Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Koorosh, Goodarzvand Chegini"'
Autor:
Morteza Ghazanfari Jajin, Raziyeh Abooshahab, Kourosh Hooshmand, Ali Moradi, Seyed Davar Siadat, Roghieh Mirzazadeh, Koorosh Goodarzvand Chegini, Mehdi Hedayati
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Medullary thyroid cancer (MTC) is a rare tumor that arises from parafollicular cells within the thyroid gland. The molecular mechanism underlying MTC has not yet been fully understood. Here, we aimed to perform plasma metabolomics profiling
Externí odkaz:
https://doaj.org/article/f462f105c16f497d8cb4b53c9cd7be38
Autor:
Fatemeh Taherkhani, Kamran Mousavi Hosseini, Sanaz Zebardast, Koorosh Goodarzvand Chegini, Nematollah Gheibi
Publikováno v:
Genetics and Molecular Biology, Vol 43, Iss 3 (2020)
Abstract Despite considerable advances, the treatment of pancreatic cancer (PC) still requires much effort. Unusual regulation of the Wnt and apoptotic signaling pathways is widespread in cancer incidence. For instance, the WIF1 (Wnt inhibitory facto
Externí odkaz:
https://doaj.org/article/489474c878f94a55866259131db7b273
Autor:
Koorosh Goodarzvand Chegini, Alireza Farasat, A Rahbarimehr, Nematollah Gheibi, SM Sadati, Parichehreh Yaghmaei
Publikováno v:
Journal of Applied Spectroscopy. 86:756-764
The interaction of nicotinic acid (Nic) and picolinic acid (Pic), as two pyridine carboxylic acids, with human serum albumin (HSA) as a major transport protein in the blood was investigated using UV-Vis, fluorimetry, circular dichroism (CD), and mole
Publikováno v:
The Protein Journal. 35:363-370
Calprotectin is member of the S-100 protein family with a wide plethora of intra-and extracellular functions. Anticancer activities, antimicrobial effects and being a qualified disease marker are among the compelling features of this protein to be us
Publikováno v:
Reports of biochemistrymolecular biology. 6(2)
Betatrophin is a member of the angiopoietin-like (ANGPTL) family that has been implicated in both triglyceride and glucose metabolism. The physiological functions and molecular targets of this protein remain largely unknown; hence, a purified availab
Autor:
Nematollah Gheibi, Hamideh Asghari, Fatemeh NematiNiko, Abbas Amini, Koorosh Goodarzvand Chegini
Publikováno v:
Biochimica et biophysica acta. Proteins and proteomics. 1865(3)
Tyrosinase is a determinant enzyme for modulating melanin production as its abnormal activity can result in an increased amount of melanin. Reduction of tyrosinase activity has been targeted for preventing and healing hyperpigmentation of skin, such
Autor:
Zahra Etemadifar, Koorosh Goodarzvand Chegini, Mohsen Ani, Mohammed Rabbani, Hamid Mirmohammad-Sadeghi, Fatemeh Moazen
Publikováno v:
Annals of Microbiology. 59:763-769
The aim of the present study was to express and evaluate a previously cloned lipase gene. In this study, the cloned gene was subcloned in the pET15bEscherichia coli BL21(DE3) expression system. The expression of the recombinant lipase was induced usi
Publikováno v:
International journal of biological macromolecules. 84
Recombinant pET 15b vectors containing the coding sequences S100A8 and S100A9 are expressed in Escherichia coli BL21 (DE3) and purified using Ni-NTA affinity chromatography. The structural changes of S100A8/A9 complex are analyzed upon interaction wi
Publikováno v:
Biotechnology and Health Sciences. 1
Background: S100A8 and S100A9 as two subunits of heterodimeric calprotectin are identified mainly in leukocytes and are involved in inflammatory processes and several cancerous pathogens. This study was performed in order to evaluate the interaction