Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Korabel, Nickolay"'
Transport of dense core vesicles (DCVs) in neurons is crucial for distributing molecules like neuropeptides and growth factors. We studied the experimental trajectories of dynein-driven directed movement of DCVs in the ALA neuron C. elegans over a du
Externí odkaz:
http://arxiv.org/abs/2407.18237
Extreme heterogeneity in the microrheology of lamellar surfactant gels analyzed with neural networks
Autor:
Moore, Owen Watts, Lewis, Conor, Ross, Thomas, Waigh, Thomas Andrew, Korabel, Nickolay, Mendoza, Cesar
The heterogeneity of the viscoelasticity of a lamellar gel network based on cetyl-trimethylammonium chloride (CTAC) and ceto-stearyl alcohol was studied using particle tracking microrheology. A recurrent neural network (RNN) architecture was used for
Externí odkaz:
http://arxiv.org/abs/2311.11941
Autor:
Waigh, Thomas A., Korabel, Nickolay
It is well established that a wide variety of phenomena in cellular and molecular biology involve anomalous transport e.g. the statistics for the motility of cells and molecules are fractional and do not conform to the archetypes of simple diffusion
Externí odkaz:
http://arxiv.org/abs/2310.09950
Autor:
Korabel, Nickolay1 (AUTHOR) nickolay.korabel@manchester.ac.uk, Warmenhoven, John W.2,3 (AUTHOR) john.warmenhoven@manchester.ac.uk, Henthorn, Nicholas T.2,3 (AUTHOR) nicholas.henthorn@manchester.ac.uk, Ingram, Samuel2,4 (AUTHOR) samuel.ingram@christie.nhs.uk, Fedotov, Sergei1 (AUTHOR), Heaven, Charlotte J.2,3 (AUTHOR) charlotte.heaven@manchester.ac.uk, Kirkby, Karen J.2,3 (AUTHOR) karen.kirkby@manchester.ac.uk, Taylor, Michael J.2,3 (AUTHOR) m.j.taylor@manchester.ac.uk, Merchant, Michael J.2,3 (AUTHOR) mikejmerchant@gmail.com
Publikováno v:
Entropy. Jun2024, Vol. 26 Issue 6, p502. 9p.
Autor:
Korabel, Nickolay, Clemente, Giuliana D., Han, Daniel, Feldman, Felix, Millard, Tom H., Waigh, Thomas Andrew
Drosophila melanogaster hemocytes are highly motile cells that are crucial for successful embryogenesis and have important roles in the organism's immunological response. Hemocyte motion was measured using selective plane illumination microscopy. Eve
Externí odkaz:
http://arxiv.org/abs/2109.03797
Autor:
Korabel, Nickolay, Han, Daniel, Taloni, Alessandro, Pagnini, Gianni, Fedotov, Sergei, Allan, Viki, Waigh, Thomas A.
Publikováno v:
Entropy 2021, 23, 958
Trajectories of endosomes inside living eukaryotic cells are highly heterogeneous in space and time and diffuse anomalously due to a combination of viscoelasticity, caging, aggregation and active transport. Some of the trajectories display switching
Externí odkaz:
http://arxiv.org/abs/2107.11553
Autor:
Korabel, Nickolay, Han, Daniel, Taloni, Alessandro, Pagnini, Gianni, Fedotov, Sergei, Allan, Viki, Waigh, Thomas Andrew
A major open problem in biophysics is to understand the highly heterogeneous transport of many structures inside living cells, such as endosomes. We find that mathematically it is described by spatio-temporal heterogeneous fractional Brownian motion
Externí odkaz:
http://arxiv.org/abs/2107.07760
Publikováno v:
Phys. Rev. E 103, 022132 (2021)
We introduce a persistent random walk model with finite velocity and self-reinforcing directionality, which explains how exponentially distributed runs self-organize into truncated L\'evy walks observed in active intracellular transport by Chen et. a
Externí odkaz:
http://arxiv.org/abs/2005.00498
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