Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Kook HW"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The waiting time to deceased-donor kidney transplantation (DDKT) is long in Asian countries. We investigated the impact of sensitization and ABO blood type (ABO) on DDKT opportunity using two Korean cohorts: a hospital cohort from two center
Externí odkaz:
https://doaj.org/article/71cdee2441f7454497bec7df3553f021
Autor:
Hyuk Huh, Yong Soo Kim, Wookyung Chung, Yong Lim Kim, Yaerim Kim, Seungyeup Han, Yeonsoon Jung, Ki Young Na, Kyu Beck Lee, Yun Kyu Oh, Hyeong Cheon Park, Seung Hyeok Han, Tae Hyun Yoo, Yeong Hoon Kim, Soo Wan Kim, Kang Wook Lee, Hayne Cho Park, Sung Gyun Kim, Hyunsuk Kim, Chang Hwa Lee, Kyongtae T. Bae, Kook Hwan Oh, Curie Ahn, Hyun Jin Ryu, Yong Chul Kim
Publikováno v:
Kidney Research and Clinical Practice, Vol 42, Iss 2, Pp 216-228 (2023)
Background Tolvaptan reduces height-adjusted total kidney volume (htTKV) and renal function decline in autosomal dominant polycystic kidney disease (ADPKD). This study was aimed at investigating the efficacy and safety of tolvaptan in Korean patients
Externí odkaz:
https://doaj.org/article/6097371022b54cc38061d29a236570c7
Autor:
Jang Hee Han, Yong Keon Kim, Hakhyun Kim, Jooyoung Lee, Myung Joon Oh, Sang Bum Kim, Minjee Kim, Kook Hwan Kim, Hyun Ju Yoon, Myung‐Shik Lee, John D. Minna, Michael A. White, Hyun Seok Kim
Publikováno v:
Cancer Communications, Vol 42, Iss 8, Pp 716-749 (2022)
Abstract Background Autophagy is elevated in metastatic tumors and is often associated with active epithelial‐to‐mesenchymal transition (EMT). However, the extent to which EMT is dependent on autophagy is largely unknown. This study aimed to iden
Externí odkaz:
https://doaj.org/article/870fa9cce81442b9a9dee6c2503ee3f6
Autor:
Tae Ryom Oh, Chana Myeong, Su Hyun Song, Hong Sang Choi, Sang Heon Suh, Chang Seong Kim, Eun Hui Bae, Wookyung Chung, Kyu Hun Choi, Kook Hwan Oh, Seong Kwon Ma, Soo Wan Kim
Publikováno v:
Kidney Research and Clinical Practice, Vol 41, Iss 2, Pp 200-208 (2022)
Background Osteoprotegerin is an important regulator of bone metabolism and vascular calcification. The association between serum osteoprotegerin level and chronic kidney disease (CKD) progression has not been elucidated. We investigated the prognost
Externí odkaz:
https://doaj.org/article/fdc46008080240c38d8171fb1a9e8162
Autor:
Seonhyang Jeong, Seul Gi Lee, Kook Hwan Kim, Xuguang Zhu, Woo Kyung Lee, Hwa Young Lee, Sunmi Park, Myung-Shik Lee, Sheue-Yann Cheng, Jandee Lee, Young Suk Jo
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
The thyroid gland plays an essential role in the regulation of body energy expenditure to maintain metabolic homeostasis. However, to date, there are no studies investigating the morphological and functional changes of the thyroid gland due to mitoch
Externí odkaz:
https://doaj.org/article/546902a8a26c42ce8591bfd01375a2ba
Autor:
Jinyoung Kim, Kihyoun Park, Min Jung Kim, Hyejin Lim, Kook Hwan Kim, Sun-Woo Kim, Eun-Seo Lee, Hyongbum (Henry) Kim, Sung Joo Kim, Kyu Yeon Hur, Jae Hyeon Kim, Jin Hee Ahn, Kun-Ho Yoon, Ji-Won Kim, Myung-Shik Lee
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Islet amyloid polypeptide (IAPP) deposition is associated with islet cell loss in diabetes. Here the authors show that a small molecule autophagy enhancer reduces IAPP accumulation in vitro, and also improves glucose tolerance in hIAPP + mice fed hig
Externí odkaz:
https://doaj.org/article/b7f9dbe17f134b678299722702178b09
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Growth differentiation factor 15 (GDF15) is an endocrine hormone belonging to the TGFβ superfamily member. GDF15 administration or GDF15 overexpression has been reported to have anti-obesity and anti-diabetic effects. Although non-alcoholic
Externí odkaz:
https://doaj.org/article/32eac4dcab774f319256f97ced562f95
Autor:
Hyejin Lim, Yu-Mi Lim, Kook Hwan Kim, Young Eui Jeon, Kihyoun Park, Jinyoung Kim, Hui-Yun Hwang, Dong Jin Lee, Haushabhau Pagire, Ho Jeong Kwon, Jin Hee Ahn, Myung-Shik Lee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Autophagy plays an important role in metabolic functions and increased autophagic activity may be beneficial for metabolic disorders. Here the authors screen a chemical library for enhancer of autophagic flux and identify small molecules that improve
Externí odkaz:
https://doaj.org/article/b5027a9d500c443aa7ee8732532b7ad0
Autor:
KyeongJin Kim, Kook Hwan Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7, p 2296 (2020)
Nonalcoholic steatohepatitis (NASH) is defined as a progressive form of nonalcoholic fatty liver disease (NAFLD) and is a common chronic liver disease that causes significant worldwide morbidity and mortality, and has no approved pharmacotherapy. Nev
Externí odkaz:
https://doaj.org/article/e640498d39014c9a841afe482046768c
Autor:
Kook Hwan Kim, Myung-Shik Lee
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Non-alcoholic fatty liver disease (NAFLD) is an emerging global health problem and a potential risk factor for type 2 diabetes, cardiovascular disease, and chronic kidney disease. Nonalcoholic steatohepatitis (NASH), an advanced form of NAFLD, is a p
Externí odkaz:
https://doaj.org/article/6b09f70d7008451eaec74c2bd2ba8025