Zobrazeno 1 - 10
of 2 261
pro vyhledávání: '"Korsakov IN"'
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 13, Iss 3, Pp 219-230 (2024)
Introduction. The study of the systemic exposure of a new original drug is an essential part of its preclinical study. 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide is a new selective carbonic anhydrase II inhibitor for the treatment o
Externí odkaz:
https://doaj.org/article/52838cbd2d95414faabcc41820fa7e0e
Publikováno v:
European Journal of Mineralogy, Vol 36, Pp 797-811 (2024)
Selected crystals of natural K-bearing tourmalines, extracted from a quartzofeldspathic rock from the Kumdy-Kol microdiamond deposit (an ultrahigh-pressure region of Kokchetav Massif, northern Kazakhstan), were characterized using a scanning electron
Externí odkaz:
https://doaj.org/article/275b16695d1745a0b27dc6ca60959e7b
Autor:
Samoshkina, Yulia, Petrov, Dmitriy, Telegin, Andrei, Sukhorukov, Yurii, Kaul, Andrei, Korsakov, Igor
Magnetic circular dichroism (MCD) spectroscopy was used to study the features of the electronic structure of an epitaxial La0.7Ca0.3MnO3 film in the range of 1.2 - 4 eV. The study of the temperature behavior of the MCD spectra made it possible to est
Externí odkaz:
http://arxiv.org/abs/2306.13510
Publikováno v:
Мелиорация и гидротехника, Vol 14, Iss 3, Pp 18-30 (2024)
Purpose: to study the features of humic fertilizer impact on water consumption, yield and quality of onions under drip irrigation in the dry-steppe zone of Saratov Trans-Volga region. Materials and methods. Field studies were carried out on dark ches
Externí odkaz:
https://doaj.org/article/1ab9fa54c1e04ea1a374dfd7f66d1a65
Publikováno v:
Записки Горного института, Vol 268, Pp 503-519 (2024)
The first results of mineralogical and geochemical studies of a unique xenolith of lithospheric mantle are presented illustrating the earlier non-described mineral association of quartz, Cr-pyrope and Cr-diopside. Structural and textural features of
Externí odkaz:
https://doaj.org/article/699ead935a484d9aa4f1a939e0ceb08e
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 14, Iss 3, Pp 304-316 (2024)
INTRODUCTION. Systemic exposure studies of a selective carbonic anhydrase II inhibitor, the isoxazole derivative 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide (TFISA), require evaluating its pharmacokinetics in whole blood because the
Externí odkaz:
https://doaj.org/article/5378cde63e634d08b90e1bdf210283a2
Autor:
Alexander L. Khokhlov, Ilya I. Yaichkov, Mikhail A. Alexeev, Mikhail K. Korsakov, Anton A. Shetnev, Sergey A. Ivanovsky, Nikita N. Volkhin, Sergey S. Petukhov, Elena A. Vasilyeva
Publikováno v:
Research Results in Pharmacology, Vol 10, Iss 2, Pp 83-95 (2024)
Introduction: 3-(2-butyl-5-chloro-1H-imidazole-4-yl)-N-[4-methoxy-3-(trifluoromethyl)phenyl]-4,5-dihydro-1,2-oxazole-5-carboxamide is new antirheumatic drug. It is necessary to identify and synthesize the biotransformation products for its complete p
Externí odkaz:
https://doaj.org/article/e7d6d2c823e64610b4e5e8e9f63e46e5
Autor:
Igor N. Korsakov, Tatiana L. Karonova, Arina A. Mikhaylova, Alexander A. Loboda, Alyona T. Chernikova, Anna G. Mikheeva, Marina V. Sharypova, Alexandra O. Konradi, Evgeny V. Shlyakhto
Publikováno v:
Digital Health, Vol 10 (2024)
Background The global demographic situation has been significantly impacted by the COVID-19 pandemic. The objective of this study was to develop a model that predicts the risk of COVID-associated mortality using clinical and laboratory data collected
Externí odkaz:
https://doaj.org/article/741a3d28018a400cba456c0434a407b9
Autor:
Alexander L. Khokhlov, Ilya I. Yaichkov, Anton А. Shetnev, Sergey A. Ivanovsky, Mikhail K. Korsakov, Mikhail A. Alexeev, Olga A. Gasilina, Nikita N. Volkhin, Sergey S. Petukhov
Publikováno v:
Research Results in Pharmacology, Vol 10, Iss 1, Pp 53-66 (2024)
Introduction: The determination of biotransformation products is an essential part of the preclinical trial of original medicines. These studies have not been conducted before for the new drug 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonam
Externí odkaz:
https://doaj.org/article/ef728f4ae0304dd09e1dfd1d51e4a270
Autor:
A. L. Khokhlov, I. I. Yaichkov, M. K. Korsakov, I. N. Kagramanyan, N. N. Volkhin, S. S. Petukhov, V. E. Zaikova
Publikováno v:
Acta Biomedica Scientifica, Vol 9, Iss 1, Pp 177-191 (2024)
Background. Determining changes in the content of monoamine neurotransmitters and their metabolites in brain structures is a necessary part of studying the pharmacodynamics of antiparkinsonian drugs. A method for the joint determination of norepineph
Externí odkaz:
https://doaj.org/article/a09aee0671c34e3a8eb3a3cf56e928e8