Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kostas Savvatis"'
Autor:
Kapka Miteva, Marion Haag, Jun Peng, Kostas Savvatis, Peter Moritz Becher, Martina Seifert, Katrin Warstat, Dirk Westermann, Jochen Ringe, Michael Sittinger, Heinz-Peter Schultheiss, Carsten Tschöpe, Sophie Van Linthout
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28513 (2011)
BACKGROUND: Under conventional heart failure therapy, inflammatory cardiomyopathy typically has a progressive course, indicating a need for alternative therapeutic strategies to improve long-term outcomes. We recently isolated and identified novel ca
Externí odkaz:
https://doaj.org/article/158a04c850794e91bccf5e4e27c364d4
Autor:
Vino Vivekanandam, Natalie James, Roope Männikkö, Richa Sud, Emma Matthews, Doreen Fialho, Enrico Flossmann, Kostas Savvatis, Michael G. Hanna, Thomas D Gossios, K. Suetterlin
Publikováno v:
Journal of neuromuscular diseases. 8(1)
Andersen-Tawil syndrome (ATS) is a rare autosomal dominant neuromuscular disorder due to mutations in the KCNJ2 gene. The classical phenotype of ATS consists of a triad of periodic paralysis, cardiac conduction abnormalities and dysmorphic features.
Autor:
Alexandros, Protonotarios, Eleanor, Wicks, Michael, Ashworth, Edward, Stephenson, Oliver, Guttmann, Kostas, Savvatis, Neha, Sekhri, Saidi A, Mohiddin, Petros, Syrris, Leon, Menezes, Perry, Elliott
Publikováno v:
International journal of cardiology. 284
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a heritable heart muscle disease that causes sudden cardiac death in the young. Inflammatory myocardial infiltrates have been described at autopsy and on biopsy, but there are few data on the
Autor:
Carsten Tschöpe, Irene Müller, Yu Xia, Christin Zietsch, Kostas Savvatis, Dirk Lassner, Uwe Kühl, Heinz-Peter Schultheiss, Burkert Pieske, Sophie Van Linthout
Publikováno v:
Circulation. 132
Introduction: Nucleotide binding oligomerization domain 2 (NOD2) is a cytoplasmatic pattern recognition receptor belonging to the NOD-like receptor family, which is part of the innate immune system. Hypothesis: Since NOD2 recognises ssRNA and Coxsack
Autor:
Robert Schur, Heinz-Peter Schultheiss, Mathias Grüger, Wolfgang Poller, Kostas Savvatis, Zehra Karadeniz, Alexander Jenke, Carsten Röger, Ulf Landmesser, Carsten Skurk, Luise Holzhauser
Publikováno v:
Physiological Reports
Adiponectin (APN) is a multifunctional adipocytokine that inhibits myocardial fibrosis, dilatation, and left ventricular (LV) dysfunction after myocardial infarction (MI). Coxsackievirus B3 (CVB3) myocarditis is associated with intense extracellular
Autor:
Luise Holzhauser, Alexander Jenke, Kostas Savvatis, Mathias Grueger, Robert Schur, Diana Lindner, Dirk Westermann, Wolfgang Poller, Heinz-Peter Schultheiss, Carsten Skurk
Publikováno v:
Circulation. 130
Introduction: Transdifferentiation of cardiac fibroblasts into myofibroblasts regulated by TGFβ/SMAD3 signaling is a major mechanism of scar formation and adverse remodeling following myocardial infarction. Hypothesis: We hypothesized that the trans
Autor:
Felix Berger, Titus Kuehne, Daniel Messroghli, Elena Kaschina, Thore Dietrich, Sarah Nordmeyer, Darach O h-Ici, Kostas Savvatis, Christoph Klein, Olaf Dirsch
Publikováno v:
Circulation. Cardiovascular imaging. 4(6)
Background— The concentration of gadopentetate dimeglumine in myocardium and blood can be assessed from T1 measurements and can be used to calculate the extracellular volume (ECV) of the myocardium. We hypothesized that diffuse myocardial fibrosis