Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Korbinian N. Kropp"'
Autor:
Korbinian N. Kropp, Martina Fatho, Enes Huduti, Marilena Faust, Silke Lübcke, Volker Lennerz, Annette Paschen, Matthias Theobald, Thomas Wölfel, Catherine Wölfel
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntorductionChondroitin sulfate proteoglycan 4 (CSPG4), also known as high molecular weight-melanoma associated antigen, is expressed in melanoma but also other tumor entities and constitutes an attractive target for immunotherapeutic approaches. Whi
Externí odkaz:
https://doaj.org/article/876d109a9f104f8e9183472e9034a50a
Autor:
Susanne M. Rittig, Martina S. Lutz, Kim L. Clar, Yanjun Zhou, Korbinian N. Kropp, André Koch, Andreas D. Hartkopf, Martina Hinterleitner, Lars Zender, Helmut R. Salih, Stefanie Maurer, Clemens Hinterleitner
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
In conventional T cells, OX40 has been identified as a major costimulating receptor augmenting survival and clonal expansion of effector and memory T cell populations. In regulatory T cells, (Treg) OX40 signaling suppresses cellular activity and diff
Externí odkaz:
https://doaj.org/article/5e3be70851314d40a577ae226ae4ff65
Autor:
Clemens Hinterleitner, Yanjun Zhou, Claudia Tandler, Jonas S. Heitmann, Korbinian N. Kropp, Martina Hinterleitner, André Koch, Andreas D. Hartkopf, Lars Zender, Helmut R. Salih, Stefanie Maurer
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Although treatment options in breast cancer have been improved significantly, predictive biomarkers for disease progression and metastasis are still lacking. Recent studies indicate that several TNF Receptor Superfamily members are involved in breast
Externí odkaz:
https://doaj.org/article/f1e066b6d9144fb291563d5bed57ea7b
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Platelets have a crucial function in maintaining hemostasis. However, beyond their role in coagulation and thrombus formation, platelets have been implicated to affect various pathophysiological conditions such as infectious diseases, autoimmune diso
Externí odkaz:
https://doaj.org/article/b4084cf43a93468aa174a5e020de6335
Autor:
Korbinian N. Kropp, Tim J. Schäufele, Martina Fatho, Michael Volkmar, Roland Conradi, Matthias Theobald, Thomas Wölfel, Catherine Wölfel, Chen Ling
Publikováno v:
PLoS ONE, Vol 15, Iss 9 (2020)
To facilitate preclinical testing of T-cell receptors (TCRs) derived from tumor-reactive T-cell clones it is necessary to develop convenient and rapid cloning strategies for the generation of TCR expression constructs. Herein, we describe a pDONR™2
Externí odkaz:
https://doaj.org/article/bf1526f718534fdfb86ea21355e71967
Autor:
Yanjun Zhou, Jonas S. Heitmann, Korbinian N. Kropp, Martina Hinterleitner, André Koch, Andreas D. Hartkopf, Helmut R. Salih, Clemens Hinterleitner, Stefanie Maurer
Publikováno v:
Diagnostics, Vol 11, Iss 7, p 1188 (2021)
Tumor progression and metastasis are critically dependent on the tumor microenvironment. A disintegrin and metalloproteinase 17 (ADAM17) is associated with shedding of several substrates involved in tumor progression and known to be expressed by plat
Externí odkaz:
https://doaj.org/article/47038387bcf647c7bf9acd18dd9c7c74
Publikováno v:
Cancer cell. 40(12)
Combining immune receptor engineering with conditional expression of accessory molecules holds great promise for advancing the field of cell-based immunotherapies. In this issue of Cancer Cell, Smole et al. introduce a modular single vector system to
Autor:
Sarah Schnitte, Moritz Schmidt, Susanne M. Rittig, Stefanie Maurer, Vanessa Altdörfer, Alexander Rolf Fuchs, Daniela Dörfel, Martin Müller, Helmut R. Salih, Korbinian N. Kropp, Frank Grünebach
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 7, Pp 653-664 (2019)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
The ubiquitin-proteasome system is elementary for cellular protein degradation and gained rising attention as a new target for cancer therapy due to promising clinical trials with bortezomib, the first-in class proteasome inhibitor meanwhile approved
Autor:
André Koch, Stefanie Maurer, Martina Hinterleitner, Kim L. Clar, Clemens Hinterleitner, Andreas D. Hartkopf, Jonas S. Heitmann, Yanjun Zhou, Helmut R. Salih, T Engler, Lars Zender, Korbinian N. Kropp
Publikováno v:
Cancer Immunology, Immunotherapy
Owing to their key role in several diseases including cancer, activating and inhibitory immune checkpoint molecules are increasingly exploited as targets for immunotherapy. Recently, we demonstrated that platelets, which largely influence tumor progr
Autor:
Matthias Theobald, Korbinian N. Kropp, Thomas Wölfel, Michael Volkmar, Martina Fatho, Catherine Wölfel, Roland Conradi, Tim J. Schäufele
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0238875 (2020)
PLoS ONE
PLoS ONE
To facilitate preclinical testing of T-cell receptors (TCRs) derived from tumor-reactive T-cell clones it is necessary to develop convenient and rapid cloning strategies for the generation of TCR expression constructs. Herein, we describe a pDONR™2