Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kosuke, Fujio"'
Autor:
Haruki Okamoto, Kosuke Fujio, Sou Nakamura, Yasuo Harada, Hideki Hayashi, Natsumi Higashi, Atsushi Ninomiya, Ryota Tanaka, Naoshi Sugimoto, Naoya Takayama, Atsushi Kaneda, Akira Sawaguchi, Yoshikazu Kato, Koji Eto
Publikováno v:
Communications Engineering, Vol 3, Iss 1, Pp 1-12 (2024)
Abstract To complement donor-dependent platelets supplies, we previously developed an ex vivo manufacturing system using induced pluripotent stem cell (iPSC)-derived expandable immortalized megakaryocyte progenitor cell lines (imMKCLs), and a turbule
Externí odkaz:
https://doaj.org/article/63fcf19140a243b786caa7c95234af29
Autor:
Si Jing Chen, Kazuya Hashimoto, Kosuke Fujio, Karin Hayashi, Sudip Kumar Paul, Akinori Yuzuriha, Wei-Yin Qiu, Emiri Nakamura, Maria Alejandra Kanashiro, Mio Kabata, Sou Nakamura, Naoshi Sugimoto, Atsushi Kaneda, Takuya Yamamoto, Hirohide Saito, Naoya Takayama, Koji Eto
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract We recently achieved the first-in-human transfusion of induced pluripotent stem cell-derived platelets (iPSC-PLTs) as an alternative to standard transfusions, which are dependent on donors and therefore variable in supply. However, heterogen
Externí odkaz:
https://doaj.org/article/e076073440bb424492d68b3e50922502
Autor:
Daisuke Suzuki, Charlotte Flahou, Norihide Yoshikawa, Ieva Stirblyte, Yoshikazu Hayashi, Akira Sawaguchi, Marina Akasaka, Sou Nakamura, Natsumi Higashi, Huaigeng Xu, Takuya Matsumoto, Kosuke Fujio, Markus G. Manz, Akitsu Hotta, Hitoshi Takizawa, Koji Eto, Naoshi Sugimoto
Publikováno v:
Stem Cell Reports, Vol 14, Iss 1, Pp 49-59 (2020)
Summary: The ex vivo production of platelets depleted of human leukocyte antigen class I (HLA-I) could serve as a universal measure to overcome platelet transfusion refractoriness caused by HLA-I incompatibility. Here, we developed human induced plur
Externí odkaz:
https://doaj.org/article/9f437e1b02f6488582832358c907a1bf
Publikováno v:
Open Forum Infectious Diseases. 9
Background Amenamevir is a helicase-primase inhibitor with novel mechanisms of antiherpetic action. A patient-initiated single-dose regimen showed clinical efficacy for genital herpes in a phase 2 study. Methods In this phase 3 study, adult immunocom
Publikováno v:
The Journal of dermatologyREFERENCES.
Amenamevir (ASP2151), a novel, non-nucleoside analog, antiviral drug, inhibits the enzyme activities of helicase and primase, which are essential for replication of herpes viral genomic DNA. In this phase 3, randomized, double-blind, placebo-controll
Autor:
Natsumi Higashi, Yoshikazu Hayashi, Akitsu Hotta, Kosuke Fujio, Hitoshi Takizawa, Koji Eto, Markus G. Manz, Marina Akasaka, Charlotte Flahou, Huaigeng Xu, Takuya Matsumoto, Sou Nakamura, Daisuke Suzuki, Norihide Yoshikawa, Naoshi Sugimoto, Ieva Stirblyte, Akira Sawaguchi
Publikováno v:
Stem Cell Reports, Vol 14, Iss 1, Pp 49-59 (2020)
Stem Cell Reports
Stem Cell Reports
Summary The ex vivo production of platelets depleted of human leukocyte antigen class I (HLA-I) could serve as a universal measure to overcome platelet transfusion refractoriness caused by HLA-I incompatibility. Here, we developed human induced pluri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d31e2a5eb0ae00a52465f0d6628715
https://doi.org/10.5167/uzh-180152
https://doi.org/10.5167/uzh-180152
Autor:
Tomohiro Shigemori, Mio Iwasaki, Keitaro Ito, Sou Nakamura, Masato Nakagawa, Kosuke Fujio, Akira Sawaguchi, Masayuki Nogawa, Ito Yukitaka, Koji Eto, Ken ichi Harimoto, Kato Yoshikazu, Kazuya Hashimoto, Makoto Handa, Takuya Matsumoto, Fumihito Arai, Mikiko Ohno, Natsumi Higashi, Naoshi Sugimoto, Takuya Yamamoto, Okamoto Haruki, Shunsuke Kihara, Hiroki Kumon, Hidenori Hirose, Shinya Sakuma, Naohide Watanabe, Satoshi Nishimura, Eiichiro Nishi
Publikováno v:
Cell. 174:636-648.e18
The ex vivo generation of platelets from human-induced pluripotent cells (hiPSCs) is expected to compensate donor-dependent transfusion systems. However, manufacturing the clinically required number of platelets remains unachieved due to the low plat
Publikováno v:
Japanese Journal of Food Microbiology. 23:242-246
Autor:
Junichi Kawano, Kosuke Fujio, Hiroshi Kitagawa, Eri Sato, Akira Shimizu, Tetsurou Inamoto, Ryo Yasuda, Chisa Nakano, Kosuke Matsumura, Satoru Kitai
Publikováno v:
Journal of Veterinary Medical Science. 67:269-274
A total of 444 samples of raw chicken meat (thighs, breasts, wings, livers, gizzards, hearts and ovaries) that retailed at 145 different supermarkets in 47 prefectures in Japan were examined for contamination with Staphylococcus aureus in association