Toll-Like Receptor 7 Agonist RG7854 Mediates Therapeutic Efficacy and Seroconversion in Woodchucks With Chronic Hepatitis B.

Autor: Wildum S; Roche Pharma, Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Korolowicz KE; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, United States., Suresh M; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, United States., Steiner G; Roche Pharma, Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Dai L; Roche Pharma, Research and Early Development, Roche Innovation Center Shanghai, Shanghai, China., Li B; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, United States., Yon C; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, United States., De Vera Mudry MC; Roche Pharma, Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Regenass-Lechner F; Roche Pharma, Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Huang X; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, United States., Hong X; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, United States., Murreddu MG; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, United States., Kallakury BV; Department of Pathology, Georgetown University Medical Center, Washington, DC, United States., Young JAT; Roche Pharma, Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Menne S; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2022 May 23; Vol. 13, pp. 884113. Date of Electronic Publication: 2022 May 23 (Print Publication: 2022).

Combination Treatment with the Vimentin-Targeting Antibody hzVSF and Tenofovir Suppresses Woodchuck Hepatitis Virus Infection in Woodchucks.

Autor: Korolowicz KE; Department of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC 20057, USA., Suresh M; Department of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC 20057, USA., Li B; Department of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC 20057, USA., Huang X; Department of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC 20057, USA., Yon C; Department of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC 20057, USA., Kallakury BV; Department of Pathology, Georgetown University Medical Center, Washington, DC 20057, USA., Lee KP; ImmuneMed, Inc., Chuncheon BioTown, Soyanggang ro 32, Chuncheon-si 24232, Gangwon-do, Korea., Park S; ImmuneMed, Inc., Chuncheon BioTown, Soyanggang ro 32, Chuncheon-si 24232, Gangwon-do, Korea., Kim YW; ImmuneMed, Inc., Chuncheon BioTown, Soyanggang ro 32, Chuncheon-si 24232, Gangwon-do, Korea., Menne S; Department of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC 20057, USA.

Publikováno v: Cells [Cells] 2021 Sep 05; Vol. 10 (9). Date of Electronic Publication: 2021 Sep 05.

Suitability of the woodchuck HCC as a preclinical model for evaluation of intra-arterial therapies.

Autor: Kim AY; Department of Radiology Medstar Georgetown University Hospital Washington District of Columbia., Yacoub JH; Department of Radiology Medstar Georgetown University Hospital Washington District of Columbia., Field DH; Department of Radiology Medstar Georgetown University Hospital Washington District of Columbia., Park BU; Department of Pathology and Laboratory Medicine Medstar Georgetown University Hospital Washington District of Columbia., Kallakury B; Department of Pathology and Laboratory Medicine Medstar Georgetown University Hospital Washington District of Columbia., Korolowicz KE; Department of Microbiology and Immunology Georgetown University Medical Center Washington District of Columbia., Menne S; Department of Microbiology and Immunology Georgetown University Medical Center Washington District of Columbia.

Publikováno v: Animal models and experimental medicine [Animal Model Exp Med] 2020 Feb 09; Vol. 3 (1), pp. 98-102. Date of Electronic Publication: 2020 Feb 09 (Print Publication: 2020).

Antiviral Efficacy and Host Innate Immunity Associated with SB 9200 Treatment in the Woodchuck Model of Chronic Hepatitis B.

Autor: Korolowicz KE; Department of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC, 20057, United States of America., Iyer RP; Spring Bank Pharmaceuticals, Inc., Suite S-7, 113 Cedar Street, Milford, MA, 01757, United States of America., Czerwinski S; Department of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC, 20057, United States of America., Suresh M; Department of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC, 20057, United States of America., Yang J; Department of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC, 20057, United States of America., Padmanabhan S; Spring Bank Pharmaceuticals, Inc., Suite S-7, 113 Cedar Street, Milford, MA, 01757, United States of America., Sheri A; Spring Bank Pharmaceuticals, Inc., Suite S-7, 113 Cedar Street, Milford, MA, 01757, United States of America., Pandey RK; Spring Bank Pharmaceuticals, Inc., Suite S-7, 113 Cedar Street, Milford, MA, 01757, United States of America., Skell J; Spring Bank Pharmaceuticals, Inc., Suite S-7, 113 Cedar Street, Milford, MA, 01757, United States of America., Marquis JK; Spring Bank Pharmaceuticals, Inc., Suite S-7, 113 Cedar Street, Milford, MA, 01757, United States of America., Kallakury BV; Department of Pathology, Georgetown University Medical Center, Washington, DC, 20057, United States of America., Tucker RD; Department of Comparative Medicine, Georgetown University Medical Center, Washington, DC, 20057, United States of America., Menne S; Department of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC, 20057, United States of America.

Publikováno v: PloS one [PLoS One] 2016 Aug 23; Vol. 11 (8), pp. e0161313. Date of Electronic Publication: 2016 Aug 23 (Print Publication: 2016).