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pro vyhledávání: '"Korlin-Downs A"'
Autor:
Sunyuan Zhang, Nicholas A. Williamson, Lisa Duvick, Alexander Lee, Harry T. Orr, Austin Korlin-Downs, Praseuth Yang, Yee-Foong Mok, David A. Jans, Marie A. Bogoyevitch
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Patients with spinocerebellar ataxia type 1 express ataxin-1 with an extended polyglutamine (polyQ) tract that forms distinctive nuclear bodies. Here, the authors characterize the cellular pathways affected by polyQ-ataxin-1, showing that it disrupts
Externí odkaz:
https://doaj.org/article/b2b32690cddc4b05a5d62aa6d6b893b2
Autor:
Marie A. Bogoyevitch, Yee-Foong Mok, Praseuth Yang, Lisa A. Duvick, Nicholas A. Williamson, Alexander Lee, David A. Jans, Harry T. Orr, Austin Korlin-Downs, Sunyuan Zhang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications
Nature Communications
The expanded polyglutamine (polyQ) tract form of ataxin-1 drives disease progression in spinocerebellar ataxia type 1 (SCA1). Although known to form distinctive intranuclear bodies, the cellular pathways and processes that polyQ-ataxin-1 influences r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1898654cb22caa3990f67ba066f7ec
https://doaj.org/article/b2b32690cddc4b05a5d62aa6d6b893b2
https://doaj.org/article/b2b32690cddc4b05a5d62aa6d6b893b2
Akademický článek
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