Zobrazeno 1 - 10 of 58 pro vyhledávání: '"Kosuke, Doki"'
1
Akademický článek
Increased serum amiodarone concentration in hypertriglyceridemic patients: Effects of drug distribution to serum lipoproteins
Autor: Naoaki Hashimoto, Kosuke Doki, Satoru Kawano, Kazutaka Aonuma, Masaki Ieda, Masato Homma
Publikováno v: Clinical and Translational Science, Vol 15, Iss 3, Pp 771-781 (2022)
Abstract Amiodarone and its main metabolite, desethylamiodarone (DEA), are highly distributed to serum lipoproteins such as very‐low‐density lipoprotein (VLDL) and low‐density lipoprotein (LDL), which are the carriers of triglyceride and choles
Externí odkaz: https://doaj.org/article/71a5ebee272046b5b5ba2dba3473efc9
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2
Akademický článek
Rationale and design of a multicenter, double-blinded, randomized, placebo-controlled trial to investigate the effects of naldemedine on opioid-induced constipation for patients with cancer pain: A study protocol
Autor: Takahiro Higashibata, Jun Hamano, Takaomi Kessoku, Shinya Kajiura, Mami Hirakawa, Yoshiki Horie, Masaki Shimizu, Shunsuke Oyamada, Keisuke Ariyoshi, Kota Kihara, Yohei Yamanaka, Kumi Konishi, Kosuke Doki, Yasuyuki Takashima, Manabu Horiuchi, Masato Homma, Takeshi Yamada, Yoshiyuki Yamamoto, Toshikazu Moriwaki, Tatsuya Morita, Atsushi Nakajima, Hiroka Nagaoka
Publikováno v: Contemporary Clinical Trials Communications, Vol 29, Iss , Pp 100967- (2022)
Background: It is unclear which laxatives are appropriate to prevent opioid-induced constipation (OIC). This study will evaluate whether prophylactic use of naldemedine prevents OIC in patients with cancer who start opioid administration. Methods: Th
Externí odkaz: https://doaj.org/article/2c8bc9ec4bb74ae79dd65110a614344a
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3
Akademický článek
A Follow-Up Report of an Infant Born to a Mother Receiving Tamoxifen
Autor: Yuki Okada, Daisuke Hitaka, Takahiro Kido, Yu Kanai, Kumi Konishi, Kosuke Doki, Nobuko Katayama, Masato Homma, Yayoi Miyazono, Hidetoshi Takada
Publikováno v: Case Reports in Pediatrics, Vol 2020 (2020)
Tamoxifen, an estrogen receptor antagonist, is contraindicated in pregnant women due to its teratogenic activity. In the present study, we report the case of an infant whose mother received tamoxifen for breast cancer while unaware of the pregnancy.
Externí odkaz: https://doaj.org/article/b05de5d3576c4bab834239e679eaa2a1
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4
Increased serum amiodarone concentration in hypertriglyceridemic patients: Effects of drug distribution to serum lipoproteins
Autor: Satoru Kawano, Masaki Ieda, Kazutaka Aonuma, Masato Homma, Naoaki Hashimoto, Kosuke Doki
Publikováno v: Clinical and Translational Science. 15:771-781
Amiodarone and its main metabolite, desethylamiodarone, are highly distributed to serum lipoproteins such as very-low-density lipoprotein (VLDL) and low-density lipoprotein (LDL), which are the carriers of triglyceride and cholesterol. This study aim
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4820ff75cde18d0abcfdd6a22e58cf9d
https://doi.org/10.1111/cts.13199
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5
Distribution of therapeutic monoclonal antibodies into ascites in advanced gastric cancer patients with peritoneal metastasis: case reports and literature review
Autor: Takuya Kaneko, Kosuke Doki, Takeshi Yamada, Yoshiyuki Yamamoto, Toshikazu Moriwaki, Yoshiharu Suzuki, Masato Homma
Publikováno v: Cancer chemotherapy and pharmacology. 90(5)
Therapeutic monoclonal antibodies, including ramucirumab and nivolumab, are used to treat advanced gastric cancer (AGC). Malignant ascites is often accompanied by peritoneal metastasis in AGC patients. However, the distribution of therapeutic monoclo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193ab6425f0d1575057f1e4928eaf470
https://pubmed.ncbi.nlm.nih.gov/36180639
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8
Effect of CYP2D6 genetic polymorphism on peak propafenone concentration: no significant effect of CYP2D6*10
Autor: Yukinao Kohda, Masato Homma, Masaki Ieda, Yuki Shirayama, Yukio Sekiguchi, Kazutaka Aonuma, Kosuke Doki
Publikováno v: Pharmacogenomics. 21:1279-1288
Aim: The study aims to investigate the clinical implication of nonfunctional poor metabolizer (PM) alleles and intermediate metabolizer (IM) alleles of CYP2D6, including the CYP2D6*10 allele which shows substrate-dependent decrease in enzymatic activ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5d3aff1e4d22748a6701c0b431137a11
https://doi.org/10.2217/pgs-2020-0105
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10
High-Performance Liquid Chromatography for Therapeutic Drug Monitoring of Serum Lenvatinib
Autor: Yusuke Watanabe, Kosuke Doki, Hisato Hara, Masato Homma, Ikuo Sekine
Publikováno v: Therapeutic Drug Monitoring. 42:554-558
Therapeutic drug monitoring (TDM) and dose adjustment of lenvatinib may be beneficial in the treatment of radioiodine-refractory thyroid cancer, by maximizing antitumor effects and minimizing adverse drug reactions. The aim of this study was, therefo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8b2ca6d670fb7050f41f0a2fcb245a
https://doi.org/10.1097/ftd.0000000000000770
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