Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Koray, Kırımtay"'
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212518 (2019)
Microtubule severing, which is highly critical for the survival of both mitotic and post-mitotic cells, has to be precisely adjusted by regulating the expression levels of severing proteins, katanin and spastin. Even though severing mechanism is rela
Externí odkaz:
https://doaj.org/article/9b6ff0a2885a450e9cfae4f5672b6b3e
Autor:
Ece Selçuk, Koray Kırımtay, Benan Temizci, Şeyma Akarsu, Elif Everest, Mehmet Barış Baslo, Meltem Demirkıran, Zuhal Yapıcı, Arzu Karabay
Publikováno v:
Molecular Genetics and Genomics. 297:1141-1150
In this study, we aimed to determine the genetic basis of a Turkish family related to hereditary spastic paraplegia (HSP) by exome sequencing. HSP is a progressive neurodegenerative disorder and displays genetic and clinical heterogeneity. The major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517d87687a8951e44db62d599b8c1601
https://doi.org/10.1007/s00438-022-01910-5
https://doi.org/10.1007/s00438-022-01910-5
Background Kufor-Rakeb Syndrome (KRS) is an autosomal recessive disease characterized by Parkinsonism, pyramidal signs, dementia, and supranuclear gaze palsy. KRS is caused by mutations in ATP13A2 producing a transmembrane protein responsible for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835861da2e8bdcb4a1f80eb43f5b1ff4
https://aperta.ulakbim.gov.tr/record/237848
https://aperta.ulakbim.gov.tr/record/237848
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69423 (2013)
Katanin is an ATPase family member protein that participates in microtubule severing. It has heterodimeric structure consisting of 60 kDa (katanin-p60) and 80 kDa (katanin-p80) subunits encoded by KATNA1 and KATNB1 genes, respectively. Katanin-p60 ha
Externí odkaz:
https://doaj.org/article/8ce30aaaaf964267a8e2a263624130bf
Tumor suppressor protein p53, which functions in the cell cycle, apoptosis and neuronal differentiation via transcriptional regulations of target genes or interactions with several proteins, has been associated with neurite outgrowth through microtub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17795942dd8117720d156d7f08cc9bbc
https://aperta.ulakbim.gov.tr/record/3241
https://aperta.ulakbim.gov.tr/record/3241
Autor:
Betul Yuceturk, Bayram Yuksel, Alper Gezdirici, Asuman Koparir, Chad J. Creighton, Omer Faruk Karatas, Mahmut Şamil Sağıroğlu, Ece Selçuk, Ali Osman Bayrak, Mustafa Ozen, Adnan Yuksel, Arzu Karabay, Koray Kırımtay, Omer F. Gerdan
Publikováno v:
Human Molecular Genetics. 24:5378-5387
This work was supported by the Republic of Turkey Ministry of Development Infrastructure Grant (no. 2011K120020 to B.Y., A.O.B., O.F.G. and M.S.S.) and BILGEM-TUBITAK (the Scientific and Technological Research Council of Turkey) (grant no. T439000 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ac5749b860d26dbba73b1dc618a03b4
https://doi.org/10.1093/hmg/ddv261
https://doi.org/10.1093/hmg/ddv261
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212518 (2019)
PLoS ONE
PLoS ONE
Microtubule severing, which is highly critical for the survival of both mitotic and post-mitotic cells, has to be precisely adjusted by regulating the expression levels of severing proteins, katanin and spastin. Even though severing mechanism is rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12494a31e16866f407f833ce33b95a6d
https://doi.org/10.1371/journal.pone.0212518
https://doi.org/10.1371/journal.pone.0212518
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69423 (2013)
PLoS ONE
PLoS ONE
Katanin is an ATPase family member protein that participates in microtubule severing. It has heterodimeric structure consisting of 60 kDa (katanin-p60) and 80 kDa (katanin-p80) subunits encoded by KATNA1 and KATNB1 genes, respectively. Katanin-p60 ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c18832587688cfbf6a4255506074955c
http://europepmc.org/articles/PMC3722181?pdf=render
http://europepmc.org/articles/PMC3722181?pdf=render
Publikováno v:
Journal of Neurochemistry.
The most common cause of autosomal dominant hereditary spastic paraplegia, that is characterized with axonal degeneration in corticospinal tracts and posterior columns, is known to be caused by mutations in the SPG4 gene which encodes spastin, a micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dad45ccbff5c80218ac8cdf03fa87bd
https://doi.org/10.1111/j.1471-4159.2011.07243.x
https://doi.org/10.1111/j.1471-4159.2011.07243.x
Publikováno v:
Journal of neurochemistry. 117(4)
The most common cause of autosomal dominant hereditary spastic paraplegia, that is characterized with axonal degeneration in corticospinal tracts and posterior columns, is known to be caused by mutations in the SPG4 gene which encodes spastin, a micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e77117c0d0ce5851e8edc004365262df
https://pubmed.ncbi.nlm.nih.gov/21395583
https://pubmed.ncbi.nlm.nih.gov/21395583