Isolating cells from adult murine brain for validation of cell-type specific cre-mediated deletion

Autor: Kosior, Natalia, Petkau, Terri L., Connolly, Colúm, Lu, Ge, Leavitt, Blair R.

Publikováno v: In Journal of Neuroscience Methods 1 December 2019 328

Selective depletion of microglial progranulin in mice is not sufficient to cause neuronal ceroid lipofuscinosis or neuroinflammation.

Autor: Petkau, Terri L.¹, Kosior, Natalia¹, de Asis, Kathleen¹, Connolly, Colúm¹, Leavitt, Blair R.^1,2,3 bleavitt@cmmt.ubc.ca

Publikováno v: Journal of Neuroinflammation. 11/17/2017, Vol. 14, p1-11. 11p.

Additional file 1: Figure S1. of Selective depletion of microglial progranulin in mice is not sufficient to cause neuronal ceroid lipofuscinosis or neuroinflammation

Autor: Petkau, Terri, Kosior, Natalia, Asis, Kathleen De, Colúm Connolly, Leavitt, Blair

Progranulin mRNA, intracellular, and secreted protein levels correlate in primary microglia cultures. (A) Progranulin mRNA levels were reduced by approximately 50% in Het cultures compared to WT cultures and not detectable in GrnKO cultures. N = 2–

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264eb8fe5c9c4c46f6a91abc7f041877

Murine Models of Huntington's Disease for Evaluating Therapeutics.

Autor: Kosior N; Centre for Molecular Medicine and Therapeutics, and Department of Medical Genetics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada., Leavitt BR; Centre for Molecular Medicine and Therapeutics, and Department of Medical Genetics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada. bleavitt@cmmt.ubc.ca.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2018; Vol. 1780, pp. 179-207.