Výsledky vyhledávání - "Kostewicz ES"

Akademický článek

A combined in vitro in-silico approach to predict the oral bioavailability of borderline BCS Class II/IV weak base albendazole and its main metabolite albendazole sulfoxide.

Autor: Pettarin M; Institute of Pharmaceutical Technology, Goethe University, Frankfurt am Main, Germany., Bolger MB; Simulations Plus, Inc., Lancaster, CA 93534, United States., Chronowska M; Institute of Pharmaceutical Technology, Goethe University, Frankfurt am Main, Germany., Kostewicz ES; Institute of Pharmaceutical Technology, Goethe University, Frankfurt am Main, Germany. Electronic address: Kostewicz@em.uni-frankfurt.de.

Publikováno v: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2020 Dec 01; Vol. 155, pp. 105552. Date of Electronic Publication: 2020 Sep 13.

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Akademický článek

Effects of medicines used to treat gastrointestinal diseases on the pharmacokinetics of coadministered drugs: a PEARRL Review.

Autor: Litou C; Institute of Pharmaceutical Technology, Goethe University, Frankfurt am Main, Germany., Effinger A; Department of Pharmacy and Pharmacology, Faculty of Science, University of Bath, Bath, UK., Kostewicz ES; Institute of Pharmaceutical Technology, Goethe University, Frankfurt am Main, Germany., Box KJ; Pion Inc. (UK) Ltd., Forest Row, East Sussex, UK., Fotaki N; Department of Pharmacy and Pharmacology, Faculty of Science, University of Bath, Bath, UK., Dressman JB; Institute of Pharmaceutical Technology, Goethe University, Frankfurt am Main, Germany.

Publikováno v: The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2019 Apr; Vol. 71 (4), pp. 643-673. Date of Electronic Publication: 2018 Jul 30.

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Akademický článek

The pig as a preclinical model for predicting oral bioavailability and in vivo performance of pharmaceutical oral dosage forms: a PEARRL review.

Autor: Henze LJ; School of Pharmacy, University College Cork, Cork, Ireland., Koehl NJ; School of Pharmacy, University College Cork, Cork, Ireland., O'Shea JP; School of Pharmacy, University College Cork, Cork, Ireland., Kostewicz ES; Institute of Pharmaceutical Technology, Goethe University, Frankfurt am Main, Germany., Holm R; Drug Product Development, Janssen Research and Development, Johnson & Johnson, Beerse, Belgium., Griffin BT; School of Pharmacy, University College Cork, Cork, Ireland.

Publikováno v: The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2019 Apr; Vol. 71 (4), pp. 581-602. Date of Electronic Publication: 2018 Apr 10.

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Akademický článek

In vitro methods to assess drug precipitation in the fasted small intestine - a PEARRL review.

Autor: O'Dwyer PJ; Pion Inc. (UK) Ltd., Forest Row, East Sussex, UK.; Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Zografou, Greece., Litou C; Institute of Pharmaceutical Technology, Goethe University, Frankfurt am Main, Germany., Box KJ; Pion Inc. (UK) Ltd., Forest Row, East Sussex, UK., Dressman JB; Institute of Pharmaceutical Technology, Goethe University, Frankfurt am Main, Germany., Kostewicz ES; Institute of Pharmaceutical Technology, Goethe University, Frankfurt am Main, Germany., Kuentz M; University of Applied Sciences and Arts Northwestern Switzerland, Muttenz, Switzerland., Reppas C; Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Zografou, Greece.

Publikováno v: The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2019 Apr; Vol. 71 (4), pp. 536-556. Date of Electronic Publication: 2018 Jun 28.

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Akademický článek

Model-Based Analysis of Biopharmaceutic Experiments To Improve Mechanistic Oral Absorption Modeling: An Integrated in Vitro in Vivo Extrapolation Perspective Using Ketoconazole as a Model Drug.

Autor: Pathak SM; Simcyp Limited (A Certara Company) , Blades Enterprise Centre, John Street, Sheffield, S2 4SU, United Kingdom., Ruff A; Department of Pharmaceutical Technology, Johann Wolfgang Goethe University , Max-von-Laue-Strasse 9, Frankfurt am Main 60438, Germany., Kostewicz ES; Department of Pharmaceutical Technology, Johann Wolfgang Goethe University , Max-von-Laue-Strasse 9, Frankfurt am Main 60438, Germany., Patel N; Simcyp Limited (A Certara Company) , Blades Enterprise Centre, John Street, Sheffield, S2 4SU, United Kingdom., Turner DB; Simcyp Limited (A Certara Company) , Blades Enterprise Centre, John Street, Sheffield, S2 4SU, United Kingdom., Jamei M; Simcyp Limited (A Certara Company) , Blades Enterprise Centre, John Street, Sheffield, S2 4SU, United Kingdom.

Publikováno v: Molecular pharmaceutics [Mol Pharm] 2017 Dec 04; Vol. 14 (12), pp. 4305-4320. Date of Electronic Publication: 2017 Aug 25.

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Akademický článek

Evaluating the predictability of the in vitro transfer model and in vivo rat studies as a surrogate to investigate the supersaturation and precipitation behaviour of different Albendazole formulations for humans.

Autor: Ruff A; Institute of Pharmaceutical Technology, Goethe University, Max-von-Laue-Str. 9, 60438 Frankfurt am Main, Germany., Holm R; Drug Product Development, Janssen Research and Development, Johnson & Johnson, Turnhoutseweg 30, 2340 Beerse, Belgium., Kostewicz ES; Institute of Pharmaceutical Technology, Goethe University, Max-von-Laue-Str. 9, 60438 Frankfurt am Main, Germany. Electronic address: kostewicz@em.uni-frankfurt.de.

Publikováno v: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2017 Jul 15; Vol. 105, pp. 108-118. Date of Electronic Publication: 2017 May 01.

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Akademický článek

Prediction of Ketoconazole absorption using an updated in vitro transfer model coupled to physiologically based pharmacokinetic modelling.

Autor: Ruff A; Institute of Pharmaceutical Technology, Goethe University, Frankfurt/Main, Germany., Fiolka T; Institute of Pharmaceutical Technology, Goethe University, Frankfurt/Main, Germany., Kostewicz ES; Institute of Pharmaceutical Technology, Goethe University, Frankfurt/Main, Germany. Electronic address: kostewicz@em.uni-frankfurt.de.

Publikováno v: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2017 Mar 30; Vol. 100, pp. 42-55. Date of Electronic Publication: 2016 Dec 21.

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Akademický článek

Lipidic dispersion to reduce food dependent oral bioavailability of fenofibrate: In vitro, in vivo and in silico assessments.

Autor: O'Shea JP; Pharmacodelivery Group, School of Pharmacy, University College Cork, Ireland., Faisal W; Faculty of Pharmacy, Minia University, Egypt., Ruane-O'Hora T; Department of Physiology, University College Cork, Ireland., Devine KJ; Pharmacodelivery Group, School of Pharmacy, University College Cork, Ireland., Kostewicz ES; Institut für Pharmazeutische Technologie, Goethe Universität, Frankfurt am Main, Germany., O'Driscoll CM; Pharmacodelivery Group, School of Pharmacy, University College Cork, Ireland., Griffin BT; Pharmacodelivery Group, School of Pharmacy, University College Cork, Ireland. Electronic address: brendan.griffin@ucc.ie.

Publikováno v: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2015 Oct; Vol. 96, pp. 207-16. Date of Electronic Publication: 2015 Jul 26.

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