, Shunta Furuzawa, Itoh, Satoru G., Saho Segawa, Teikichi Ikura, Kunio Ihara, Hisashi Okumura, Heinrich Roder, Kosuke Maki
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 8/18/2020, Vol. 117 Issue 33, p19953-19962, 10p
Publikováno v:
Protein Science. 22:1336-1348
The development of tertiary structure during folding of staphylococcal nuclease (SNase) was studied by time-resolved fluorescence resonance energy transfer measured using continuous- and stopped-flow techniques. Variants of this two-domain protein co
Publikováno v:
Journal of Molecular Biology. 425:257-272
The kinetic folding of β2-microglobulin from the acid-denatured state was investigated by interrupted-unfolding and interrupted-refolding experiments using stopped-flow double-jump techniques. In the interrupted unfolding, we first unfolded the prot
Publikováno v:
The journal of physical chemistry. B. 120(34)
Despite the major role of pH in protein folding and stability, a quantitative understanding of the pH-induced protein folding mechanism remains elusive. Two conventional models, the Monod-Wyman-Changeux and Linderstrøm-Lang smeared charge models, re