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Vital and dispensable roles of Plasmodium multidrug resistance transporters during blood- and mosquito-stage development.

Autor: Rijpma SR; Department of Pharmacology and Toxicology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands., van der Velden M; Department of Pharmacology and Toxicology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands., Annoura T; Department of Tropical Medicine, The Jikei University School of Medicine, Post code 105-8461 Nishi-shinbashi 3-25-8, Minato-ku, Tokyo, Japan., Matz JM; Department of Medical Microbiology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands., Kenthirapalan S; Parasitology Unit, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117, Berlin, Germany., Kooij TW; Department of Medical Microbiology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands.; Centre for Molecular and Biomolecular Informatics, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands., Matuschewski K; Parasitology Unit, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117, Berlin, Germany.; Institute of Biology, Humboldt University, 10117, Berlin, Germany., van Gemert GJ; Department of Medical Microbiology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands., van de Vegte-Bolmer M; Department of Medical Microbiology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands., Siebelink-Stoter R; Department of Medical Microbiology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands., Graumans W; Department of Medical Microbiology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands., Ramesar J; Leiden Malaria Research Group, Parasitology, Center of Infectious Diseases, Leiden University Medical Center (LUMC), Albinusdreef 2, 2333, ZA, Leiden, The Netherlands., Klop O; Leiden Malaria Research Group, Parasitology, Center of Infectious Diseases, Leiden University Medical Center (LUMC), Albinusdreef 2, 2333, ZA, Leiden, The Netherlands., Russel FG; Department of Pharmacology and Toxicology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands., Sauerwein RW; Department of Medical Microbiology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands., Janse CJ; Leiden Malaria Research Group, Parasitology, Center of Infectious Diseases, Leiden University Medical Center (LUMC), Albinusdreef 2, 2333, ZA, Leiden, The Netherlands., Franke-Fayard BM; Leiden Malaria Research Group, Parasitology, Center of Infectious Diseases, Leiden University Medical Center (LUMC), Albinusdreef 2, 2333, ZA, Leiden, The Netherlands., Koenderink JB; Department of Pharmacology and Toxicology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands.

Publikováno v: Molecular microbiology [Mol Microbiol] 2016 Jul; Vol. 101 (1), pp. 78-91. Date of Electronic Publication: 2016 May 23.

The Plasmodium berghei translocon of exported proteins reveals spatiotemporal dynamics of tubular extensions.

Autor: Matz JM; 1] Parasitology Unit, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117 Berlin, Germany [2] Institute of Biology, Humboldt University, 10117 Berlin, Germany [3] Department of Medical Microbiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands., Goosmann C; Microscopy Core Facility, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117 Berlin, Germany., Brinkmann V; Microscopy Core Facility, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117 Berlin, Germany., Grützke J; Parasitology Unit, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117 Berlin, Germany., Ingmundson A; Parasitology Unit, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117 Berlin, Germany., Matuschewski K; 1] Parasitology Unit, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117 Berlin, Germany [2] Institute of Biology, Humboldt University, 10117 Berlin, Germany., Kooij TW; 1] Parasitology Unit, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117 Berlin, Germany [2] Department of Medical Microbiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands [3] Centre for Molecular and Biomolecular Informatics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

Publikováno v: Scientific reports [Sci Rep] 2015 Jul 29; Vol. 5, pp. 12532. Date of Electronic Publication: 2015 Jul 29.

Chemical attenuation of Plasmodium in the liver modulates severe malaria disease progression.

Autor: Lewis MD; Centre for Infectious Diseases, Parasitology Unit, Heidelberg University Hospital, D 69120 Heidelberg, Germany; German Centre for Infection Research, D 69120 Heidelberg, Germany;, Behrends J; Core Facility Fluorescence Cytometry, Research Center Borstel, D 23845 Borstel, Germany;, Sá E Cunha C; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisbon, Portugal;, Mendes AM; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisbon, Portugal;, Lasitschka F; German Centre for Infection Research, D 69120 Heidelberg, Germany; Institute of Pathology, Heidelberg University Hospital, D 69120 Heidelberg, Germany;, Sattler JM; Centre for Infectious Diseases, Parasitology Unit, Heidelberg University Hospital, D 69120 Heidelberg, Germany;, Heiss K; Centre for Infectious Diseases, Parasitology Unit, Heidelberg University Hospital, D 69120 Heidelberg, Germany; MalVa GmbH, D 69121 Heidelberg, Germany;, Kooij TW; Department of Medical Microbiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, 6500 HB Nijmegen, the Netherlands; Centre for Molecular and Biomolecular Informatics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, 6500 HB Nijmegen, the Netherlands; and., Prudêncio M; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisbon, Portugal;, Bringmann G; Institute for Organic Chemistry, University of Würzburg, 97074 Würzburg, Germany., Frischknecht F; Centre for Infectious Diseases, Parasitology Unit, Heidelberg University Hospital, D 69120 Heidelberg, Germany;, Mueller AK; Centre for Infectious Diseases, Parasitology Unit, Heidelberg University Hospital, D 69120 Heidelberg, Germany; German Centre for Infection Research, D 69120 Heidelberg, Germany; ann-kristin.mueller@uni-heidelberg.de.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2015 May 15; Vol. 194 (10), pp. 4860-70. Date of Electronic Publication: 2015 Apr 10.

Genetic crosses and complementation reveal essential functions for the Plasmodium stage-specific actin2 in sporogonic development.

Autor: Andreadaki M; Institute of Molecular Biology and Biotechnology, FORTH, Heraklion, Greece; Department of Biology, University of Crete, Heraklion, Greece., Morgan RN, Deligianni E, Kooij TW, Santos JM, Spanos L, Matuschewski K, Louis C, Mair GR, Siden-Kiamos I

Publikováno v: Cellular microbiology [Cell Microbiol] 2014 May; Vol. 16 (5), pp. 751-67. Date of Electronic Publication: 2014 Feb 20.