Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Konstantinos Kyparissoudis"'
Autor:
Florian Wiede, Sock Hui Chew, Catherine van Vliet, Ingrid J Poulton, Konstantinos Kyparissoudis, Tedjo Sasmono, Kim Loh, Michel L Tremblay, Dale I Godfrey, Natalie A Sims, Tony Tiganis
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36703 (2012)
Single nucleotide polymorphisms in the gene encoding the protein tyrosine phosphatase TCPTP (encoded by PTPN2) have been linked with the development of autoimmunity. Here we have used Cre/LoxP recombination to generate Ptpn2(ex2-/ex2-) mice with a gl
Externí odkaz:
https://doaj.org/article/51dc6f1cc935471aabaf1ba0355499e2
Autor:
Florian Wiede, Benjamin J. Shields, Sock Hui Chew Konstantinos Kyparissoudis, Catherine van Vliet, Sandra Galic, Michel L. Tremblay, Sarah M. Russell, Dale I. Godfrey, Tony Tiganis
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 20 (2023)
Externí odkaz:
https://doaj.org/article/4909791187f149db9c3967eac3a5b7b2
Autor:
Dale I. Godfrey, Stuart P. Berzins, Konstantinos Kyparissoudis, Tim J Cole, Douglas R. Liddicoat
Publikováno v:
Immunology & Cell Biology. 92:825-836
Glucocorticoids (GCs) are powerful inhibitors of inflammation and immunity. Although glucocorticoid-induced cell death (GICD) is an important part of GCs actions, the cell types and molecular mechanisms involved are not well understood. Untranslated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05180e7cda1bd0157e4cac49c5623dc4
https://doi.org/10.1038/icb.2014.57
https://doi.org/10.1038/icb.2014.57
Autor:
Raffi Gugasyan, Raelene J. Grumont, Konstantinos Kyparissoudis, Dale I. Godfrey, Philip N. Tsichlis, Steve Gerondakis, Sanda Stankovic, Ashish Banerjee
Publikováno v:
Immunology & Cell Biology. 89:294-303
The nuclear factor (NF)-κB signalling pathway is known to be critical for natural killer T (NKT) cell differentiation; however, the role of individual NF-κB transcription factors and the precise developmental stages that they control remain unclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca5bd0df4716ad8da1a1b517f3fe001
https://doi.org/10.1038/icb.2010.93
https://doi.org/10.1038/icb.2010.93
Autor:
Finlay W. McNab, Mark J. Smyth, Brent S. McKenzie, Stuart P. Berzins, Konstantinos Kyparissoudis, Jonathan M. Coquet, Lauren A. Pitt, Sumone Chakravarti, Dale I. Godfrey
Publikováno v:
Proceedings of the National Academy of Sciences. 105:11287-11292
NKT cell subsets can be divided based on CD4 and NK1.1 expression and tissue of origin, but the developmental and functional relationships between the different subsets still are poorly understood. A comprehensive study of 19 cytokines across differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b84ade02ddef7baf9f7f668403af05d4
https://doi.org/10.1073/pnas.0801631105
https://doi.org/10.1073/pnas.0801631105
Autor:
Mark J. Smyth, Jeremy Swann, Michele W.L. Teng, Yoshihiro Hayakawa, Dale I. Godfrey, Konstantinos Kyparissoudis
Publikováno v:
The Journal of Immunology. 176:1582-1587
CD4+CD25+ regulatory T cells (Treg) that suppress T cell-mediated immune responses may also regulate other arms of an effective immune response. In particular, in this study we show that Treg directly inhibit NKG2D-mediated NK cell cytotoxicity in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c899533c6f4edb598964494ca21403
https://doi.org/10.4049/jimmunol.176.3.1582
https://doi.org/10.4049/jimmunol.176.3.1582
Autor:
Mark J. Smyth, Dale I. Godfrey, Rachael Keating, Konstantinos Kyparissoudis, Francis R. Carbone, Ann L. Cornish
Publikováno v:
Immunology & Cell Biology. 84:13-19
NKT cells are a minor subset of T cells that have important roles in controlling immune responses in disease states including cancer, autoimmunity and pathogenic infections. In contrast to conventional T cells, NKT cells express an invariant TCR and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c52c0a6bc8fd22713b883158526191c4
https://doi.org/10.1111/j.1440-1711.2005.01396.x
https://doi.org/10.1111/j.1440-1711.2005.01396.x
Autor:
Jonathan M. Coquet, Mark J. Smyth, Konstantinos Kyparissoudis, Nadine Y. Crowe, Dale I. Godfrey, Rachael Keating, Stuart P. Berzins, Daniel G. Pellicci, Yoshihiro Hayakawa
Publikováno v:
The Journal of Experimental Medicine
Karolinska Institutet
Karolinska Institutet
We showed previously that NKT cell–deficient TCR Jα18−/− mice are more susceptible to methylcholanthrene (MCA)-induced sarcomas, and that normal tumor surveillance can be restored by adoptive transfer of WT liver-derived NKT cells. Liver-deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0360d7eec0422dddf258243d6087de74
https://doi.org/10.1084/jem.20050953
https://doi.org/10.1084/jem.20050953
Autor:
Kirsten J. L. Hammond, Dale I. Godfrey, Jonathan M. Coquet, Stephen J. Turner, Mark J. Smyth, Konstantinos Kyparissoudis, Rachael Keating, Stuart P. Berzins, Daniel G. Pellicci, Andrew G. Brooks, Katherine Kedzierska
Publikováno v:
Karolinska Institutet
Scopus-Elsevier
Scopus-Elsevier
NKT cells are typically defined as CD1d-dependent T cells that carry an invariant TCR α-chain and produce high levels of cytokines. Traditionally, these cells were defined as NK1.1+ T cells, although only a few mouse strains express the NK1.1 molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a36e69cf281ca2850d5617650d0520
https://doi.org/10.4049/jimmunol.175.7.4416
https://doi.org/10.4049/jimmunol.175.7.4416
Autor:
Dale I. Godfrey, Kenneth Field, Konstantinos Kyparissoudis, Finlay W. McNab, Mark J. Smyth, Stuart P. Berzins, Daniel G. Pellicci
Publikováno v:
The Journal of Immunology. 175:3762-3768
After being positively selected on CD1d-expressing thymocytes, NKT cells undergo a series of developmental changes that can take place inside or outside the thymus. We asked whether CD1d continues to play a role in late-stage NKT cell development and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3b2cee90e0f0972428fa3b44c492642
https://doi.org/10.4049/jimmunol.175.6.3762
https://doi.org/10.4049/jimmunol.175.6.3762