Zobrazeno 1 - 10
of 1 284
pro vyhledávání: '"Kostakis, P."'
Publikováno v:
tripleC: Communication, Capitalism & Critique, Vol 22, Iss 2, Pp 620-629 (2024)
This article addresses Anna Tsing’s critique of capitalist scalability by introducing the concept of “cosmolocal scalability” as an alternative to approaches that prioritise “scale-at-all-costs.” Cosmolocal scalability challenges the idea o
Externí odkaz:
https://doaj.org/article/150db043626140ac8e15239b48408e6b
Autor:
Aman Mebrahtu, Ida Laurén, Rosanne Veerman, Gözde Güclüler Akpinar, Martin Lord, Alexandros Kostakis, Juan Astorga-Wells, Leif Dahllund, Anders Olsson, Oscar Andersson, Jonathan Persson, Helena Persson, Pierre Dönnes, Johan Rockberg, Sara Mangsbo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Current antibody-based immunotherapy depends on tumor antigen shedding for proper T cell priming. Here we select a novel human CD40 agonistic drug candidate and generate a bispecific antibody, herein named BiA9*2_HF, that allows for rapid an
Externí odkaz:
https://doaj.org/article/d469af897715422a9a5f977bb3bd08a2
Autor:
Konstantina Papastavropoulou, Anastasia Koupa, Evangelia Kritikou, Marios Kostakis, Sofia Dervisoglou, Andreas Roussos, Dionysios Perdikis, Nikolaos S. Thomaidis, Emel Oz, Fatih Oz, Charalampos Proestos, Haizhou Wu
Publikováno v:
Food Chemistry: X, Vol 24, Iss , Pp 101838- (2024)
Science and food industry must strive to ensure and improve edible insect's benefits, and especially their safety and nutritional value. This study investigated how various food substrates used in the rearing of Tenebrio molitor larvae influence thei
Externí odkaz:
https://doaj.org/article/b34d37a112da453da70172c70c7d9934
Autor:
Vaia-Argyro Bakalakou, Barbara Mavroidi, Amalia D. Kalampaliki, Béatrice Josselin, Stéphane Bach, Alexios-Leandros Skaltsounis, Panagiotis Marakos, Nicole Pouli, Maria Pelecanou, Vassilios Myrianthopoulos, Sandrine Ruchaud, Ioannis K. Kostakis
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 12, Iss , Pp 100222- (2024)
Externí odkaz:
https://doaj.org/article/796a47e7bf3d4ea9afa8b3e139831007
Autor:
Vaia-Argyro Bakalakou, Barbara Mavroidi, Amalia D. Kalampaliki, Béatrice Josselin, Stéphane Bach, Alexios-Leandros Skaltsounis, Panagiotis Marakos, Nicole Pouli, Maria Pelecanou, Vassilios Myrianthopoulos, Sandrine Ruchaud, Ioannis K. Kostakis
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 12, Iss , Pp 100193- (2024)
In the current study, we designed, synthesized, and characterized a series of substituted pyrazolo[4,3-c]pyrazoles. These novel compounds were evaluated in vitro for their inhibitory activity over a panel of protein kinases to determine their potenti
Externí odkaz:
https://doaj.org/article/eb0021815ee9431cabe5edd011eff369
Publikováno v:
Cleaner Production Letters, Vol 7, Iss , Pp 100065- (2024)
Environmental deterioration is a significant and multi-dimensional issue that concerns the modern world. During the last decades, research has been conducted to address this argument, intending to provide holistic policies that drive sustainable deve
Externí odkaz:
https://doaj.org/article/2ecd870c0e2747c0bd95df253cb7c535
Autor:
Lewis P. Bailey, Robert M. Dorrell, Ina Kostakis, David McKee, Dan Parsons, Jon Rees, James Strong, Stephen Simmons, Rodney Forster
Publikováno v:
Frontiers in Earth Science, Vol 12 (2024)
Offshore wind farms are becoming an increasingly common feature in the marine environment as a renewable energy source. There is a growing body of evidence on the effects of wind farms on the seabed and its organisms. However, an important and unders
Externí odkaz:
https://doaj.org/article/86ca125d2d214545af4f336fd9dff166
Autor:
Eleftheria A. Georgiou, Konstantinos Paraskevas, Christina Koutra, Leentje Persoons, Dominique Schols, Steven De Jonghe, Ioannis K. Kostakis
Publikováno v:
Molecules, Vol 29, Iss 23, p 5549 (2024)
Thirteen new 4,7-disubstituted pyrimido[4,5-d]pyrimidines were synthesized via a straightforward methodology starting from thiourea. The anti-proliferative activity of these compounds was evaluated across a diverse panel of eight cancer cell lines, w
Externí odkaz:
https://doaj.org/article/08e8591e13994e819402788dc662fbb5
Autor:
Nikolaos V. Angelis, Efthymios Paronis, Georgia Sarikaki, Antonios Kyriakopoulos, Anna Agapaki, Pigi-Maria Niotopoulou, Christina C. Knai, Pavlos Alexakos, Odyssefs Liagkas, Konstantinos F. Mavreas, Constantin N. Baxevanis, Alexios-Leandros Skaltsounis, Ourania E. Tsitsilonis, Ioannis K. Kostakis
Publikováno v:
Antioxidants, Vol 13, Iss 11, p 1422 (2024)
Inflammation is a key process in the pathophysiology of various diseases, with macrophages playing a central role in the inflammatory response. This study investigates the anti-inflammatory potential of a newly synthesized analog of oleuropein (OP),
Externí odkaz:
https://doaj.org/article/19768f9ad8b743d68624dd471286ba8f
Autor:
Filio Petsini, Maria Detopoulou, Maria Choleva, Ioannis K. Kostakis, Elizabeth Fragopoulou, Smaragdi Antonopoulou
Publikováno v:
Molecules, Vol 29, Iss 22, p 5419 (2024)
Platelet-activating factor (PAF) is a potent lipid mediator, involved in thrombosis, inflammation, and atherosclerosis. The protective effect of wine and olive oil against atherosclerotic diseases is largely attributed to their phenolic compounds and
Externí odkaz:
https://doaj.org/article/8b390db61b4d41b98c1e3a01e6c923a7