Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kornelia Fritsch"'
Autor:
Antonella Catalano, Mojca Adlesic, Thorsten Kaltenbacher, Rhena F. U. Klar, Joachim Albers, Philipp Seidel, Laura P. Brandt, Tomas Hejhal, Philipp Busenhart, Niklas Röhner, Kyra Zodel, Kornelia Fritsch, Peter J. Wild, Justus Duyster, Ralph Fritsch, Tilman Brummer, Ian J. Frew
Publikováno v:
Cancers, Vol 13, Iss 8, p 1852 (2021)
Oncogenic mutations in RAS family genes arise frequently in metastatic human cancers. Here we developed new mouse and cellular models of oncogenic HrasG12V-driven undifferentiated pleomorphic sarcoma metastasis and of KrasG12D-driven pancreatic ducta
Externí odkaz:
https://doaj.org/article/847afd0f532a45c886ce0c5af605fd82
Autor:
Justus Duyster, Friederike Nollmann, Rhena F. U. Klar, Saskia Hussung, Uwe A. Wittel, Ralph Fritsch, Melanie Boerries, Julian Hipp, Kornelia Fritsch, Sandra Michalczyk, Florian Scherer, Marie Follo, Nikolas von Bubnoff
Publikováno v:
The Journal of Molecular Diagnostics. 22:943-956
Detection and quantification of tumor-derived KRAS and NRAS mutations in plasma cell-free DNA (cfDNA) holds great potential for cancer diagnostics and treatment response monitoring. Because of high sensitivity, specificity, robustness, and affordabil
Autor:
Madhu S. Kumar, Julian Downward, Gordon Stamp, Roger George, Kornelia Fritsch, Beth Reason, Inge de Krijger, Ralph Fritsch, Markus E. Diefenbacher
Publikováno v:
Cell
Summary RAS proteins are important direct activators of p110α, p110γ, and p110δ type I phosphoinositide 3-kinases (PI3Ks), interacting via an amino-terminal RAS-binding domain (RBD). Here, we investigate the regulation of the ubiquitous p110β iso
Autor:
William R. Otto, Nicholas A. Wright, Yassar A. Qureshi, Kornelia Fritsch, Naomi Guppy, Hemant M. Kocher, Malcolm R. Alison, Mona E. El-Bahrawy, Richard Poulsom, Rosemary Jeffery
Publikováno v:
Pancreas. 41(6)
Trefoil factor family (TFF) peptides promote wound healing in the gut. Recent evidence has suggested that TFF3 may be a pancreatic mitogen, an unusual role for TFF peptides. We sought to clarify human pancreatic TFF and mucin expression and performed