Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Kooi‐Yeong Khaw"'
Autor:
Jian Sheng Loh, Wen Qi Mak, Li Kar Stella Tan, Chu Xin Ng, Hong Hao Chan, Shiau Hueh Yeow, Jhi Biau Foo, Yong Sze Ong, Chee Wun How, Kooi Yeong Khaw
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-53 (2024)
Abstract The human gastrointestinal tract is populated with a diverse microbial community. The vast genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every aspect of human biology, including health maintenance, de
Externí odkaz:
https://doaj.org/article/699402e597a844858e3779ff9c622ceb
Autor:
Kooi Yeong Khaw, Michael R. Whittaker, Sanjaya Kuruppu, Kok Gan Chan, Siew Hua Gan, Bey Hing Goh
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/39929611a38f40e2b54d0d7f0df4dfac
Publikováno v:
Pharmacological Research, Vol 181, Iss , Pp 106260- (2022)
Heat shock protein 90 (Hsp90) has evolved as a cancerous cell growth regulator by stabilising various oncogenic kinases. Upon the Hsp90 inhibition, the expression of its client proteins is downregulated and thus leads to denaturation of cellular prot
Externí odkaz:
https://doaj.org/article/f91cdad86bd94fb49abcab7cb727fcdf
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1433-1441 (2020)
Mangosteen is one of the best tasting tropical fruit widely cultivated in Southeast Asia. This study aimed to quantify xanthone content in different parts of Garcinia mangostana by LC-QTOF-MS and determine its influence on their cholinesterase inhibi
Externí odkaz:
https://doaj.org/article/98cfa401efa44c81ab9971ebc7664cfb
Autor:
Nelson Jeng-Yeou Chear, Tan Ai Fein Ching-Ga, Kooi-Yeong Khaw, Francisco León, Wen-Nee Tan, Siti R. Yusof, Christopher R. McCurdy, Vikneswaran Murugaiyah, Surash Ramanathan
Publikováno v:
Metabolites, Vol 13, Iss 3, p 390 (2023)
The Uncaria genus is notable for its therapeutic potential in treating age-related dementia, such as Alzheimer’s disease. A phytochemical study of the leaves of Malaysian Uncaria attenuata Korth., afforded an undescribed natural corynanthe-type oxi
Externí odkaz:
https://doaj.org/article/59206ecad3da457e9c9c0a6ce70310fb
Autor:
Swee Li Ng BPharm(Hons), Kooi-Yeong Khaw PhD, Yong Sze Ong PhD, Hui Poh Goh PhD, Nurolaini Kifli PhD, Siew Phooi Teh BSc(Hons), Long Chiau Ming PhD, Vijay Kotra PhD, Bey Hing Goh PhD
Publikováno v:
Journal of Evidence-Based Integrative Medicine, Vol 26 (2021)
The management of the global pandemic outbreak due to the coronavirus disease (COVID-19) has been challenging with no exact dedicated treatment nor established vaccines at the beginning of the pandemic. Nonetheless, the situation seems to be better c
Externí odkaz:
https://doaj.org/article/a2dcdcfbfe5640ac9494b2055b26d6f1
Autor:
Chee Kei Kong, Liang Ee Low, Wei Sheng Siew, Wei-Hsum Yap, Kooi-Yeong Khaw, Long Chiau Ming, Andrei Mocan, Bey-Hing Goh, Poh Hui Goh
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Snowdrop is an iconic early spring flowering plant of the genus Galanthus (Amaryllidaceae). Galanthus species (Galanthus spp.) are economically important plants as ornaments. Galanthus spp has gained significance scientific and commercial interest du
Externí odkaz:
https://doaj.org/article/b0ac2c0eabe74b79befba1c6550272f7
Publikováno v:
Phytomedicine Plus, Vol 1, Iss 1, Pp 100022- (2021)
Background: The Dillenia suffruticosa leaves have been used in African tribal herbal medicine to relieve inflammatory conditions and memory loss. However, little is known about the phytoconstituents and their potential against cholinergic dysfunction
Externí odkaz:
https://doaj.org/article/74478e9c522442f7adb958128a24cf3f
Autor:
Wen-Nee Tan, Kashvintha Nagarajan, Vuanghao Lim, Juzaili Azizi, Kooi-Yeong Khaw, Woei-Yenn Tong, Chean-Ring Leong, Nelson Jeng-Yeou Chear
Publikováno v:
Journal of Fungi, Vol 8, Iss 5, p 519 (2022)
Endophytic fungi are a promising source of bioactive metabolites with a wide range of pharmacological activities. In the present study, MS-based metabolomics was conducted to study the metabolomes variations of endophytic Diaporthe fraxini ED2 grown
Externí odkaz:
https://doaj.org/article/3a62008998974e759a9a24ddfab9e28b
Autor:
Sathiya Maran, Robson Ee, Siti Aisyah Faten, Choi Sy Bing, Kooi Yeong Khaw, Swee-Hua Erin Lim, Kok-Song Lai, Wan Pauzi Wan Ibrahim, Mohd Rizal Mohd Zain, Kok Gan Chan, Siew Hua Gan, Huay Lin Tan
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0230982 (2020)
Atrial septal defect (ASD) is one of the most common congenital heart defects diagnosed in children. Sarcomeric genes has been attributed to ASD and knockdown of MYH3 functionally homologues gene in chick models indicated abnormal atrial septal devel
Externí odkaz:
https://doaj.org/article/6e32a638af21485ea255f80e443e993f