Deep Sequencing and Functional Analyses Identify a Role of Fusobacterium Species in Colorectal Tumorigenesis

Autor: Kostic, Aleksandar David

The tumor microenvironment is a complex community consisting of neoplastic cells, surrounding stromal cells, a broad array of immune cells, and a microbiota. By sheer numbers, the microbiota has its greatest manifestation in colorectal cancer (CRC) b

Externí odkaz: http://dissertations.umi.com/gsas.harvard:10843
http://nrs.harvard.edu/urn-3:HUL.InstRepos:11129202

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Reproducible and opposing gut microbiome signatures distinguish autoimmune diseases and cancers: a systematic review and meta-analysis

Autor: Islam, Md Zohorul, Tran, Melissa, Xu, Tao, Tierney, Braden T., Patel, Chirag, Kostic, Aleksandar David

Publikováno v: Islam, M Z, Tran, M, Xu, T, Tierney, B T, Patel, C & Kostic, A D 2022, ' Reproducible and opposing gut microbiome signatures distinguish autoimmune diseases and cancers : a systematic review and meta-analysis ', Microbiome, vol. 10, 218 . https://doi.org/10.1186/s40168-022-01373-1

Background The gut microbiome promotes specific immune responses, and in turn, the immune system has a hand in shaping the microbiome. Cancer and autoimmune diseases are two major disease families that result from the contrasting manifestations of im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bde03ba9a3f1f9634ece86d150fdb045
https://pubmed.ncbi.nlm.nih.gov/36482486

Editorial: Gut microbiome, metabolites, and immune response in lupus, rheumatoid arthritis, and Sjögren syndrome.

Autor: Lidan Zhao, Kostic, Aleksandar David, Xuan Zhang

Publikováno v: Frontiers in Immunology; 1/16/2023, Vol. 13, p1-2, 2p