Zobrazeno 1 - 10
of 3 949
pro vyhledávání: '"Kost, P."'
Autor:
Ermatov, Arthur, Kost, Melisande, Yin, Xin, Butler, Paul, Dass, Mihir, Sharp, Ian D., Liedl, Tim, Bein, Thomas, Posnjak, Gregor
While DNA origami is a powerful bottom-up fabrication technique, the physical and chemical stability of DNA nanostructures is generally limited to aqueous buffer conditions. Wet chemical silicification can stabilise these structures but does not add
Externí odkaz:
http://arxiv.org/abs/2410.13393
A first-principle single-object model is proposed for pedestrian tracking. It is assumed that the extent of the moving object can be described via known statistics in 3D, such as pedestrian height. The proposed model thus need not constrain the objec
Externí odkaz:
http://arxiv.org/abs/2403.11978
Publikováno v:
Phys. Rev. D 109, 103037 (2024)
Collective neutrino oscillations are typically studied using the lowest-order quantum kinetic equation, also known as the mean-field approximation. However, some recent quantum many-body simulations suggest that quantum entanglement among neutrinos m
Externí odkaz:
http://arxiv.org/abs/2402.05022
Autor:
Schulhoff, Sander, Pinto, Jeremy, Khan, Anaum, Bouchard, Louis-François, Si, Chenglei, Anati, Svetlina, Tagliabue, Valen, Kost, Anson Liu, Carnahan, Christopher, Boyd-Graber, Jordan
Large Language Models (LLMs) are deployed in interactive contexts with direct user engagement, such as chatbots and writing assistants. These deployments are vulnerable to prompt injection and jailbreaking (collectively, prompt hacking), in which mod
Externí odkaz:
http://arxiv.org/abs/2311.16119
Autor:
Davinder Sharma, Raz Avni, Juan Gutierrez-Gonzalez, Rakesh Kumar, Hanan Sela, Manas Ranjan Prusty, Arava Shatil-Cohen, István Molnár, Kateřina Holušová, Mahmoud Said, Jaroslav Doležel, Eitan Millet, Sofia Khazan-Kost, Udi Landau, Gerit Bethke, Or Sharon, Smadar Ezrati, Moshe Ronen, Oxana Maatuk, Tamar Eilam, Jacob Manisterski, Pnina Ben-Yehuda, Yehoshua Anikster, Oadi Matny, Brian J. Steffenson, Martin Mascher, Helen J. Brabham, Matthew J. Moscou, Yong Liang, Guotai Yu, Brande B. H. Wulff, Gary Muehlbauer, Anna Minz-Dub, Amir Sharon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Nucleotide-binding leucine-rich repeat (NLR) disease resistance genes typically confer resistance against races of a single pathogen. Here, we report that Yr87/Lr85, an NLR gene from Aegilops sharonensis and Aegilops longissima, confers resi
Externí odkaz:
https://doaj.org/article/32be3c80d53649dea1fb823688effbc9
Autor:
Xue Yang, Zexuan Liu, Weiwei Tang, Uday P. Pratap, Alexia B. Collier, Kristin A. Altwegg, Rahul Gopalam, Xiaonan Li, Yaxia Yuan, Daohong Zhou, Zhao Lai, Yidong Chen, Gangadhara R. Sareddy, Philip T. Valente, Edward R. Kost, Suryavathi Viswanadhapalli, Ratna K. Vadlamudi
Publikováno v:
Molecular Oncology, Vol 18, Iss 9, Pp 2136-2156 (2024)
Endometrial carcinoma (ECa) is the fourth most common cancer among women. The oncogene PELP1 is frequently overexpressed in a variety of cancers, including ECa. We recently generated SMIP34, a small‐molecule inhibitor of PELP1 that suppresses PELP1
Externí odkaz:
https://doaj.org/article/004752a72a024ab7b87a815d9b033c3e
Autor:
Sophia Zoungas, Chris Moran, Andrea J. Curtis, Simone Spark, Zachary Flanagan, Lawrence Beilin, Trevor T.‐J. Chong, Geoffrey C. Cloud, Ingrid Hopper, Alissia Kost, John J. McNeil, Stephen J. Nicholls, Christopher M. Reid, Joanne Ryan, Andrew M. Tonkin, Stephanie Ward, Anthony S. Wierzbicki, Rory Wolfe, Zhen Zhou, Mark R. Nelson
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 22 (2024)
Background The risk–benefit balance of statin use in healthy older people is uncertain. We describe the baseline characteristics of the STAREE (Statins in Reducing Events in the Elderly) trial, which is a randomized, double‐blind, placebo‐contr
Externí odkaz:
https://doaj.org/article/0f943baeac03416d90ac362724f0bb84
Autor:
Behnam Ebrahimi, Suryavathi Viswanadhapalli, Uday P. Pratap, Gopalam Rahul, Xue Yang, Prabhakar Pitta Venkata, Viktor Drel, Bindu Santhamma, Swapna Konda, Xiaonan Li, Alondra Lee Rodriguez Sanchez, Hui Yan, Gangadhara R. Sareddy, Zhenming Xu, Brij B. Singh, Philip T. Valente, Yidong Chen, Zhao Lai, Manjeet Rao, Edward R. Kost, Tyler Curiel, Rajeshwar R. Tekmal, Hareesh B. Nair, Ratna K. Vadlamudi
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-18 (2024)
Abstract Of all gynecologic cancers, epithelial-ovarian cancer (OCa) stands out with the highest mortality rates. Despite all efforts, 90% of individuals who receive standard surgical and cytotoxic therapy experience disease recurrence. The precise m
Externí odkaz:
https://doaj.org/article/9ac36726d5db494b89c1884b726a9b5c
Autor:
Nitsa Buaron, Antonella Mangraviti, Yuan Wang, Ann Liu, Mariangela Pedone, Eric Sankey, Itay Adar, Abraham Nyska, Riki Goldbart, Tamar Traitel, Henry Brem, Betty Tyler, Joseph Kost
Publikováno v:
Bioengineering & Translational Medicine, Vol 9, Iss 5, Pp n/a-n/a (2024)
Abstract Glioma is one of the most common primary malignant brain tumors. Despite progress in therapeutic approaches, the median survival of patients with glioma remains less than 2 years, generating the need for new therapeutic approaches. Ultrasoun
Externí odkaz:
https://doaj.org/article/ae28d496f2db4d3ca285d515782f95c3
Autor:
Rakhi Jain, Charles P. Kost II
Publikováno v:
The Pinnacle, Vol 2, Iss 2 (2024)
Outsourcing is a strategic initiative that various organizations use to reduce operational costs and increase market competitiveness. However, these organizations have observed low productivity, underutilized capacity, and low profitability from qual
Externí odkaz:
https://doaj.org/article/501b52ac9a0d4e2488d3c62917c12568