Stress signalling and fungal pathogenesis in Candida species

Autor: Kos, Iaroslava

Candida albicans and Candida glabrata are major pathogens of humans, causing 8% of all hospital acquired systemic infections worldwide. Moreover, such systemic infections are associated with alarmingly high morbidity and mortality rates. One of the m

Externí odkaz: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.728312

Mechanisms Underlying the Delayed Activation of the Cap1 Transcription Factor in Candida albicans following Combinatorial Oxidative and Cationic Stress Important for Phagocytic Potency

Autor: Kos, Iaroslava, Patterson, Miranda J, Znaidi, Sadri, Kaloriti, Despoina, da Silva Dantas, Alessandra, Herrero-de-Dios, Carmen M, D'Enfert, Christophe, Brown, Alistair J P, Quinn, Janet

Publikováno v: mBio
mBio, American Society for Microbiology, 2016, 7 (2), pp.e00331-16. ⟨10.1128/mBio.00331-16⟩
mBio, Vol 7, Iss 2 (2016)
mBio, 2016, 7 (2), pp.e00331-16. ⟨10.1128/mBio.00331-16⟩
mBio, Vol 7, Iss 2, p e00331-16 (2016)

Following phagocytosis, microbes are exposed to an array of antimicrobial weapons that include reactive oxygen species (ROS) and cationic fluxes. This is significant as combinations of oxidative and cationic stresses are much more potent than the cor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b3e10f3c9d17b5391e8fea3fb7db274b
https://hal-pasteur.archives-ouvertes.fr/pasteur-01517857

Oxidative Stress Responses in the Human Fungal Pathogen, Candida albicans.

Autor: da Silva Dantas, Alessandra, Day, Alison, Ikeh, Mélanie, Kos, Iaroslava, Achan, Beatrice, Quinn, Janet

Publikováno v: Biomolecules (2218-273X); 2015, Vol. 5 Issue 1, p142-165, 24p

Mechanisms Underlying the Delayed Activation of the Cap1 Transcription Factor in Candida albicans following Combinatorial Oxidative and Cationic Stress Important for Phagocytic Potency.

Autor: Kos I; Institute for Cell and Molecular Biosciences, Faculty of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom., Patterson MJ; Institute for Cell and Molecular Biosciences, Faculty of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom., Znaidi S; Institut Pasteur, Unité Biologie et Pathogénicité Fongiques, Département Mycologie, Paris, France INRA, USC2019, Paris, France., Kaloriti D; School of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom., da Silva Dantas A; Institute for Cell and Molecular Biosciences, Faculty of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom., Herrero-de-Dios CM; School of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom., d'Enfert C; Institut Pasteur, Unité Biologie et Pathogénicité Fongiques, Département Mycologie, Paris, France INRA, USC2019, Paris, France., Brown AJ; School of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom., Quinn J; Institute for Cell and Molecular Biosciences, Faculty of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom janet.quinn@ncl.ac.uk.

Publikováno v: MBio [mBio] 2016 Mar 29; Vol. 7 (2), pp. e00331. Date of Electronic Publication: 2016 Mar 29.