Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Koray Ozduman"'
Autor:
Mark W. Youngblood, Zeynep Erson-Omay, Chang Li, Hinda Najem, Süleyman Coșkun, Evgeniya Tyrtova, Julio D. Montejo, Danielle F. Miyagishima, Tanyeri Barak, Sayoko Nishimura, Akdes Serin Harmancı, Victoria E. Clark, Daniel Duran, Anita Huttner, Timuçin Avşar, Yasar Bayri, Johannes Schramm, Julien Boetto, Matthieu Peyre, Maximilien Riche, Roland Goldbrunner, Nduka Amankulor, Angeliki Louvi, Kaya Bilgüvar, M. Necmettin Pamir, Koray Özduman, Türker Kilic, James R. Knight, Matthias Simon, Craig Horbinski, Michel Kalamarides, Marco Timmer, Amy B. Heimberger, Ketu Mishra-Gorur, Jennifer Moliterno, Katsuhito Yasuno, Murat Günel
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Hedgehog signaling mediates embryologic development of the central nervous system and other tissues and is frequently hijacked by neoplasia to facilitate uncontrolled cellular proliferation. Meningiomas, the most common primary brain tumor,
Externí odkaz:
https://doaj.org/article/32c53254d0434114aadc0376769d30b2
Autor:
Esra Sümer, Ece Tek, O. Artunç Türe, Meriç Şengöz, Alp Dinçer, Alpay Özcan, M. Necmettin Pamir, Koray Özduman, Esin Ozturk-Isik
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The primary aim of Gamma Knife (GK) radiosurgery is to deliver high-dose radiation precisely to a target while conforming to the target shape. In this study, the effects of tumor shape irregularity (TSI) on GK dose-plan quality and treatment
Externí odkaz:
https://doaj.org/article/6b4957c302064f7bb0f667ceeb7a095a
Autor:
Banu Sacli-Bilmez, Ayça Erşen Danyeli, M. Cengiz Yakicier, Fuat Kaan Aras, M. Necmettin Pamir, Koray Özduman, Alp Dinçer, Esin Ozturk-Isik
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
BackgroundThe 2021 World Health Organization (WHO) Central Nervous System (CNS) Tumor Classification has suggested that isocitrate dehydrogenase wildtype (IDH-wt) WHO grade-2/3 astrocytomas with molecular features of glioblastoma should be designated
Externí odkaz:
https://doaj.org/article/f875b1e86c104120b060545f44856916
Autor:
Ahmet Harun Yaşar, Baran Bozkurt, Ayça Ersen Danyeli, Assistant Murat Imre Usseli, Mustafa Güdük, Koray Özduman, M. Necmettin Pamir
Publikováno v:
Brain and Spine, Vol 3, Iss , Pp 102155- (2023)
Externí odkaz:
https://doaj.org/article/6be372fe65f44338819dd46493678b24
Autor:
İbrahim Önder Yeniçeri, Mehmet Erdem Yıldız, Koray Özduman, Ayça Erşen Danyeli, M. Necmettin Pamir, Alp Dinçer
Publikováno v:
Diagnostic and Interventional Radiology, Vol 27, Iss 6, Pp 796-801 (2021)
PURPOSE:The reliability and reproducibility of T2-weighted imaging/ fluid-attenuated inversion recovery (T2/FLAIR) mismatch were investigated in the diagnosis of isocitrate dehydrogenase (IDH) mutant astrocytoma between WHO grade II and III diffuse h
Externí odkaz:
https://doaj.org/article/f2149ec28345448ba18e8801d73d9616
Autor:
Ege Ülgen, Özge Can, Kaya Bilguvar, Cemaliye Akyerli Boylu, Şirin Kılıçturgay Yüksel, Ayça Erşen Danyeli, O. Uğur Sezerman, M. Cengiz Yakıcıer, M. Necmettin Pamir, Koray Özduman
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-14 (2021)
Abstract Background In the clinical setting, workflows for analyzing individual genomics data should be both comprehensive and convenient for clinical interpretation. In an effort for comprehensiveness and practicality, we attempted to create a clini
Externí odkaz:
https://doaj.org/article/8d68f504ee3442278efa6a1282e8f27e
Autor:
Ege Ülgen, Sıla Karacan, Umut Gerlevik, Özge Can, Kaya Bilguvar, Yavuz Oktay, Cemaliye B. Akyerli, Şirin K. Yüksel, Ayça E. Danyeli, Tarık Tihan, O. Uğur Sezerman, M. Cengiz Yakıcıer, M. Necmettin Pamir, Koray Özduman
Publikováno v:
Biomedicines, Vol 8, Iss 12, p 574 (2020)
Little is known about the mutational processes that shape the genetic landscape of gliomas. Numerous mutational processes leave marks on the genome in the form of mutations, copy number alterations, rearrangements or their combinations. To explore gl
Externí odkaz:
https://doaj.org/article/7243f9e585904f9493bea5e128696565
Autor:
Ege Ülgen, Umut Gerlevik, Sıla Gerlevik, Yavuz Oktay, Osman Uğur Sezerman, Şevin Turcan, Koray Ozduman
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-11 (2024)
Abstract MYC dysregulation is pivotal in the onset and progression of IDH-mutant gliomas, mostly driven by copy-number alterations, regulatory element alterations, or epigenetic changes. Our pilot analysis uncovered instances of relative MYC overexpr
Externí odkaz:
https://doaj.org/article/15cc31a1daa84ffaa6fca6f853a98817
Susceptibility-Weighted MRI for Predicting NF-2 Mutations and S100 Protein Expression in Meningiomas
Autor:
Sena Azamat, Buse Buz-Yalug, Sukru Samet Dindar, Kubra Yilmaz Tan, Alpay Ozcan, Ozge Can, Ayca Ersen Danyeli, M. Necmettin Pamir, Alp Dincer, Koray Ozduman, Esin Ozturk-Isik
Publikováno v:
Diagnostics, Vol 14, Iss 7, p 748 (2024)
S100 protein expression levels and neurofibromatosis type 2 (NF-2) mutations result in different disease courses in meningiomas. This study aimed to investigate non-invasive biomarkers of NF-2 copy number loss and S100 protein expression in meningiom
Externí odkaz:
https://doaj.org/article/5f33fa928d3f4925a0c3ecc42d334ef0
Autor:
Lokman Cevik, Marilyn Vazquez Landrove, Mehmet Tahir Aslan, Vasilii Khammad, Francisco Jose Garagorry Guerra, Yolanda Cabello‐Izquierdo, Wesley Wang, Jing Zhao, Aline Paixao Becker, Catherine Czeisler, Anne Costa Rendeiro, Lucas Luis Sousa Véras, Maicon Fernando Zanon, Rui Manuel Reis, Marcus de Medeiros Matsushita, Koray Ozduman, M. Necmettin Pamir, Ayca Ersen Danyeli, Thomas Pearce, Michelle Felicella, Jennifer Eschbacher, Naomi Arakaki, Horacio Martinetto, Anil Parwani, Diana L. Thomas, José Javier Otero
Publikováno v:
Brain pathology (Zurich, Switzerland). 32(5)
Aims Resource-strained healthcare ecosystems often struggle with the adoption of the World Health Organization (WHO) recommendations for the classification of central nervous system (CNS) tumors. The generation of robust clinical diagnostic aids and