Thyroid hormone induces ossification and terminal maturation in a preserved OA cartilage biomimetic model.

Autor: Korthagen NM; Department Biomedical Data Sciences, Section of Molecular Epidemiology, LUMC, Einthovenweg 20, Postzone S05-P, 2333 ZC, Leiden, The Netherlands., Houtman E; Department Biomedical Data Sciences, Section of Molecular Epidemiology, LUMC, Einthovenweg 20, Postzone S05-P, 2333 ZC, Leiden, The Netherlands., Boone I; Department Biomedical Data Sciences, Section of Molecular Epidemiology, LUMC, Einthovenweg 20, Postzone S05-P, 2333 ZC, Leiden, The Netherlands., Coutinho de Almeida R; Department Biomedical Data Sciences, Section of Molecular Epidemiology, LUMC, Einthovenweg 20, Postzone S05-P, 2333 ZC, Leiden, The Netherlands., Sivasubramaniyan K; Galapagos BV, Willem Einthovenstraat 13, Oegstgeest, 2342 BH, The Netherlands., Mahdad R; Alrijne hospital, Simon Smitweg 1, Leiderdorp, 2353 GA, The Netherlands., Nelissen RGHH; Department Biomedical Data Sciences, Section of Molecular Epidemiology, LUMC, Einthovenweg 20, Postzone S05-P, 2333 ZC, Leiden, The Netherlands., Ramos YFM; Department Biomedical Data Sciences, Section of Molecular Epidemiology, LUMC, Einthovenweg 20, Postzone S05-P, 2333 ZC, Leiden, The Netherlands., Tessari MA; Galapagos BV, Willem Einthovenstraat 13, Oegstgeest, 2342 BH, The Netherlands., Meulenbelt I; Department Biomedical Data Sciences, Section of Molecular Epidemiology, LUMC, Einthovenweg 20, Postzone S05-P, 2333 ZC, Leiden, The Netherlands. i.meulenbelt@lumc.nl.

Publikováno v: Arthritis research & therapy [Arthritis Res Ther] 2024 Apr 25; Vol. 26 (1), pp. 91. Date of Electronic Publication: 2024 Apr 25.

Microencapsulated stem cells reduce cartilage damage in a material dependent manner following minimally invasive intra-articular injection in an OA rat model.

Autor: Johnbosco C; Department of Developmental BioEngineering, TechMed Centre, University of Twente, the Netherlands., Karbaat L; Department of Developmental BioEngineering, TechMed Centre, University of Twente, the Netherlands., Korthagen NM; Faculty of Veterinary Sciences Department of equine sciences, University of Utrecht, the Netherlands.; Department of Orthopaedics, University Medical Centre Utrecht, the Netherlands., Warmink K; Department of Orthopaedics, University Medical Centre Utrecht, the Netherlands., Koerselman M; Department of Developmental BioEngineering, TechMed Centre, University of Twente, the Netherlands., Coeleveld K; Department of Rheumatology & Clinical Immunology, University Medical Centre Utrecht, the Netherlands., Becker M; Department of Developmental BioEngineering, TechMed Centre, University of Twente, the Netherlands., van Loo B; Department of Developmental BioEngineering, TechMed Centre, University of Twente, the Netherlands., Zoetebier B; Department of Developmental BioEngineering, TechMed Centre, University of Twente, the Netherlands., Both S; Department of Developmental BioEngineering, TechMed Centre, University of Twente, the Netherlands., Weinans H; Department of Orthopaedics, University Medical Centre Utrecht, the Netherlands., Karperien M; Department of Developmental BioEngineering, TechMed Centre, University of Twente, the Netherlands., Leijten J; Department of Developmental BioEngineering, TechMed Centre, University of Twente, the Netherlands.

Publikováno v: Materials today. Bio [Mater Today Bio] 2023 Sep 07; Vol. 22, pp. 100791. Date of Electronic Publication: 2023 Sep 07 (Print Publication: 2023).

Mesenchymal stem/stromal cells-derived extracellular vesicles as a potentially more beneficial therapeutic strategy than MSC-based treatment in a mild metabolic osteoarthritis model.

