Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Kornelis S M Van der Geest"'
Autor:
Elisabeth Brouwer, Kornelis S M van der Geest, Maria Sandovici, Yannick van Sleen, Janneke H Terpstra, Marieke van der Heiden, Debbie van Baarle, Rosanne D Reitsema, Idil Esen, Elisabeth Raveling-Eelsing, Thomas Lieber, Annemarie M Buisman
Publikováno v:
RMD Open, Vol 8, Iss 2 (2022)
Objectives Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are overlapping autoinflammatory diseases affecting people over 50 years. The diseases are treated with immunosuppressive drugs such as prednisolone, methotrexate, leflunomide and
Externí odkaz:
https://doaj.org/article/76c7e8068fd342b7b2e4a6545ce65972
Autor:
Kornelis S M van der Geest, Wayel H Abdulahad, Gerda Horst, Pedro G Lorencetti, Johan Bijzet, Suzanne Arends, Marieke van der Heiden, Anne-Marie Buisman, Bart-Jan Kroesen, Elisabeth Brouwer, Annemieke M H Boots
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0125373 (2015)
Measuring changes of the T cell receptor (TCR) repertoire is important to many fields of medicine. Flow cytometry is a popular technique to study the TCR repertoire, as it quickly provides insight into the TCR-Vβ usage among well-defined populations
Externí odkaz:
https://doaj.org/article/646b9ff1a2564b65871e06e6686c1bc4
Autor:
Nato Teteloshvili, Joost Kluiver, Kornelis S M van der Geest, Roelof Jan van der Lei, Pytrick Jellema, Graham Pawelec, Elisabeth Brouwer, Bart-Jan Kroesen, Annemieke M H Boots, Anke van den Berg
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137556 (2015)
MicroRNAs (miRNAs) have emerged as important players in the regulation of T-cell functionality. However, comprehensive insight into the extent of age-related miRNA changes in T cells is lacking. We established miRNA expression patterns of CD45RO- na
Externí odkaz:
https://doaj.org/article/e111b250c8744ebeb085817d942ef817
Autor:
Paulina Chalan, Bart-Jan Kroesen, Kornelis S M van der Geest, Minke G Huitema, Wayel H Abdulahad, Johan Bijzet, Elisabeth Brouwer, Annemieke M H Boots
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79370 (2013)
Improved understanding of the immune events discriminating between seropositive arthralgia and clinical synovitis is of key importance in rheumatology research. Ample evidence suggests a role for Th17 cells in rheumatoid arthritis. We hypothesized th
Externí odkaz:
https://doaj.org/article/9e023a2bab484e2096a20549d3ca0911
Autor:
Rosanne D. Reitsema, Bernd-Cornèl Hesselink, Wayel H. Abdulahad, Kornelis S. M. van der Geest, Elisabeth Brouwer, Peter Heeringa, Yannick van Sleen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundGiant Cell Arteritis (GCA) and Polymyalgia Rheumatica (PMR) are overlapping inflammatory diseases. Antigen-presenting cells (APCs), including monocytes and dendritic cells (DCs), are main contributors to the immunopathology of GCA and PMR.
Externí odkaz:
https://doaj.org/article/c1fdee70017543ecbe09a34c36c96e07
Autor:
Pieter H. Nienhuis, Marieke van Nieuwland, Gijs D. van Praagh, Karolina Markusiewicz, Edgar M. Colin, Kornelis S. M. van der Geest, Nils Wagenaar, Elisabeth Brouwer, Celina Alves, Riemer H. J. A. Slart
Publikováno v:
Diagnostics, Vol 14, Iss 1, p 62 (2023)
(1) Background: In giant cell arteritis (GCA), the assessment of cranial arteries using [18F]fluorodeoxyglucose ([18F]FDG) positron emission tomography (PET) combined with low-dose computed tomography (CT) may be challenging due to low image quality.
Externí odkaz:
https://doaj.org/article/400fccbfadec47bba747423ae4c1cd76
Autor:
Kornelis S. M. van der Geest, Maria Sandovici, Pieter H. Nienhuis, Riemer H. J. A. Slart, Peter Heeringa, Elisabeth Brouwer, William F. Jiemy
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are two interrelated inflammatory diseases affecting patients above 50 years of age. Patients with GCA suffer from granulomatous inflammation of medium- to large-sized arteries. This inflamm
Externí odkaz:
https://doaj.org/article/4eb1ec8a25564c3a9dc048ca8f0b667c
Autor:
Lisa M. Duff, Andrew F. Scarsbrook, Nishant Ravikumar, Russell Frood, Gijs D. van Praagh, Sarah L. Mackie, Marc A. Bailey, Jason M. Tarkin, Justin C. Mason, Kornelis S. M. van der Geest, Riemer H. J. A. Slart, Ann W. Morgan, Charalampos Tsoumpas
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 343 (2023)
The aim of this study was to develop and validate an automated pipeline that could assist the diagnosis of active aortitis using radiomic imaging biomarkers derived from [18F]-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography (FDG P
Externí odkaz:
https://doaj.org/article/7d7a3b735b86439e87f00a13c1d8467f
Autor:
Rick Wilbrink, Anneke Spoorenberg, Suzanne Arends, Kornelis S. M. van der Geest, Elisabeth Brouwer, Hendrika Bootsma, Frans G. M. Kroese, Gwenny M. Verstappen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
B-cells have received little attention in axial spondyloarthritis (axSpA) and for this reason their role in pathogenesis remains unclear. However, there are indications that B-cells may be involved in the disease process. Our objective was to obtain
Externí odkaz:
https://doaj.org/article/45b1be5828094327b32925bfaa910762
Autor:
Rosanne D. Reitsema, Annemieke M. H. Boots, Kornelis S. M. van der Geest, Maria Sandovici, Peter Heeringa, Elisabeth Brouwer
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Vasculitis refers to inflammation of blood vessels and can cause a variety of serious complications depending on which vessels are affected. Two different forms of vasculitis are Giant Cell Arteritis (GCA) and Granulomatosis with Polyangiitis (GPA).
Externí odkaz:
https://doaj.org/article/172c0b6fc7cc46cab3f753b5b226d337