Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Konstantinos S Papadakos"'
Autor:
Veroniaina Hanitrarimalala, Izabela Bednarska, Takashi Murakami, Konstantinos S. Papadakos, Anna M. Blom
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-14 (2024)
Abstract Chemotherapy persists as the primary intervention for breast cancer, with chemoresistance posing the principal obstacle to successful treatment. Herein, we show that cartilage oligomeric matrix protein (COMP) expression leads to increased ca
Externí odkaz:
https://doaj.org/article/59a80d2c8de9467982b53e4e9147be8b
Autor:
Gilar Gorji-Bahri, B. Madhu Krishna, Catharina Hagerling, Akira Orimo, Karin Jirström, Konstantinos S. Papadakos, Anna M. Blom
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Cartilage oligomeric matrix protein (COMP), an extracellular matrix glycoprotein, is vital in preserving cartilage integrity. Further, its overexpression is associated with the aggressiveness of several types of solid cancers. Thi
Externí odkaz:
https://doaj.org/article/70cd2d9352ca489783d89fb5d55c6172
Autor:
Konstantinos S Papadakos, Ioanna S Sougleri, Andreas F Mentis, Efstathios Hatziloukas, Dionyssios N Sgouras
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56291 (2013)
CagA protein contributes to pro-inflammatory responses during H. pylori infection, following its intracellular delivery to gastric epithelial cells. Here, we report for the first time in an isogenic background, on the subtle role of CagA phosphorylat
Externí odkaz:
https://doaj.org/article/340b7432385f491c87ea1bb462a7c2d0
Autor:
Anna M. Blom, Chrysostomi Gialeli, Catharina Hagerling, Jonna Berntsson, Karin Jirström, Konstantinos S. Papadakos
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionCartilage Oligomeric Matrix Protein (COMP) is an oncogenic protein that has been associated with a decrease in infiltrating T-cells in periampullary adenocarcinoma. This study aimed to investigate whether this is also the case for colorec
Externí odkaz:
https://doaj.org/article/196d7d38f38b48b7aa5ea66fe6f0bbaf
Autor:
Chrysostomi Gialeli, Emre Can Tuysuz, Johan Staaf, Safa Guleed, Veronika Paciorek, Matthias Mörgelin, Konstantinos S. Papadakos, Anna M. Blom
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/a5a425263be4480ca55c5c3797dd7348
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Background: Cartilage oligomeric matrix protein (COMP) is a pentameric cartilage protein also expressed in breast cancer tumors. A high expression of COMP evaluated by immunohistochemical staining is as an independent prognostic marker associated wit
Externí odkaz:
https://doaj.org/article/7895572e25fc43e7a522aed07911590f
Autor:
Konstantinos S. Papadakos, Alexander Ekström, Piotr Slipek, Eleni Skourti, Steven Reid, Kristian Pietras, Anna M. Blom
Publikováno v:
Journal of experimentalclinical cancer research : CR. 41(1)
Background Sushi domain-containing protein 4 (SUSD4) is a recently discovered protein with unknown cellular functions. We previously revealed that SUSD4 can act as complement inhibitor and as a potential tumor suppressor. Methods In a syngeneic mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654927d7d40a5bb77fb75b6da0827b94
https://pubmed.ncbi.nlm.nih.gov/36578014
https://pubmed.ncbi.nlm.nih.gov/36578014
Autor:
Konstantinos S. Papadakos, Sebastian Lundgren, Chrysostomi Gialeli, Patrick Micke, Artur Mezheyeuski, Jacob Elebro, Karin Jirström, Anna M. Blom
Publikováno v:
Oncoimmunology. 11(1)
Cartilage oligomeric matrix protein (COMP) is an emerging regulator of tumor progression. The aim of this study was to evaluate the expression of COMP in periampullary adenocarcinoma with respect to prognostic value for survival and relapse, levels o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa021911b1a1a5a620de71e2f281e729
https://pubmed.ncbi.nlm.nih.gov/35990519
https://pubmed.ncbi.nlm.nih.gov/35990519
Autor:
Blom, Konstantinos S. Papadakos, Catharina Hagerling, Lisa Rydén, Anna-Maria Larsson, Anna M.
Publikováno v:
Cancers; Volume 13; Issue 23; Pages: 5876
Cartilage oligomeric matrix protein (COMP) is a regulator of the extracellular matrix and is expressed primarily in the cartilage. Recently, COMP expression was also documented in breast cancer patients both in sera and tumor biopsies, in both of whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::a56d1cb9a3696089be335784d57f8893
Publikováno v:
Cancers
Cancers, Vol 13, Iss 5876, p 5876 (2021)
Cancers, Vol 13, Iss 5876, p 5876 (2021)
Simple Summary Cartilage oligomeric matrix protein (COMP) is an emerging independent prognostic marker for breast cancer patients. COMP expression by cancer cells affects their metabolism, metastases, and the abundance of cancer stem cell populations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f1e9b6448e616c830e0500aa3534d9d7
http://europepmc.org/articles/PMC8656813
http://europepmc.org/articles/PMC8656813