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Inhibition of heme-thiolate monooxygenase CYP1B1 prevents hepatic stellate cell activation and liver fibrosis by accumulating trehalose.

Autor: Tung HC; Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Kim JW; Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Zhu J; Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Li S; Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Yan J; Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Liu Q; Center for Molecular Toxicology and Carcinogenesis, Department of Veterinary and Biomedical Sciences, Pennsylvania State University, University Park, PA 16802, USA., Koo I; Center for Molecular Toxicology and Carcinogenesis, Department of Veterinary and Biomedical Sciences, Pennsylvania State University, University Park, PA 16802, USA., Koshkin SA; Center for Molecular Toxicology and Carcinogenesis, Department of Veterinary and Biomedical Sciences, Pennsylvania State University, University Park, PA 16802, USA., Hao F; Center for Molecular Toxicology and Carcinogenesis, Department of Veterinary and Biomedical Sciences, Pennsylvania State University, University Park, PA 16802, USA., Zhong G; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA 98195, USA., Xu M; Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Wang Z; Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Wang J; Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Huang Y; Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Xi Y; Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Cai X; Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Xu P; Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Ren S; Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Higashiyama T; Research and Development Division, Hayashibara Co., Ltd, Okayama 7028006, Japan., Gonzalez FJ; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Li S; Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Isoherranen N; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA 98195, USA., Yang D; Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Ma X; Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Patterson AD; Center for Molecular Toxicology and Carcinogenesis, Department of Veterinary and Biomedical Sciences, Pennsylvania State University, University Park, PA 16802, USA., Xie W; Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA.; Department of Pharmacology & Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA.

Publikováno v: Science translational medicine [Sci Transl Med] 2024 Sep 25; Vol. 16 (766), pp. eadk8446. Date of Electronic Publication: 2024 Sep 25.

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Isolation and Characterization of Human Colon Adenocarcinoma Stem-Like Cells Based on the Endogenous Expression of the Stem Markers.

Autor: Koshkin SA; Institute of Cytology of the Russian Academy of Science, 194064 St-Petersburg, Russia.; Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, 1015 Walnut Street, Ste. 1024, Philadelphia, PA 19107, USA., Anatskaya OV; Institute of Cytology of the Russian Academy of Science, 194064 St-Petersburg, Russia., Vinogradov AE; Institute of Cytology of the Russian Academy of Science, 194064 St-Petersburg, Russia., Uversky VN; Department of Molecular Medicine and USF Health Byrd Alzheimer's Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA., Dayhoff GW 2nd; Department of Chemistry, College of Art and Sciences, University of South Florida, Tampa, FL 33620, USA., Bystriakova MA; Institute of Cytology of the Russian Academy of Science, 194064 St-Petersburg, Russia., Pospelov VA; Institute of Cytology of the Russian Academy of Science, 194064 St-Petersburg, Russia., Tolkunova EN; Institute of Cytology of the Russian Academy of Science, 194064 St-Petersburg, Russia.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Apr 28; Vol. 22 (9). Date of Electronic Publication: 2021 Apr 28.

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Akademický článek

Prebiotic Syntheses Under Shock in the Water - Formamide - Potassium Bicarbonate - Sodium Hydroxide System.

