Does SIRT-1 Mediate Calorie Restriction and Prolong Life? – A Mini Review

Autor: Kordala Anna, Pietrzak Bogusława

Publikováno v: Polish Journal of Food and Nutrition Sciences, Vol 64, Iss 3, Pp 159-164 (2014)

Calorie restriction is the only intervention proved to prolong both average and maximum lifespan in yeast, worms, fish, rodents and possibly primates. Not only does the regimen prolong life, but it also reduces the incident of numerous age-related di

Externí odkaz: https://doaj.org/article/50fa81b39eed4b18883a7c4e03078fbf

Exercise, disease state and sex influence the beneficial effects of Fn14-depletion on survival and muscle pathology in the SOD1^G93A amyotrophic lateral sclerosis (ALS) mouse model.

Autor: Hazell, Gareth, McCallion, Eve, Ahlskog, Nina, Sutton, Emma R., Okoh, Magnus, Shaqoura, Emad I. H., Hoolachan, Joseph M., Scaife, Taylor, Iqbal, Sara, Bhomra, Amarjit, Kordala, Anna J., Scamps, Frederique, Raoul, Cedric, Wood, Matthew J. A., Bowerman, Melissa

Publikováno v: Skeletal Muscle; 10/14/2024, Vol. 14 Issue 1, p1-24, 24p

PRMT inhibitor promotes SMN2 exon 7 inclusion and synergizes with nusinersen to rescue SMA mice.

Autor: Kordala, Anna J, Stoodley, Jessica, Ahlskog, Nina, Hanifi, Muhammad, Garcia Guerra, Antonio, Bhomra, Amarjit, Lim, Wooi Fang, Murray, Lyndsay M, Talbot, Kevin, Hammond, Suzan M, Wood, Matthew JA, Rinaldi, Carlo

Publikováno v: EMBO Molecular Medicine; 11/8/2023, Vol. 15 Issue 11, p1-16, 16p

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Exercise, disease state and sex influence the beneficial effects of Fn14-depletion on survival and muscle pathology in the SOD1 ^G93A amyotrophic lateral sclerosis (ALS) mouse model.

Autor: Hazell G; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., McCallion E; School of Medicine, Keele University, Staffordshire, UK., Ahlskog N; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.; Department of Paediatrics, University of Oxford, Oxford, UK., Sutton ER; School of Medicine, Keele University, Staffordshire, UK., Okoh M; School of Medicine, Keele University, Staffordshire, UK., Shaqoura EIH; School of Medicine, Keele University, Staffordshire, UK., Hoolachan JM; School of Medicine, Keele University, Staffordshire, UK., Scaife T; School of Life Sciences, Keele University, Staffordshire, UK., Iqbal S; School of Life Sciences, Keele University, Staffordshire, UK., Bhomra A; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.; Department of Paediatrics, University of Oxford, Oxford, UK., Kordala AJ; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.; Department of Paediatrics, University of Oxford, Oxford, UK., Scamps F; INM, Univ Montpellier, INSERM, Montpellier, France., Raoul C; INM, Univ Montpellier, INSERM, Montpellier, France.; ALS Reference Center, Univ Montpellier, CHU Montpellier, Montpellier, France., Wood MJA; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.; Department of Paediatrics, University of Oxford, Oxford, UK., Bowerman M; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK. m.bowerman@keele.ac.uk.; School of Medicine, Keele University, Staffordshire, UK. m.bowerman@keele.ac.uk.; Wolfson Centre for Inherited Neuromuscular Disease, RJAH Orthopaedic Hospital, Oswestry, UK. m.bowerman@keele.ac.uk.

Publikováno v: Skeletal muscle [Skelet Muscle] 2024 Oct 14; Vol. 14 (1), pp. 23. Date of Electronic Publication: 2024 Oct 14.