Overexpression of transposable elements is associated with immune evasion and poor outcome in colorectal cancer

Autor: Jayne A. Barbour, Kornelia Gladysz, Xiaoqiang Zhu, Hu Fang, Jason W. H. Wong

Publikováno v: European Journal of Cancer. 157:94-107

Aim High immune cell infiltration of the tumour microenvironment is generally associated with a good prognosis in solid cancers. However, a subset of patients with colorectal cancer (CRC) tumours with high immune cell infiltration have a poor outcome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426da36925d6a5e53ecdd54eeb10cc9d
https://doi.org/10.1016/j.ejca.2021.08.003

Contribution of allelic imbalance to colorectal cancer

Autor: Aurora Taira, Emmanouil T. Dermitzakis, Sandeep Kumar Botla, Jussi Taipale, Päivi Sulo, Ulrika A. Hänninen, Bernhard Schmierer, Roosa-Maria Plaketti, Kashyap Dave, Niko Välimäki, Tatiana Cajuso, Torben F. Ørntoft, Anna Vähärautio, Päivi Pihlajamaa, Mervi Aavikko, Maria Sokolova, Halit Ongen, Sari Tuupanen, Johanna Kondelin, Outi Kilpivaara, Anna Lepistö, Kornelia Gladysz, Jukka-Pekka Mecklin, Esa Pitkänen, Eevi Kaasinen, Heli Rauanheimo, Marta Grau, Lauri A. Aaltonen, Mikko P. Turunen, Ari Ristimäki, Linda van den Berg, Riku Katainen, Tuomo Hartonen, Jesper B. Bramsen, Claus L. Andersen, Teemu Kivioja, Tomas Tanskanen, Kimmo Palin, Biswajyoti Sahu, Laura Renkonen-Sinisalo

Publikováno v: Palin, K, Pitkänen, E, Turunen, M, Sahu, B, Pihlajamaa, P, Kivioja, T, Kaasinen, E, Välimäki, N, Hänninen, U A, Cajuso, T, Aavikko, M, Tuupanen, S, Kilpivaara, O, van den Berg, L, Kondelin, J, Tanskanen, T, Katainen, R, Grau, M, Rauanheimo, H, Plaketti, R-M, Taira, A, Sulo, P, Hartonen, T, Dave, K, Schmierer, B, Botla, S, Sokolova, M, Vähärautio, A, Gladysz, K, Ongen, H, Dermitzakis, E, Bramsen, J B, Ørntoft, T F, Andersen, C L, Ristimäki, A, Lepistö, A, Renkonen-Sinisalo, L, Mecklin, J-P, Taipale, J & Aaltonen, L A 2018, ' Contribution of allelic imbalance to colorectal cancer ', Nature Communications, vol. 9, 3664 . https://doi.org/10.1038/s41467-018-06132-1
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Nature Communications
Nature Communications, Vol. 9, No 1 (2018) P. 3664

Point mutations in cancer have been extensively studied but chromosomal gains and losses have been more challenging to interpret due to their unspecific nature. Here we examine high-resolution allelic imbalance (AI) landscape in 1699 colorectal cance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12af55a05ccaa6e0100715add27700fa
http://urn.fi/URN:NBN:fi:jyu-201809174145