Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Koo-Hyeon Ahn"'
Autor:
Hiromitsu Kawata, Hitoshi Yoshino, Haruhiko Sato, Nobuyuki Ishikura, Masateru Ohta, Etsuro Onuma, Takuya Shiraishi, Kyung-Yun Jung, Mitsuaki Nakamura, Masahiro Nagamuta, Kazutaka Tachibana, Toshito Nakagawa, Shinichi Arai, Koo-Hyeon Ahn
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:3159-3168
A series of 5,5-dimethylthiohydantoin derivatives were synthesized and evaluated for androgen receptor pure antagonistic activities for the treatment of hormone refractory prostate cancer. CH4933468 (32d) with a sulfonamide side chain not only exhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ba02e5f233be169acfa3c16fe8e8218
https://doi.org/10.1016/j.bmc.2010.03.036
https://doi.org/10.1016/j.bmc.2010.03.036
Autor:
Motohiro Kato, Masayuki Suzuki, Naoki Taka, Masayuki Ohmori, Hiroharu Matsuoka, Keisuke Yamamoto, Koo-Hyeon Ahn, Kazumi Morikawa, Sang-Yong Yeu, Marina Yamaguchi, Hitoshi Hagita, Sachiya Ikeda, Koji Takano, Koji Yamaguchi, Tsutomu Sato, Takamitsu Kobayashi, Kazuharu Ozawa, Masahiro Nishimoto, Kyoko Takami, Yoshihito Ohtake
Publikováno v:
Journal of medicinal chemistry. 55(17)
Inhibition of sodium glucose cotransporter 2 (SGLT2) has been proposed as a novel therapeutic approach to treat type 2 diabetes. In our efforts to discover novel inhibitors of SGLT2, we first generated a 3D pharmacophore model based on the superposit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a6fd1743cdadf86034d4628892b3d23
https://pubmed.ncbi.nlm.nih.gov/22889351
https://pubmed.ncbi.nlm.nih.gov/22889351