Výsledky vyhledávání - "Koren A. Holland"

A high observed substitution rate in the human mitochondrial DNA control region

Autor: Rosemary Alliston-Greiner, David S. Muniec, Koren A. Holland, Nicola Woodyatt, Peter Gill, Victor W. Weedn, Mitchell M. Holland, Thomas J. Parsons, Kevin Sullivan, Dianna L. Berry, Mark R. Wilson

Publikováno v: Nature Genetics. 15:363-368

The rate and pattern of sequence substitutions in the mitochondrial DNA (mtDNA) control region (CR) is of central importance to studies of human evolution and to forensic identity testing. Here, we report a direct measurement of the intergenerational

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b35a188409e774403a2a299a10293ff6
https://doi.org/10.1038/ng0497-363

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Isolation and Characterization of the Versicolorin B Synthase Gene from Aspergillus parasiticus

Autor: Jeffrey Cruz Silva, Clifford E. Barry, Robert E. Minto, Craig A. Townsend, Koren A. Holland

Publikováno v: Journal of Biological Chemistry. 271:13600-13608

Versicolorin B synthase catalyzes the side chain cyclization of racemic versiconal hemiacetal (7) to the bisfuran ring system of (−)-versicolorin B (8), an essential transformation in the aflatoxin biosynthetic pathway of Aspergillus parasiticus. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::acccb159202fe531821cab1048796080
https://doi.org/10.1074/jbc.271.23.13600

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Comparison of the complete mtDNA genome sequences of human cell lines--HL-60 and GM10742A--from individuals with pro-myelocytic leukemia and leber hereditary optic neuropathy, respectively, and the inclusion of HL-60 in the NIST human mitochondrial DNA standard reference material--SRM 2392-I

Autor: Barbara C. Levin, Thomas J. Parsons, Diane K. Hancock, Laura J. Kienker, Michael D. Coble, Diana W. Williams, Mary Pat Jones, Koren A. Holland, Kristy L. Richie

Publikováno v: Mitochondrion. 2(6)

Forensic and clinical laboratories benefit from DNA standard reference materials (SRMs) that provide the quality control and assurance that their results from sequencing unknown samples are correct. Therefore, the mitochondrial DNA (mtDNA) genome of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634f51570a9c08ace35bfaf753a511bf
https://pubmed.ncbi.nlm.nih.gov/16120335

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