Zobrazeno 1 - 10
of 345
pro vyhledávání: '"Koschak, A"'
Autor:
Thomas Heigl, Michael A. Netzer, Lucia Zanetti, Matthias Ganglberger, Monica L. Fernández-Quintero, Alexandra Koschak
Publikováno v:
Channels, Vol 17, Iss 1 (2023)
ABSTRACTCav1.4 L-type calcium channels are predominantly expressed at the photoreceptor terminals and in bipolar cells, mediating neurotransmitter release. Mutations in its gene, CACNA1F, can cause congenital stationary night-blindness type 2 (CSNB2)
Externí odkaz:
https://doaj.org/article/ef2b99a0abab4d838bb79811b9811fd5
Autor:
Irem Kilicarslan, Lucia Zanetti, Elena Novelli, Christoph Schwarzer, Enrica Strettoi, Alexandra Koschak
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Retinitis Pigmentosa is a genetically heterogeneous, degenerative retinal disorder characterized by gradual dysfunction and death of photoreceptors, first rods and later cones, and progressive blindness. Studies suggested that application of
Externí odkaz:
https://doaj.org/article/c195843478044d28b924edd3054a2ac5
Autor:
Lucia Zanetti, Irem Kilicarslan, Michael Netzer, Norbert Babai, Hartwig Seitter, Alexandra Koschak
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract CaV1.4 L-type calcium channels are predominantly expressed in photoreceptor terminals playing a crucial role for synaptic transmission and, consequently, for vision. Human mutations in the encoding gene are associated with congenital station
Externí odkaz:
https://doaj.org/article/bae152107bcb4000819c34d09136ac31
Akademický článek
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Autor:
Nguyet-Minh Nguyen Le, Sarah Zsák, Bao Le-Vinh, Julian David Friedl, Gergely Kali, Patrick Knoll, Hartwig Wolfram Seitter, Alexandra Koschak, Andreas Bernkop-Schnürch
Publikováno v:
ACS Applied Materials & Interfaces. 14:44981-44991
This study aimed to develop phosphatase-responsive ζ potential converting nanocarriers utilizing polyphosphate-coated cell-penetrating peptide (CPP)-decorated nanoemulsions (NEs) as a novel gene delivery system to retinal cells.Poly-l-lysine (PLL) w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8957ebb9100b04ce0ce32f23ff7c38
https://doi.org/10.1021/acsami.2c11649
https://doi.org/10.1021/acsami.2c11649
Akademický článek
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Autor:
Hartwig Seitter, Jana Obkircher, Patricia Grabher, Julia Hartl, Lucia Zanetti, Uwe Thorsten Lux, Georgios Fotakis, Monica L. Fernández-Quintero, Teresa Kaserer, Alexandra Koschak
Publikováno v:
J Biol Chem
Cavβ subunits are essential for surface expression of voltage-gated calcium channel complexes and crucially modulate biophysical properties like voltage-dependent inactivation. Here, we describe the discovery and characterization of a novel Cavβ(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e0ada4523a5e710cd377086110e9092
https://europepmc.org/articles/PMC10074810/
https://europepmc.org/articles/PMC10074810/
Autor:
Alexandra Koschak, Monica L. Fernández-Quintero, Hartwig Seitter, Marco Ruzza, Thomas Heigl, Lucia Zanetti
Publikováno v:
Pflugers Archiv
Cav1.4 L-type Ca2+ channels are predominantly expressed in retinal neurons, particularly at the photoreceptor terminals where they mediate sustained Ca2+ entry needed for continuous neurotransmitter release at their ribbon synapses. Cav1.4 channel ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c948bff7983ce634eb674e4898eced48
https://doi.org/10.1007/s00424-021-02570-x
https://doi.org/10.1007/s00424-021-02570-x
Autor:
Alexandra Koschak, Amy Lee
Publikováno v:
Voltage-Gated Calcium Channels ISBN: 9783031088803
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3688342bf3b082196a77bbb407c3fb8
https://doi.org/10.1007/978-3-031-08881-0_17
https://doi.org/10.1007/978-3-031-08881-0_17