Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Kosovrasti K"'
Autor:
Lockbaum GJ; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, 01605, United States., Rusere LN; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, 01605, United States., Henes M; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, 01605, United States., Kosovrasti K; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, 01605, United States., Rao DN; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, 01605, United States., Spielvogel E; Department of Biochemistry and Biophysics, And the UNC Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, United States., Lee SK; Department of Biochemistry and Biophysics, And the UNC Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, United States., Nalivaika EA; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, 01605, United States., Swanstrom R; Department of Biochemistry and Biophysics, And the UNC Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, United States., Yilmaz NK; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, 01605, United States., Schiffer CA; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, 01605, United States. Electronic address: Celia.Schiffer@umassmed.edu., Ali A; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, 01605, United States. Electronic address: Akbar.Ali@umassmed.edu.
Publikováno v:
European journal of medicinal chemistry [Eur J Med Chem] 2023 Sep 05; Vol. 257, pp. 115501. Date of Electronic Publication: 2023 May 18.
Autor:
Spielvogel E; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, United States.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, United States., Lee SK; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, United States., Zhou S; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, United States., Lockbaum GJ; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Medical School, Worcester, United States., Henes M; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Medical School, Worcester, United States., Sondgeroth A; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, United States.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, United States., Kosovrasti K; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Medical School, Worcester, United States., Nalivaika EA; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Medical School, Worcester, United States., Ali A; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Medical School, Worcester, United States., Yilmaz NK; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Medical School, Worcester, United States., Schiffer CA; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Medical School, Worcester, United States., Swanstrom R; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, United States.; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, United States.
Publikováno v:
ELife [Elife] 2023 Mar 15; Vol. 12. Date of Electronic Publication: 2023 Mar 15.
Autor:
Spielvogel, E., Schiffer, C.A., Nalivaika, E.A., Yilmaz, N.K., Ali, A., Kosovrasti, K., Lockbaum, G.J., Swanstrom, R., Henes, M., Rusere, L.N., Lee, S.-K.
A structure-guided design strategy was used to improve the resistance profile of HIV-1 protease inhibitors by optimizing hydrogen bonding and van der Waals interactions with the protease while staying within the substrate envelope. Stereoisomers of 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::901ac0a16ec07b478adeecaf9355336e
Autor:
Zephyr J; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, United States., Nageswara Rao D; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, United States., Vo SV; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, United States., Henes M; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, United States., Kosovrasti K; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, United States., Matthew AN; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, United States., Hedger AK; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, United States., Timm J; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, United States., Chan ET; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, United States., Ali A; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, United States., Kurt Yilmaz N; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, United States., Schiffer CA; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, United States. Electronic address: Celia.Schiffer@umassmed.edu.
Publikováno v:
Journal of molecular biology [J Mol Biol] 2022 May 15; Vol. 434 (9), pp. 167503. Date of Electronic Publication: 2022 Feb 17.
Autor:
Lockbaum GJ; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States., Henes M; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States., Talledge N; Institute for Molecular Virology, Masonic Cancer Center, University of Minnesota - Twin Cities, Minneapolis, Minnesota 55455, United States., Rusere LN; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States., Kosovrasti K; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States., Nalivaika EA; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States., Somasundaran M; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States., Ali A; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States., Mansky LM; Institute for Molecular Virology, Masonic Cancer Center, University of Minnesota - Twin Cities, Minneapolis, Minnesota 55455, United States., Kurt Yilmaz N; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States., Schiffer CA; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States.
Publikováno v:
ACS chemical biology [ACS Chem Biol] 2021 Mar 19; Vol. 16 (3), pp. 529-538. Date of Electronic Publication: 2021 Feb 23.
