Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Konstantinos Toskas"'
Autor:
Erik Södersten, Konstantinos Toskas, Vilma Rraklli, Katarina Tiklova, Åsa K. Björklund, Markus Ringnér, Thomas Perlmann, Johan Holmberg
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
The limited size of some neuronal types and their entangled environment renders it difficult to study their transcription regulation. Here the authors present a comparative analysis of histone modifications and transcription in dopaminergic and serot
Externí odkaz:
https://doaj.org/article/6df7c45a61984546bf5cda6b2f25f8ed
Autor:
Angelos Papaspyropoulos, Leanne Bradley, Asmita Thapa, Chuen Yan Leung, Konstantinos Toskas, Delia Koennig, Dafni-Eleftheria Pefani, Cinzia Raso, Claudia Grou, Garth Hamilton, Nikola Vlahov, Anna Grawenda, Syed Haider, Jagat Chauhan, Ludovico Buti, Alexander Kanapin, Xin Lu, Francesca Buffa, Grigory Dianov, Alex von Kriegsheim, David Matallanas, Anastasia Samsonova, Magdalena Zernicka-Goetz, Eric O’Neill
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
In development, the switch from pluripotency to differentiation is important but it is often unclear how it is regulated. Here, the authors show that the tumour suppressor RASSF1A mediates this switch by promoting YAP-p73 transcription, which in turn
Externí odkaz:
https://doaj.org/article/851da86c94cb4859a74e3f6c31088f3a
Autor:
Xiaofei Li, Elisa M. Floriddia, Konstantinos Toskas, Karl J.L. Fernandes, Nicolas Guérout, Fanie Barnabé-Heider
Publikováno v:
EBioMedicine, Vol 13, Iss C, Pp 55-65 (2016)
Stem cells have a high therapeutic potential for the treatment of spinal cord injury (SCI). We have shown previously that endogenous stem cell potential is confined to ependymal cells in the adult spinal cord which could be targeted for non-invasive
Externí odkaz:
https://doaj.org/article/4ba4de3471864dfa8201dcef2e9d846a
Autor:
Erik Södersten, Konstantinos Toskas, Vilma Rraklli, Katarina Tiklova, Åsa K. Björklund, Markus Ringnér, Thomas Perlmann, Johan Holmberg
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
In the originally published version of this Article, financial support was not fully acknowledged. The PDF and HTML versions of the Article have now been corrected to include support to Thomas Perlmann provided by Knut and Alice Wallenberg Foundation
Externí odkaz:
https://doaj.org/article/89cfe751352c4056992547d84031ebc5
Autor:
Konstantinos Toskas, Behzad Yaghmaeian-Salmani, Olga Skiteva, Wojciech Paslawski, Linda Gillberg, Vasiliki Skara, Irene Antoniou, Erik Södersten, Per Svenningsson, Karima Chergui, Markus Ringnér, Thomas Perlmann, Johan Holmberg
Publikováno v:
Science advances. 8(34)
How neurons in the CNS can maintain cellular identity over an entire lifespan remains largely unknown. Here we show that long-term maintenance of identity in differentiated dopaminergic and serotonergic neurons is critically reliant on the Polycomb r
Autor:
Angelos Papaspyropoulos, Andriani Angelopoulou, Ioanna Mourkioti, Aikaterini Polyzou, Daniela Pankova, Konstantinos Toskas, Simone Lanfredini, Anastasia A Pantazaki, Nefeli Lagopati, Athanassios Kotsinas, Konstantinos Evangelou, Efstathios Chronopoulos, Eric O’Neill, Vassilis Gorgoulis
Publikováno v:
EMBO Rep
RASSF1A promoter methylation has been correlated with tumor dedifferentiation and aggressive oncogenic behavior. Nevertheless, the underlying mechanism of RASSF1A‐dependent tumor dedifferentiation remains elusive. Here, we show that RASSF1A directl
Autor:
Johan Holmberg, Erik Södersten, Vilma Rraklli, Markus Ringnér, Katarina Tiklova, Åsa K. Björklund, Konstantinos Toskas, Thomas Perlmann
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications
Nature Communications
The brain is composed of hundreds of different neuronal subtypes, which largely retain their identity throughout the lifespan of the organism. The mechanisms governing this stability are not fully understood, partly due to the diversity and limited s
Autor:
Thomas Perlmann, Markus Ringnér, Johan Holmberg, Konstantinos Toskas, Katarina Tiklova, Åsa K. Björklund, Erik Södersten, Vilma Rraklli
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The brain is composed of hundreds of different neuronal subtypes, which largely retain their identity throughout the lifespan of the organism. The mechanisms governing this stability are not fully understood, partly due to the diversity and limited s
Autor:
Nicolas Guérout, Fanie Barnabé-Heider, Karl J.L. Fernandes, Elisa M. Floriddia, Konstantinos Toskas, Xiaofei Li
Publikováno v:
EBioMedicine
EBioMedicine, Vol 13, Iss C, Pp 55-65 (2016)
EBioMedicine, Elsevier, 2016, 13, pp.55-65. ⟨10.1016/j.ebiom.2016.10.035⟩
EBioMedicine, Vol 13, Iss C, Pp 55-65 (2016)
EBioMedicine, Elsevier, 2016, 13, pp.55-65. ⟨10.1016/j.ebiom.2016.10.035⟩
Stem cells have a high therapeutic potential for the treatment of spinal cord injury (SCI). We have shown previously that endogenous stem cell potential is confined to ependymal cells in the adult spinal cord which could be targeted for non-invasive
Autor:
Steve Lacroix, Karl J.L. Fernandes, Nicolas Vallières, Xiaofei Li, Nicolas Guérout, Anne Aumont, Fanie Barnabé-Heider, Chaima Chalfouh, Axel Honoré, Elisa M. Floriddia, Konstantinos Toskas
Publikováno v:
Experimental Cell Research
Experimental Cell Research, Elsevier, 2018, 368 (1), pp.84-100. ⟨10.1016/j.yexcr.2018.04.017⟩
Experimental Cell Research, Elsevier, 2018, 368 (1), pp.84-100. ⟨10.1016/j.yexcr.2018.04.017⟩
Development of the spinal cord requires dynamic and tightly controlled expression of numerous transcription factors. Forkhead Box protein J1 (FoxJ1) is a transcription factor involved in ciliogenesis and is specifically expressed in ependymal cells (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f5bb28157c9695737b0086e57cf78e1
https://hal.archives-ouvertes.fr/hal-02366098
https://hal.archives-ouvertes.fr/hal-02366098