Autor: Warmink K; Regenerative Medicine Center, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.; Department of Orthopedics, University Medical Center Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands., Rios JL; Regenerative Medicine Center, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.; Department of Orthopedics, University Medical Center Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands., Varderidou-Minasian S; Regenerative Medicine Center, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.; Center for Molecular Medicine, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands., Torres-Torrillas M; Bioregenerative Medicine and Applied Surgery Research Group, Department of Animal Medicine and Surgery, CEU Cardenal Herrera University, CEU Universities, Valencia, Spain.; García Cugat Foundation CEU-UCH Chair of Medicine and Regenerative Surgery, CEU Cardenal Herrera University, CEU Universities, Valencia, Spain., van Valkengoed DR; Regenerative Medicine Center, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.; Department of Orthopedics, University Medical Center Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands., Versteeg S; Center for Translational Immunology, University Medical Center Utrecht, Utrecht University, PO Box 85090, 3508 AB, Utrecht, The Netherlands., Eijkelkamp N; Center for Translational Immunology, University Medical Center Utrecht, Utrecht University, PO Box 85090, 3508 AB, Utrecht, The Netherlands., Weinans H; Regenerative Medicine Center, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.; Department of Orthopedics, University Medical Center Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands.; Department of Biomechanical Engineering, TU Delft, Mekelweg 2, 2628 CD, Delft, The Netherlands., Korthagen NM; Regenerative Medicine Center, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.; Department of Orthopedics, University Medical Center Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands., Lorenowicz MJ; Regenerative Medicine Center, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands. lorenowicz@bprc.nl.; Center for Molecular Medicine, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands. lorenowicz@bprc.nl.; Biomedical Primate Research Centre, Lange Kleiweg 161, 2288 GJ, Rijswijk, The Netherlands. lorenowicz@bprc.nl.

Publikováno v: Stem cell research & therapy [Stem Cell Res Ther] 2023 May 24; Vol. 14 (1), pp. 137. Date of Electronic Publication: 2023 May 24.

Treatment Effects of Intra-Articular Allogenic Mesenchymal Stem Cell Secretome in an Equine Model of Joint Inflammation.

Autor: Kearney CM; School of Veterinary Medicine, University College Dublin, Dublin, Ireland., Khatab S; Department of Orthopaedics and Sports Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands., van Buul GM; Department of Orthopaedics and Sports Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.; Beacon Hospital, Dublin, Ireland., Plomp SGM; Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands., Korthagen NM; Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands., Labberté MC; School of Veterinary Medicine, University College Dublin, Dublin, Ireland., Goodrich LR; Equine Orthopaedic Research Center, Colorado State University, Fort Collins, CO, United States., Kisiday JD; Equine Orthopaedic Research Center, Colorado State University, Fort Collins, CO, United States., Van Weeren PR; Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands., van Osch GJVM; Department of Orthopaedics and Sports Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.; Department of Otorhinolaryngology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands., Brama PAJ; School of Veterinary Medicine, University College Dublin, Dublin, Ireland.

Publikováno v: Frontiers in veterinary science [Front Vet Sci] 2022 Jun 22; Vol. 9, pp. 907616. Date of Electronic Publication: 2022 Jun 22 (Print Publication: 2022).

Folate Receptor Expression by Human Monocyte-Derived Macrophage Subtypes and Effects of Corticosteroids.

Autor: Warmink K; Department of Orthopedics, University Medical Center Utrecht, Utrecht, The Netherlands., Siebelt M; Department of Orthopedics, Erasmus Medical Center, Rotterdam, The Netherlands., Low PS; Department of Chemistry, Purdue University, West Lafayette, IN, USA., Riemers FM; Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., Wang B; Department of Chemistry, Purdue University, West Lafayette, IN, USA., Plomp SGM; Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., Tryfonidou MA; Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., van Weeren PR; Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., Weinans H; Department of Orthopedics, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Biomechanical Engineering, TU Delft, Delft, The Netherlands., Korthagen NM; Department of Orthopedics, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

Publikováno v: Cartilage [Cartilage] 2022 Jan-Mar; Vol. 13 (1), pp. 19476035221081469.