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Akademický článek

Regulation of epitope exposure in the gp41 membrane-proximal external region through interactions at the apex of HIV-1 Env.

Autor: Hannah M Schapiro, Mukta D Khasnis, Koree Ahn, Alexandra Karagiaridi, Stephanie Hayden, Maria E Cilento, Michael J Root

Publikováno v: PLoS Pathogens, Vol 18, Iss 5, p e1010531 (2022)

Glycoprotein Env of human immunodeficiency virus type 1 (HIV-1) mediates viral entry through membrane fusion. Composed of gp120 and gp41 subunits arranged as a trimer-of-heterodimers, Env adopts a metastable, highly dynamic conformation on the virion

Externí odkaz: https://doaj.org/article/b8a888b33e074c6baff1d6349fdf2cb1

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Akademický článek

APC mutations in human colon lead to decreased neuroendocrine maturation of ALDH+ stem cells that alters GLP-2 and SST feedback signaling: Clue to a link between WNT and retinoic acid signalling in colon cancer development.

Autor: Tao Zhang, Koree Ahn, Brooks Emerick, Shirin R Modarai, Lynn M Opdenaker, Juan Palazzo, Gilberto Schleiniger, Jeremy Z Fields, Bruce M Boman

Publikováno v: PLoS ONE, Vol 15, Iss 10, p e0239601 (2020)

APC mutations drive human colorectal cancer (CRC) development. A major contributing factor is colonic stem cell (SC) overpopulation. But, the mechanism has not been fully identified. A possible mechanism is the dysregulation of neuroendocrine cell (N

Externí odkaz: https://doaj.org/article/38296ba3ee424c2ea578e4829e5794f1

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Regulation of epitope exposure in the gp41 membrane-proximal external region through interactions at the apex of HIV-1 Env

Autor: Hannah M. Schapiro, Mukta D. Khasnis, Koree Ahn, Alexandra Karagiaridi, Stephanie Hayden, Maria E. Cilento, Michael J. Root

Publikováno v: PLoS pathogens. 18(5)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f12230437bdb93ec8b52cebdadf0f9
https://pubmed.ncbi.nlm.nih.gov/35584191

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Autor: Brooks Emerick, Shirin R. Modarai, Bruce M. Boman, Jeremy Z. Fields, Juan P. Palazzo, Koree Ahn, Gilberto Schleiniger, Tao Zhang, Lynn M. Opdenaker

Publikováno v: PLoS ONE
PLoS ONE, Vol 15, Iss 10, p e0239601 (2020)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b8a9149599f3879b6fab3021e90dbd
http://europepmc.org/articles/PMC7592776

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A Promising Novel Target in Pancreatic Cancer: HuR Modulates Multiple Core Signaling Pathways Required for Pancreatic Tumorigenesis

Autor: David W. Rittenhouse, Myriam Gorospe, Koree Ahn, Agnes Witkiewicz, Nathan G. Richards, Vanessa A. Talbott, Charles J. Yeo, Jonathan R. Brody, Eugene P. Kennedy

Publikováno v: Gastroenterology. 140:S-1026

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb8436dd633440fa962e31199feef0b6
https://doi.org/10.1016/s0016-5085(11)64265-0

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Abstract 4256: Neuroendocrine, stem, and stromal cell interactions involved in the organization of the normal colonic stem cell niche which become disorganized during colon tumorigenesis

Autor: Lynn Opdenaker, Senem Kurtoglu, Bruce M. Boman, Koree Ahn, Tao Zhang, Shirin Modarai

Publikováno v: Cancer Research. 70:4256-4256

In development of colorectal cancer (CRC), stem cell (SC) overpopulation underlies tumor initiation and progression, but it is incompletely understood which dysregulated mechanisms cause SC overpopulation. Because neuroendocrine cell (NEC) and SC pop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::954b167a34f7c91f038b00faabc573d6
https://doi.org/10.1158/1538-7445.am10-4256

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