Autor: Shtyrlin VG; A.M. Butlerov Chemistry Institute, Kazan Federal University, Kremlevskaya St., 18, Kazan, Russian Federation, 420008. Valery.Shtyrlin@gmail.com., Borissenok VA; Sarov Physical Technical Institute, National Research Nuclear University 'MEPhI' (Moscow Engineering Physics Institute), Dukhov St., 6, Sarov, Russian Federation, 607184., Serov NY; A.M. Butlerov Chemistry Institute, Kazan Federal University, Kremlevskaya St., 18, Kazan, Russian Federation, 420008., Simakov VG; Sarov Physical Technical Institute, National Research Nuclear University 'MEPhI' (Moscow Engineering Physics Institute), Dukhov St., 6, Sarov, Russian Federation, 607184.; Russian Federal Nuclear Center, All-Russian Research Institute of Experimental Physics, Mir Pr., 37, Sarov, Russian Federation, 607188., Bragunets VA; Russian Federal Nuclear Center, All-Russian Research Institute of Experimental Physics, Mir Pr., 37, Sarov, Russian Federation, 607188., Trunin IR; Sarov Physical Technical Institute, National Research Nuclear University 'MEPhI' (Moscow Engineering Physics Institute), Dukhov St., 6, Sarov, Russian Federation, 607184.; Russian Federal Nuclear Center, All-Russian Research Institute of Experimental Physics, Mir Pr., 37, Sarov, Russian Federation, 607188., Tereshkina IA; Sarov Physical Technical Institute, National Research Nuclear University 'MEPhI' (Moscow Engineering Physics Institute), Dukhov St., 6, Sarov, Russian Federation, 607184.; Russian Federal Nuclear Center, All-Russian Research Institute of Experimental Physics, Mir Pr., 37, Sarov, Russian Federation, 607188., Koshkin SA; A.M. Butlerov Chemistry Institute, Kazan Federal University, Kremlevskaya St., 18, Kazan, Russian Federation, 420008., Bukharov MS; A.M. Butlerov Chemistry Institute, Kazan Federal University, Kremlevskaya St., 18, Kazan, Russian Federation, 420008., Gilyazetdinov EM; A.M. Butlerov Chemistry Institute, Kazan Federal University, Kremlevskaya St., 18, Kazan, Russian Federation, 420008., Shestakov EE; Sarov Physical Technical Institute, National Research Nuclear University 'MEPhI' (Moscow Engineering Physics Institute), Dukhov St., 6, Sarov, Russian Federation, 607184.; Russian Federal Nuclear Center, All-Russian Research Institute of Experimental Physics, Mir Pr., 37, Sarov, Russian Federation, 607188., Sirotkina AG; Sarov Physical Technical Institute, National Research Nuclear University 'MEPhI' (Moscow Engineering Physics Institute), Dukhov St., 6, Sarov, Russian Federation, 607184., Zakharov AV; A.M. Butlerov Chemistry Institute, Kazan Federal University, Kremlevskaya St., 18, Kazan, Russian Federation, 420008.

Publikováno v: Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life [Orig Life Evol Biosph] 2019 Jun; Vol. 49 (1-2), pp. 1-18. Date of Electronic Publication: 2019 Apr 19.

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Akademický článek

Synthesis of a new quaternary phosphonium salt: NMR study of the conformational structure and dynamics.

Autor: Aganova OV; Institute of Physics, Kazan (Volga Region) Federal University, Kremlevskaya Str., 18, 420008, Kazan, Russia., Galiullina LF; Institute of Physics, Kazan (Volga Region) Federal University, Kremlevskaya Str., 18, 420008, Kazan, Russia., Aganov AV; Institute of Physics, Kazan (Volga Region) Federal University, Kremlevskaya Str., 18, 420008, Kazan, Russia., Shtyrlin NV; Research and Educational Center of Pharmacy, Kazan Federal University, Kazan, 420008, Russia., Pugachev MV; Research and Educational Center of Pharmacy, Kazan Federal University, Kazan, 420008, Russia., Strel'nik AD; Research and Educational Center of Pharmacy, Kazan Federal University, Kazan, 420008, Russia., Koshkin SA; Research and Educational Center of Pharmacy, Kazan Federal University, Kazan, 420008, Russia., Shtyrlin YG; Research and Educational Center of Pharmacy, Kazan Federal University, Kazan, 420008, Russia., Klochkov VV; Institute of Physics, Kazan (Volga Region) Federal University, Kremlevskaya Str., 18, 420008, Kazan, Russia.

Publikováno v: Magnetic resonance in chemistry : MRC [Magn Reson Chem] 2016 Apr; Vol. 54 (4), pp. 320-7. Date of Electronic Publication: 2015 Dec 14.

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