Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kornelia Gladysz"'
Autor:
Kimmo Palin, Esa Pitkänen, Mikko Turunen, Biswajyoti Sahu, Päivi Pihlajamaa, Teemu Kivioja, Eevi Kaasinen, Niko Välimäki, Ulrika A. Hänninen, Tatiana Cajuso, Mervi Aavikko, Sari Tuupanen, Outi Kilpivaara, Linda van den Berg, Johanna Kondelin, Tomas Tanskanen, Riku Katainen, Marta Grau, Heli Rauanheimo, Roosa-Maria Plaketti, Aurora Taira, Päivi Sulo, Tuomo Hartonen, Kashyap Dave, Bernhard Schmierer, Sandeep Botla, Maria Sokolova, Anna Vähärautio, Kornelia Gladysz, Halit Ongen, Emmanouil Dermitzakis, Jesper Bertram Bramsen, Torben Falck Ørntoft, Claus Lindbjerg Andersen, Ari Ristimäki, Anna Lepistö, Laura Renkonen-Sinisalo, Jukka-Pekka Mecklin, Jussi Taipale, Lauri A. Aaltonen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
In this study the authors examine the allelic imbalance (AI) landscape of colorectal cancer, reporting loss of TP53 as a driver of AI. They use CRISPR-Cas9 screens to identify 79 genes (within AI regions) regulating cell growth and identify a network
Externí odkaz:
https://doaj.org/article/0d1e862be9834942b8b1513c12b2e466
Publikováno v:
European Journal of Cancer. 157:94-107
Aim High immune cell infiltration of the tumour microenvironment is generally associated with a good prognosis in solid cancers. However, a subset of patients with colorectal cancer (CRC) tumours with high immune cell infiltration have a poor outcome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426da36925d6a5e53ecdd54eeb10cc9d
https://doi.org/10.1016/j.ejca.2021.08.003
https://doi.org/10.1016/j.ejca.2021.08.003
ObjectiveThe immune system plays a key role in protecting against cancer. Increased immune infiltration in tumor tissue is usually associated with improved clinical outcome, but in colorectal cancer (CRC), excessive immune infiltration has also been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2044caaec27d1c4c0e89aca969f668c
https://doi.org/10.1101/2020.07.14.20129031
https://doi.org/10.1101/2020.07.14.20129031
Autor:
Aurora Taira, Emmanouil T. Dermitzakis, Sandeep Kumar Botla, Jussi Taipale, Päivi Sulo, Ulrika A. Hänninen, Bernhard Schmierer, Roosa-Maria Plaketti, Kashyap Dave, Niko Välimäki, Tatiana Cajuso, Torben F. Ørntoft, Anna Vähärautio, Päivi Pihlajamaa, Mervi Aavikko, Maria Sokolova, Halit Ongen, Sari Tuupanen, Johanna Kondelin, Outi Kilpivaara, Anna Lepistö, Kornelia Gladysz, Jukka-Pekka Mecklin, Esa Pitkänen, Eevi Kaasinen, Heli Rauanheimo, Marta Grau, Lauri A. Aaltonen, Mikko P. Turunen, Ari Ristimäki, Linda van den Berg, Riku Katainen, Tuomo Hartonen, Jesper B. Bramsen, Claus L. Andersen, Teemu Kivioja, Tomas Tanskanen, Kimmo Palin, Biswajyoti Sahu, Laura Renkonen-Sinisalo
Publikováno v:
Palin, K, Pitkänen, E, Turunen, M, Sahu, B, Pihlajamaa, P, Kivioja, T, Kaasinen, E, Välimäki, N, Hänninen, U A, Cajuso, T, Aavikko, M, Tuupanen, S, Kilpivaara, O, van den Berg, L, Kondelin, J, Tanskanen, T, Katainen, R, Grau, M, Rauanheimo, H, Plaketti, R-M, Taira, A, Sulo, P, Hartonen, T, Dave, K, Schmierer, B, Botla, S, Sokolova, M, Vähärautio, A, Gladysz, K, Ongen, H, Dermitzakis, E, Bramsen, J B, Ørntoft, T F, Andersen, C L, Ristimäki, A, Lepistö, A, Renkonen-Sinisalo, L, Mecklin, J-P, Taipale, J & Aaltonen, L A 2018, ' Contribution of allelic imbalance to colorectal cancer ', Nature Communications, vol. 9, 3664 . https://doi.org/10.1038/s41467-018-06132-1
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Nature Communications
Nature Communications, Vol. 9, No 1 (2018) P. 3664
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Nature Communications
Nature Communications, Vol. 9, No 1 (2018) P. 3664
Point mutations in cancer have been extensively studied but chromosomal gains and losses have been more challenging to interpret due to their unspecific nature. Here we examine high-resolution allelic imbalance (AI) landscape in 1699 colorectal cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12af55a05ccaa6e0100715add27700fa
http://urn.fi/URN:NBN:fi:jyu-201809174145
http://urn.fi/URN:NBN:fi:jyu-201809174145
Autor:
Xiucong Bao, Kornelia Gladysz, Ying Xiong, Yi Man Eva Fung, Jason W. H. Wong, Wei Zhang, Zheng Liu, Gaofei Tian, Karen Wing Yee Yuen, Xiang David Li
Publikováno v:
Molecular Cell. 76:660-675.e9
Histone posttranslational modifications (PTMs) regulate chromatin structure and dynamics during various DNA-associated processes. Here, we report that lysine glutarylation (Kglu) occurs at 27 lysine residues on human core histones. Using semi-synthet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95184b446dd7a273a8010dc94485b0d8
https://doi.org/10.1016/j.molcel.2019.08.018
https://doi.org/10.1016/j.molcel.2019.08.018
Autor:
Palin, Kimmo, Pitkänen, Esa, Turunen, Mikko, Sahu, Biswajyoti, Pihlajamaa, Päivi, Kivioja, Teemu, Kaasinen, Eevi, Välimäki, Niko, Hänninen, Ulrika A., Cajuso, Tatiana, Aavikko, Mervi, Tuupanen, Sari, Kilpivaara, Outi, van den Berg, Linda, Kondelin, Johanna, Tanskanen, Tomas, Katainen, Riku, Grau, Marta, Rauanheimo, Heli, Plaketti, Roosa-Maria
Publikováno v:
Nature Communications; 9/10/2018, Vol. 9 Issue 1, p1-1, 1p