Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Konstanze Miehle"'
Autor:
Diana Branco Vieira, Jochen Antel, Triinu Peters, Konstanze Miehle, Michael Stumvoll, Johannes Hebebrand, Haiko Schlögl
Publikováno v:
Obesity Facts (2022)
Introduction: Lipodystrophy (LD) syndromes are rare heterogeneous disorders characterized by reduction or absence of subcutaneous fat, low or non-detectable leptin concentrations in blood and impaired hunger/satiety regulation. Metreleptin treatment
Externí odkaz:
https://doaj.org/article/fbc22be3ceb743669e2d4402fda8dff0
Autor:
Julia von Schnurbein, Claire Adams, Baris Akinci, Giovanni Ceccarini, Maria Rosaria D’Apice, Alessandra Gambineri, Raoul C. M. Hennekam, Isabelle Jeru, Giovanna Lattanzi, Konstanze Miehle, Gabriele Nagel, Giuseppe Novelli, Ferruccio Santini, Ermelinda Santos Silva, David B. Savage, Paolo Sbraccia, Jannik Schaaf, Ekaterina Sorkina, George Tanteles, Marie-Christine Vantyghem, Camille Vatier, Corinne Vigouroux, Elena Vorona, David Araújo-Vilar, Martin Wabitsch
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-11 (2020)
Abstract Background Lipodystrophy syndromes comprise a group of extremely rare and heterogeneous diseases characterized by a selective loss of adipose tissue in the absence of nutritional deprivation or catabolic state. Because of the rarity of each
Externí odkaz:
https://doaj.org/article/ad91856d129d4197a99f9320d48d27e9
Autor:
Jörn F. Ziegler, Chotima Böttcher, Marilena Letizia, Cansu Yerinde, Hao Wu, Inka Freise, Yasmina Rodriguez-Sillke, Ani K. Stoyanova, Martin E. Kreis, Patrick Asbach, Desiree Kunkel, Josef Priller, Ioannis Anagnostopoulos, Anja A. Kühl, Konstanze Miehle, Michael Stumvoll, Florian Tran, Broder Fredrich, Michael Forster, Andre Franke, Christian Bojarski, Rainer Glauben, Britt-Sabina Löscher, Britta Siegmund, Carl Weidinger
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The adipokine leptin modulates intestinal inflammation in mice. Here the authors describe a patient with inflammatory bowel disease and lipodystrophy, providing evidence that leptin aggravates intestinal inflammation with proinflammatory effects on l
Externí odkaz:
https://doaj.org/article/930d669ed7b944499b66502ad66aa5e6
Autor:
Annett Hoffmann, Thomas Ebert, Mohammed K. Hankir, Gesine Flehmig, Nora Klöting, Beate Jessnitzer, Ulrike Lössner, Michael Stumvoll, Matthias Blüher, Mathias Fasshauer, Anke Tönjes, Konstanze Miehle, Susan Kralisch
Publikováno v:
Nutrients, Vol 13, Iss 8, p 2499 (2021)
Lipodystrophy syndromes (LD) are a heterogeneous group of very rare congenital or acquired disorders characterized by a generalized or partial lack of adipose tissue. They are strongly associated with severe metabolic dysfunction due to ectopic fat a
Externí odkaz:
https://doaj.org/article/45b858fdba1d428cb8902a9a6d207901
Autor:
Susan Kralisch, Annett Hoffmann, Juliane Estrada-Kunz, Michael Stumvoll, Mathias Fasshauer, Anke Tönjes, Konstanze Miehle
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7214 (2020)
Objective. Similar to obesity, lipodystrophy (LD) causes adipose tissue dysfunction and severe metabolic complications. Growth differentiation factor 15 (GDF15) belongs to the transforming growth factor β superfamily and is dysregulated in metabolic
Externí odkaz:
https://doaj.org/article/c58170a4fed14a1894cb893ac8c5f930
Publikováno v:
Obesity Facts, Vol 6, Iss 1, Pp 86-88 (2013)
It has been hypothesized that insulin might mediate meal-related diurnal variation in vaspin serum concentrations. We therefore investigated whether insulin affects serum vaspin levels in humans. Vaspin serum concentrations were determined by ELISA i
Externí odkaz:
https://doaj.org/article/fdb0a1a90a35483c8291ee25be1678b9
Autor:
Haiko Schlögl, Lieneke Janssen, Mathias Fasshauer, Konstanze Miehle, Arno Villringer, Michael Stumvoll, Karsten Mueller
Publikováno v:
Journal of the Endocrine Society
Context Behaviorally, the most pronounced effects of leptin substitution in leptin deficiency are the hunger-decreasing and postprandial satiety-prolonging effects of the adipokine. Previously, with functional magnetic resonance imaging (MRI), we and
Autor:
Héléna Mosbah, Baris Akinci, David Araújo-Vilar, Juan Carrion Tudela, Giovanni Ceccarini, Philippe Collas, I. Sadaf Farooqi, Antía Fernández-Pombo, Isabelle Jéru, Fredrik Karpe, Kerstin Krause, Margherita Maffei, Konstanze Miehle, Elif Oral, Naca Perez de Tudela, Xavier Prieur, Justin Rochford, Rebecca Sanders, Ferruccio Santini, David B. Savage, Julia von Schnurbein, Robert Semple, Anna Stears, Ekaterina Sorkina, Marie-Christine Vantyghem, Camille Vatier, Antonio Vidal-Puig, Corinne Vigouroux, Martin Wabitsch
Lipodystrophy syndromes are rare diseases with defects in the development or maintenance of adipose tissue, frequently leading to severe metabolic complications. They may be genetic or acquired, with variable clinical forms, and are largely underdiag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec79bf834b34d4dc3e01f5fa2685aca
https://avesis.deu.edu.tr/publication/details/aebbc333-a001-483c-83c7-7616113b5515/oai
https://avesis.deu.edu.tr/publication/details/aebbc333-a001-483c-83c7-7616113b5515/oai
Autor:
Paulina Elena Stürzebecher, Susan Kralisch, Marie Ruth Schubert, Vanina Filipova, Annett Hoffmann, Fabiana Oliveira, Bilal N. Sheikh, Matthias Blüher, Alexander Kogel, Markus Scholz, Karoline Elizabeth Kokot, Stephan Erbe, Jasmin Marga Kneuer, Thomas Ebert, Mathias Fasshauer, Konstanze Miehle, Ulrich Laufs, Anke Tönjes, Jes-Niels Boeckel
Publikováno v:
Proc. Natl. Acad. Sci. U.S.A. 119:e2110374119 (2022)
Lipodystrophy syndromes (LDs) are characterized by loss of adipose tissue, metabolic complications such as dyslipidemia, insulin resistance, and fatty liver disease, as well as accelerated atherosclerosis. As a result of adipose tissue deficiency, th
Publikováno v:
Abstracts des Adipositas-Kongresses 2022 zur 38. Jahrestagung der Deutschen Adipositas Gesellschaft e.V. DAG.