Structural basis of lipoprotein recognition by the bacterial Lol trafficking chaperone LolA.

Autor: Kaplan E; Department of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom., Greene NP; Department of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom., Jepson AE; Department of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom., Koronakis V; Department of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Sep 06; Vol. 119 (36), pp. e2208662119. Date of Electronic Publication: 2022 Aug 29.

MYO6 is targeted by Salmonella virulence effectors to trigger PI3-Kinase signalling and pathogen invasion into host cells

Autor: Brooks, A.B.E., Humphreys, D., Singh, V., Davidson, A.C., Adren, S.D., Buss, F., Koronakis, V.

Publikováno v: Proceedings of the National Academy of Sciences

To establish infections, Salmonella injects virulence effectors that hijack the host actin cytoskeleton and phosphoinositide signaling to drive pathogen invasion. How effectors reprogram the cytoskeleton network remains unclear. By reconstituting the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::2aac43df4fd65eef9c4cb7300b0acb04

A kinase-independent function of PAK is crucial for pathogen-mediated actin remodelling.

Autor: Davidson A; Department of Pathology, University of Cambridge, Cambridge, United Kingdom., Tyler J; Department of Pathology, University of Cambridge, Cambridge, United Kingdom., Hume P; Department of Pathology, University of Cambridge, Cambridge, United Kingdom., Singh V; Department of Pathology, University of Cambridge, Cambridge, United Kingdom., Koronakis V; Department of Pathology, University of Cambridge, Cambridge, United Kingdom.

Publikováno v: PLoS pathogens [PLoS Pathog] 2021 Aug 30; Vol. 17 (8), pp. e1009902. Date of Electronic Publication: 2021 Aug 30 (Print Publication: 2021).

Immunodominant extracellular loops of Treponema pallidum FadL outer membrane proteins elicit antibodies with opsonic and growth-inhibitory activities.

Autor: Delgado, Kristina N.¹ (AUTHOR), Caimano, Melissa J.^1,2,3,4 (AUTHOR), Orbe, Isabel C.² (AUTHOR), Vicente, Crystal F.² (AUTHOR), La Vake, Carson J.² (AUTHOR), Grassmann, André A.¹ (AUTHOR), Moody, M. Anthony^5,6,7 (AUTHOR), Radolf, Justin D.^1,2,3,4,8,9 (AUTHOR), Hawley, Kelly L.^1,2,4,8,10 (AUTHOR) hawley@uchc.edu

Publikováno v: PLoS Pathogens. 12/23/2024, Vol. 20 Issue 12, p1-27. 27p.

Heterogeneous stiffness of the bone marrow microenvironment regulates the fate decision of haematopoietic stem and progenitor cells.

Autor: Shi, Guolin^1,2,3 (AUTHOR), Chang, Zhuo⁴ (AUTHOR), Zhang, Pan⁵ (AUTHOR), Zou, Xiaohang^1,2,3 (AUTHOR), Zheng, Xinmin^1,2,3 (AUTHOR), Liu, Xiru^1,2,3 (AUTHOR), Yan, Jinxiao^1,2,3 (AUTHOR), Xu, Huiyun^1,2,3 (AUTHOR), Tian, Zhenhao^1,2,3 (AUTHOR), Zhang, Nu^1,2,3 (AUTHOR), Cui, Ning^1,2,3 (AUTHOR), Sun, Leming^1,2,3 (AUTHOR), Xu, Guangkui⁴ (AUTHOR) guangkuixu@mail.xjtu.edu.cn, Yang, Hui^1,2,3 (AUTHOR) kittyyh@nwpu.edu.cn

Publikováno v: Cell Proliferation. Dec2024, Vol. 57 Issue 12, p1-19. 19p.