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pro vyhledávání: '"Kostrzewa, Richard M"'
Autor:
Kostrzewa, John P.1 (AUTHOR), Kostrzewa, Richard M.2,3 (AUTHOR) kostrzew@etsu.edu
Publikováno v:
Neurotoxicity Research. Mar2020, Vol. 37 Issue 3, p543-552. 10p.
Akademický článek
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Autor:
Kostrzewa, Richard M.
Publikováno v:
ETSU Authors Bookshelf.
© Springer Science+Business Media New York 2014. All rights reserved. The Handbook of Neurotoxicity is a reference source for identifying, characterizing, instructing on use, and describing outcomes of neurotoxin treatments - to understand mechanism
Externí odkaz:
https://dc.etsu.edu/etsu_books/212
Autor:
Kostrzewa, Richard M.
Publikováno v:
ETSU Faculty Works.
The discovery that melanized neurons of the pars compacta of substantia nigra (pcSN) degenerate in the midbrain of human Parkinsonians is nearly a century old, but only in this decade have we gained insights into mechanisms underlying this neuronal l
Externí odkaz:
https://dc.etsu.edu/etsu-works-2/290
Autor:
Kostrzewa, Richard M.
Publikováno v:
ETSU Faculty Works.
For centuries, starting with the advent of the microscope, cytotoxins have been known to non-selectively destroy nerves and other tissue cells. However, neurotoxins restricted in effect to one kind of neuron are an invention of the 20th century. One
Externí odkaz:
https://dc.etsu.edu/etsu-works-2/291
Autor:
Kostrzewa, Richard M.
Publikováno v:
ETSU Faculty Works.
Externí odkaz:
https://dc.etsu.edu/etsu-works-2/32
Autor:
Kostrzewa, Richard M.
Publikováno v:
ETSU Faculty Works.
The neurotoxin 6-hydroxydopamine (6-OHDA), following pretreatment with the norepinephrine transport inhibitor desipramine, selectively destroys dopaminergic neurons. When given to rats, neonatal 6-OHDA (n6-OHDA) crosses the blood-brain barrier to des
Externí odkaz:
https://dc.etsu.edu/etsu-works-2/44
Publikováno v:
ETSU Faculty Works.
In multicellular organisms, all the cells are genetically identical but turn genes on or off at the right time to promote differentiation into specific cell types. The regulation of higher-order chromatin structure is essential for genome-wide reprog
Autor:
Bałasz, Michał, Szkilnik, Ryszard, Brus, Ryszard, Malinowska-Borowska, Jolanta, Kasperczyk, Sławomir, Nowak, Damian, Kostrzewa, Richard M., Nowak, Przemysław
Publikováno v:
ETSU Faculty Works.
The present study was designed to investigate the role of pre- and postnatal manganese (Mn) exposure on hydroxyl radical (HO•) formation in the brains of dopamine (DA) partially denervated rats (Parkinsonian rats). Wistar rats were given tap water