Does cytochrome 2D6 genotype affect the analgesic efficacy of codeine after ambulatory surgery? Prospective trial in 987 adults.

Autor: Poikola S; Department of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Perioperative and Intensive Care, Helsinki University Hospital, Helsinki, Finland., von Plato H; Department of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Perioperative and Intensive Care, Helsinki University Hospital, Helsinki, Finland., Harju J; Gastroenterological surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Kiiski JI; Department of Clinical Pharmacology, University of Helsinki and HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.; Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Mattila K; Terveystalo Hospital, Helsinki, Finland., Olkkola KT; Department of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Perioperative and Intensive Care, Helsinki University Hospital, Helsinki, Finland.; Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Niemi M; Department of Clinical Pharmacology, University of Helsinki and HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.; Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Kalso E; Department of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Perioperative and Intensive Care, Helsinki University Hospital, Helsinki, Finland.; Department of Pharmacology, University of Helsinki, Helsinki, Finland., Kontinen V; Department of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Perioperative and Intensive Care, Helsinki University Hospital, Helsinki, Finland.

Publikováno v: Acta anaesthesiologica Scandinavica [Acta Anaesthesiol Scand] 2025 Jan; Vol. 69 (1), pp. e14549.

Effect of pain on autonomic nervous system indices derived from photoplethysmography in healthy volunteers

Autor: Hamunen, K., Kontinen, V., Hakala, E., Talke, P., Paloheimo, M. ^†, Kalso, E.

Publikováno v: In British Journal of Anaesthesia May 2012 108(5):838-844

Risk-based targeting of adjuvant pregabalin treatment in laparoscopic cholecystectomy: a randomized, controlled trial.

Autor: von Plato H; Helsinki University Hospital, Jorvi Hospital, P. O. Box 800, 00029 HUS, Helsinki, Finland.; Division of Perioperative Care, Jorvi Hospital, Department of Anesthesiology and Intensive Care Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Mattila K; Division of Perioperative Care, Jorvi Hospital, Department of Anesthesiology and Intensive Care Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Poikola S; Division of Perioperative Care, Jorvi Hospital, Department of Anesthesiology and Intensive Care Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Löyttyniemi E; Department of Biostatistics, University of Turku, Turku, Finland., Hamunen K; Helsinki Pain Clinic, Division of Pain Medicine, Department of Anesthesiology and Intensive Care Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Kontinen V; Division of Perioperative Care, Jorvi Hospital, Department of Anesthesiology and Intensive Care Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Publikováno v: Scandinavian journal of pain [Scand J Pain] 2019 Apr 24; Vol. 19 (2), pp. 309-317.

Dexamethasone decreases oxycodone consumption following osteotomy of the first metatarsal bone: a randomized controlled trial in day surgery.

Autor: MATTILA, K.¹ kristiina.mattila@hus.fi, KONTINEN, V. K.², KALSO, E.², HYNYNEN, M. J.¹

Publikováno v: Acta Anaesthesiologica Scandinavica. Mar2010, Vol. 54 Issue 3, p268-276. 9p. 1 Diagram, 3 Charts, 2 Graphs.

Adverse effects of perioperative paracetamol, NSAIDs, glucocorticoids, gabapentinoids and their combinations: a topical review

Autor: Mathiesen, O, Wetterslev, J, Kontinen, V K, Pommergaard, H-C, Nikolajsen, L, Rosenberg, J, Hansen, M S, Hamunen, K, Kjer, J J, Dahl, J B

Publikováno v: Mathiesen, O, Wetterslev, J, Kontinen, V K, Pommergaard, H-C, Nikolajsen, L, Rosenberg, J, Hansen, M S, Hamunen, K, Kjer, J J, Dahl, J B & Scandinavian Postoperative Pain Alliance (ScaPAlli) 2014, ' Adverse effects of perioperative paracetamol, NSAIDs, glucocorticoids, gabapentinoids and their combinations: a topical review ', Acta Anaesthesiologica Scandinavica, vol. 58, no. 10, pp. 1182-98 . https://doi.org/10.1111/aas.12380

Post-operative pain affects millions of patients worldwide and the post-operative period has high rates of morbidity and mortality. Some of this morbidity may be related to analgesics. The aim of this review was to provide an update of current knowle

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