Autor:
Ojha, Durbadal1 (AUTHOR), Hill, Collin S.2 (AUTHOR), Zhou, Shuntai2,3 (AUTHOR), Evans, Alyssa1 (AUTHOR), Leung, Jacqueline M.4 (AUTHOR), Schneider, Christine A.1 (AUTHOR), Amblard, Franck5 (AUTHOR), Woods, Tyson A.1 (AUTHOR), Schinazi, Raymond F.5 (AUTHOR), Baric, Ralph S.3,6 (AUTHOR), Peterson, Karin E.1 (AUTHOR) petersonka@niaid.nih.gov, Swanstrom, Ronald2,7 (AUTHOR) risunc@med.unc.edu
Publikováno v:
PLoS Pathogens. 9/30/2024, Vol. 20 Issue 9, p1-20. 20p.
Autor:
McGraw, Aidan1 (AUTHOR) amcgraw@american.edu, Hillmer, Grace1 (AUTHOR) gh2297a@american.edu, Medehincu, Stefania M.1 (AUTHOR) sm4872a@american.edu, Hikichi, Yuta2 (AUTHOR) yuta.hikichi@nih.gov, Gagliardi, Sophia1 (AUTHOR) sg1978a@american.edu, Narayan, Kedhar1 (AUTHOR) kn0119a@american.edu, Tibebe, Hasset1 (AUTHOR) ht8146a@american.edu, Marquez, Dacia1 (AUTHOR) dm6732a@american.edu, Mei Bose, Lilia1 (AUTHOR) lb9210a@american.edu, Keating, Adleigh1 (AUTHOR) akeating@american.edu, Izumi, Coco1 (AUTHOR) cizumi@american.edu, Peese, Kevin3 (AUTHOR) kevin.m.peese@viivhealthcare.com, Joshi, Samit3 (AUTHOR) samit.r.joshi@viivhealthcare.com, Krystal, Mark3 (AUTHOR) mark.r.krystal@viivhealthcare.com, DeCicco-Skinner, Kathleen L.1 (AUTHOR) decicco@american.edu, Freed, Eric O.2 (AUTHOR) efreed@mail.nih.gov, Sardo, Luca3 (AUTHOR) luca.x.sardo@viivhealthcare.com, Izumi, Taisuke1,4 (AUTHOR) luca.x.sardo@viivhealthcare.com
Publikováno v:
Viruses (1999-4915). Sep2024, Vol. 16 Issue 9, p1423. 30p.
Autor:
Azzolino, Vincent N.1 (AUTHOR) vincent.azzolino@umassmed.edu, Shaqra, Ala M.1 (AUTHOR), Ali, Akbar1 (AUTHOR), Kurt Yilmaz, Nese1 (AUTHOR), Schiffer, Celia A.1 (AUTHOR) celia.schiffer@umassmed.edu
Publikováno v:
Viruses (1999-4915). Sep2024, Vol. 16 Issue 9, p1419. 17p.
Autor:
Rusere LN; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States., Lockbaum GJ; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States., Henes M; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States., Lee SK; Department of Biochemistry and Biophysics, and the UNC Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States., Spielvogel E; Department of Biochemistry and Biophysics, and the UNC Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States., Rao DN; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States., Kosovrasti K; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States., Nalivaika EA; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States., Swanstrom R; Department of Biochemistry and Biophysics, and the UNC Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States., Kurt Yilmaz N; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States., Schiffer CA; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States., Ali A; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2020 Aug 13; Vol. 63 (15), pp. 8296-8313. Date of Electronic Publication: 2020 Aug 03.
Autor:
Matthew AN; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Zephyr J; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Nageswara Rao D; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Henes M; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Kamran W; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Kosovrasti K; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Hedger AK; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Lockbaum GJ; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Timm J; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Ali A; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Kurt Yilmaz N; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA Nese.KurtYilmaz@umassmed.edu Celia.Schiffer@umassmed.edu., Schiffer CA; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA Nese.KurtYilmaz@umassmed.edu Celia.Schiffer@umassmed.edu.
Publikováno v:
MBio [mBio] 2020 Mar 31; Vol. 11 (2). Date of Electronic Publication: 2020 Mar 31.