Cut from the same cloth: RNAs transcribed from regulatory elements.

Autor: Stasevich EM; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Simonova AV; Laboratory of Intracellular Signaling in Health and Disease, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Bogomolova EA; Laboratory of Intracellular Signaling in Health and Disease, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia; Moscow Center for Advanced Studies, Moscow, Russia., Murashko MM; Laboratory of Intracellular Signaling in Health and Disease, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia; Moscow Center for Advanced Studies, Moscow, Russia., Uvarova AN; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Zheremyan EA; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Korneev KV; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Schwartz AM; Department of Human Biology, University of Haifa, Haifa, Israel., Kuprash DV; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Demin DE; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia. Electronic address: denis.demin@phystech.edu.

Publikováno v: Biochimica et biophysica acta. Gene regulatory mechanisms [Biochim Biophys Acta Gene Regul Mech] 2024 Sep; Vol. 1867 (3), pp. 195049. Date of Electronic Publication: 2024 Jul 02.

[The rs2564978(T) Allele Associated with Severe Influenza A Disrupts the Binding Site for Myeloid Differentiation Factor PU.1 and Reduces CD55/DAF Gene Promoter Activity in Macrophages].

Autor: Uvarova AN; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.; uvarowww@gmail.com., Tkachenko EA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.; Biological Faculty, Moscow State University, Moscow, 119234 Russia., Stasevich EM; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia., Bogomolova EA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.; Department of Molecular and Biological Physics, Moscow Institute of Physics and Technology, Moscow, 141701 Russia., Zheremyan EA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.; Biological Faculty, Moscow State University, Moscow, 119234 Russia., Kuprash DV; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.; Biological Faculty, Moscow State University, Moscow, 119234 Russia.; Department of Molecular and Biological Physics, Moscow Institute of Physics and Technology, Moscow, 141701 Russia., Korneev KV; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.; National Research Center for Hematology, Ministry of Health of the Russian Federation, Moscow, 125167 Russia.

Publikováno v: Molekuliarnaia biologiia [Mol Biol (Mosk)] 2024 Mar-Apr; Vol. 58 (2), pp. 270-281.

rs71327024 Associated with COVID-19 Hospitalization Reduces CXCR6 Promoter Activity in Human CD4 ⁺ T Cells via Disruption of c-Myb Binding.

Autor: Uvarova AN; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia., Stasevich EM; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Ustiugova AS; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Mitkin NA; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Zheremyan EA; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia., Sheetikov SA; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.; National Research Center for Hematology, 125167 Moscow, Russia., Zornikova KV; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.; National Research Center for Hematology, 125167 Moscow, Russia., Bogolyubova AV; National Research Center for Hematology, 125167 Moscow, Russia., Rubtsov MA; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia., Kulakovskiy IV; Institute of Protein Research, 142290 Pushchino, Russia., Kuprash DV; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia., Korneev KV; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; National Research Center for Hematology, 125167 Moscow, Russia., Schwartz AM; Department of Human Biology, Faculty of Natural Sciences, University of Haifa, 199 Abba Khoushy Avenue, Mount Carmel, Haifa 3498838, Israel.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Sep 07; Vol. 24 (18). Date of Electronic Publication: 2023 Sep 07.

Adversary of DNA integrity: A long non-coding RNA stimulates driver oncogenic chromosomal rearrangement in human thyroid cells.

Autor: Demin DE; Laboratory for the Transmission of Intracellular Signals in Normal and Pathological Conditions, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Murashko MM; Laboratory for the Transmission of Intracellular Signals in Normal and Pathological Conditions, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.; Department of Biological and Medical Physics, Moscow Institute of Physics and Technology, Moscow, Russia., Uvarova AN; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.; Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia., Stasevich EM; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Shyrokova EY; Department of Biological and Medical Physics, Moscow Institute of Physics and Technology, Moscow, Russia.; Department of Cancer Cell Biology, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Gorlachev GE; GBUZ Moscow Clinical Scientific Center named after Loginov MHD., Zaretsky AR; Department of Molecular Technologies, Research Institute of Translational Medicine, N. I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation., Korneev KV; Laboratory for the Transmission of Intracellular Signals in Normal and Pathological Conditions, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.; National Research Center for Hematology, Moscow, Russia., Ustiugova AS; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Tkachenko EA; Laboratory for the Transmission of Intracellular Signals in Normal and Pathological Conditions, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.; Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia., Kostenko VV; Laboratory for the Transmission of Intracellular Signals in Normal and Pathological Conditions, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.; Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia., Tatosyan KA; Laboratory of Eukaryotic Genome Evolution, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Sheetikov SA; Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia.; National Research Center for Hematology, Moscow, Russia., Spirin PV; Department of Cancer Cell Biology, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Kuprash DV; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.; Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia., Schwartz AM; Department of Biological and Medical Physics, Moscow Institute of Physics and Technology, Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.

Publikováno v: International journal of cancer [Int J Cancer] 2023 Apr 01; Vol. 152 (7), pp. 1452-1462. Date of Electronic Publication: 2023 Jan 16.

[The Minor T Allele of the Single Nucleotide Polymorphism rs 13360222 Decreases the Activity of the HAVCR2 Gene Enhancer in a Cell Model of Human Macrophages].

Autor: Uvarova AN; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.; Faculty of Biology, Moscow State University, Moscow, 119234 Russia., Ustiugova AS; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia., Mitkin NA; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia., Schwartz AM; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia., Korneev KV; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia., Kuprash DV; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.; Faculty of Biology, Moscow State University, Moscow, 119234 Russia.; kuprash@gmail.com.

Publikováno v: Molekuliarnaia biologiia [Mol Biol (Mosk)] 2022 Jan-Feb; Vol. 56 (1), pp. 126-134.