Human melanoma‐cell metabolic profiling: Identification of novel biomarkers indicating metastasis

Autor: Kosmopoulou, M. Giannopoulou, A.F. Iliou, A. Benaki, D. Panagiotakis, A. Velentzas, A.D. Konstantakou, E.G. Papassideri, I.S. Mikros, E. Stravopodis, D.J. Gikas, E.

Melanoma is the most aggressive type of skin cancer, leading to metabolic rewiring and enhancement of metastatic transformation. Efforts to improve its early and accurate diagnosis are largely based on preclinical models and especially cell lines. He

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::471497f02e7698b1d3c906c45744bd87
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2981022

Cyclobutanone mimics of intermediates in metallo-β-lactamase catalysis

Autor: Abboud, M, Kosmopoulou, M, Krismanich, A, Johnson, J, Hinchliffe, P, Brem, J, Claridge, T, Spencer, J, Schofield, C, Dmitrienko, G

Publikováno v: Chemistry (Weinheim an Der Bergstrasse, Germany)
Abboud, M I, Kosmopoulou, M, Krismanich, A P, Johnson, J W, Hinchliffe, P, Brem, J, Claridge, T D W, Spencer, J, Schofield, C J & Dmitrienko, G I 2017, ' Cyclobutanone Mimics of Intermediates in Metallo-β-Lactamase Catalysis ', Chemistry-A European Journal . https://doi.org/10.1002/chem.201705886

The most important resistance mechanism to β-lactam antibiotics involves hydrolysis by two β-lactamase categories: the nucleophilic serine and the metallo-β-lactamases (SBLs and MBLs, respectively). Cyclobutanones are hydrolytically stable β-lact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::10a0ca3026d4e721b4e6f0743792d18b
http://ora.ox.ac.uk/objects/uuid:

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Crystallographic studies on two bioisosteric analogues, N-acetyl-beta-D-glucopyranosylamine and N-trifluoroacetyl-beta-D-glucopyranosylamine, potent inhibitors of muscle glycogen phosphorylase

Autor: Anagnostou, E., Kosmopoulou, M. N., Chrysina, Evangelia D., Leonidas, D. D., Hadjiloi, T., Tiraidis, C., Zographos, S. E., Gyorgydeak, Z., Somsak, L., Docsa, T., Gergely, P., Kolisis, Fragiskos N., Oikonomakos, Nikos G.

Publikováno v: Bioorganic & Medicinal Chemistry 14:1(Jan2006):181-189

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1457::1de82d1e7ff495b9a88c2ff85519d40c
http://helios-eie.ekt.gr/EIE/handle/10442/8120

Binding of N-acetyl-N '-beta-D-glucopyranosyl urea and N-benzoyl-N '-beta-D-glucopyranosyl urea to glycogen phosphorylase b - Kinetic and crystallographic studies

Autor: Oikonomakos, Nikos G., Kosmopoulou, M., Zographos, Spyros E., Leonidas, Demetres D., Chrysina, Evangelia D., Somsak, U., Nagy, V., Praly, J. P., Docsa, T., Toth, A., Gergely, P.

Publikováno v: European Journal of Biochemistry 269:6(Mar2002):1684-1696

Journal URL: http://www.blackwell-synergy.com/loi/ejb

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http://helios-eie.ekt.gr/EIE/handle/10442/2692