Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Konstantinos Sousounis"'
Autor:
Konstantinos Sousounis, Donald M Bryant, Jose Martinez Fernandez, Samuel S Eddy, Stephanie L Tsai, Gregory C Gundberg, Jihee Han, Katharine Courtemanche, Michael Levin, Jessica L Whited
Publikováno v:
eLife, Vol 9 (2020)
How salamanders accomplish progenitor cell proliferation while faithfully maintaining genomic integrity and regenerative potential remains elusive. Here we found an innate DNA damage response mechanism that is evident during blastema proliferation (e
Externí odkaz:
https://doaj.org/article/e92586a6cf15483d87539483428919e5
Autor:
Rong Zhao, Stacy D. Grunke, Madhusudhanan M. Keralapurath, Michael J. Yetman, Alexander Lam, Tang-Cheng Lee, Konstantinos Sousounis, Yongying Jiang, Deborah A. Swing, Lino Tessarollo, Daoyun Ji, Joanna L. Jankowsky
Publikováno v:
Cell Reports, Vol 16, Iss 3, Pp 793-804 (2016)
The neural network of the temporal lobe is thought to provide a cognitive map of our surroundings. Functional analysis of this network has been hampered by coarse tools that often result in collateral damage to other circuits. We developed a chemogen
Externí odkaz:
https://doaj.org/article/3e04b15e05c74992a67a8fe47841b100
Publikováno v:
Methods in Molecular Biology ISBN: 9781071626580
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::791e0cbbfcb67f35c09f11c1ff4be0c0
https://doi.org/10.1007/978-1-0716-2659-7_22
https://doi.org/10.1007/978-1-0716-2659-7_22
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2562
Clustered regularly interspaced short palindromic repeats (CRISPR) is a powerful tool that enables editing of the axolotl genome. In this chapter, we will cover how to retrieve gene sequences, confirm annotation, design CRISPR targets, analyze indels
Publikováno v:
The International journal of developmental biology
Axolotls and other salamanders have the capacity to regenerate lost tissue after an amputation or injury. Growth and morphogenesis are coordinated within cell groups in many contexts by the interplay of transcriptional networks and biophysical proper
Autor:
Konstantinos Sousounis, Feng Qi, Manisha C Yadav, José Luis Millán, Fubito Toyama, Chikafumi Chiba, Yukiko Eguchi, Goro Eguchi, Panagiotis A Tsonis
Publikováno v:
eLife, Vol 4 (2015)
Newts have the ability to repeatedly regenerate their lens even during ageing. However, it is unclear whether this regeneration reflects an undisturbed genetic activity. To answer this question, we compared the transcriptomes of lenses, irises and ta
Externí odkaz:
https://doaj.org/article/5817a24e55474510857230fd26ef1a87
Autor:
Konstantinos Sousounis, Mario Looso, Nobuyasu Maki, Clifford J Ivester, Thomas Braun, Panagiotis A Tsonis
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61445 (2013)
Regeneration of the lens in newts is quite a unique process. The lens is removed in its entirety and regeneration ensues from the pigment epithelial cells of the dorsal iris via transdifferentiation. The same type of cells from the ventral iris are n
Externí odkaz:
https://doaj.org/article/dd305e157dea41b783aebc4ac52810df
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78054 (2013)
Coleoid cephalopods like squids have a camera-type eye similar to vertebrates. On the other hand, Nautilus (Nautiloids) has a pinhole eye that lacks lens and cornea. Since pygmy squid and Nautilus are closely related species they are excellent model
Externí odkaz:
https://doaj.org/article/bcd92e2c00a847099e15c53792c1ab6d
Autor:
Katharine Courtemanche, Jessica L. Whited, Jihee Han, Jose Martinez Fernandez, Donald M. Bryant, Michael Levin, Stephanie L. Tsai, Samuel S Eddy, Konstantinos Sousounis, Gregory C Gundberg
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
How salamanders accomplish progenitor cell proliferation while faithfully maintaining genomic integrity and regenerative potential remains elusive. Here we found an innate DNA damage response mechanism that is evident during blastema proliferation (e
Autor:
Samuel S Eddy, Jessica L. Whited, Donald M. Bryant, Gregory C Gundberg, Jose Martinez Fernandez, Katharine Courtemanche, Konstantinos Sousounis, Michael Levin, Jihee Han, Stephanie L. Tsai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b6b647371b2c02531c6feb23c3fba81
https://doi.org/10.7554/elife.51217.sa2
https://doi.org/10.7554/elife.51217.sa2