Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Konstantinos Aliazis"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
During the past decade, there has been a revolution in cancer therapeutics by the emergence of antibody-based immunotherapies that modulate immune responses against tumors. These therapies have offered treatment options to patients who are no longer
Externí odkaz:
https://doaj.org/article/c90816625c944df2937525f21edba765
Autor:
Nurshariza Abdullah, Nafees Ahemad, Konstantinos Aliazis, Jasmine Elanie Khairat, Thong Chuan Lee, Siti Aisyah Abdul Ahmad, Nur Amelia Azreen Adnan, Nur Omar Macha, Sharifah Syed Hassan
Publikováno v:
Viruses, Vol 13, Iss 6, p 1021 (2021)
Alphavirus non-structural proteins 1–4 (nsP1, nsP2, nsP3, and nsP4) are known to be crucial for alphavirus RNA replication and translation. To date, nsP3 has been demonstrated to mediate many virus–host protein–protein interactions in several f
Externí odkaz:
https://doaj.org/article/8ef1cd1b6fcf4aedb53dcddf18697e5a
Autor:
Sasitorn Yenyuwadee, Konstantinos Aliazis, Qi Wang, Anthos Christofides, Rushil Shah, Nikolaos Patsoukis, Vassiliki A. Boussiotis
Publikováno v:
Seminars in Cancer Biology. 86:187-201
During the past decade there has been a revolution in cancer therapeutics by the emergence of antibody-based and cell-based immunotherapies that modulate immune responses against tumors. These new therapies have extended and improved the therapeutic
Autor:
Al Charest, Vassiliki A. Boussiotis, Roel G.W. Verhaak, Steven P. Gygi, Hemant Varma, Joon Yoon, Vicky A. Appleman, Frederick S. Varn, Christopher M. Rose, Shruti Rawal, Piyan Zhang, Tuoye Xu, Rinku Pal, Konstantinos Aliazis, Rushil Shah, Alan T. Yeo
supplementary figures & legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70022129900a397dd403b1e4e220bf3a
https://doi.org/10.1158/2326-6066.22736977.v1
https://doi.org/10.1158/2326-6066.22736977.v1
Autor:
Al Charest, Vassiliki A. Boussiotis, Roel G.W. Verhaak, Steven P. Gygi, Hemant Varma, Joon Yoon, Vicky A. Appleman, Frederick S. Varn, Christopher M. Rose, Shruti Rawal, Piyan Zhang, Tuoye Xu, Rinku Pal, Konstantinos Aliazis, Rushil Shah, Alan T. Yeo
The composition of the tumor immune microenvironment (TIME) is considered a key determinant of patients’ response to immunotherapy. The mechanisms underlying TIME formation and development over time are poorly understood. Glioblastoma (GBM) is a le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::543faa9205d3847638c4473786e3c891
https://doi.org/10.1158/2326-6066.c.6597334
https://doi.org/10.1158/2326-6066.c.6597334
Autor:
Al Charest, Vassiliki A. Boussiotis, Roel G.W. Verhaak, Steven P. Gygi, Hemant Varma, Joon Yoon, Vicky A. Appleman, Frederick S. Varn, Christopher M. Rose, Shruti Rawal, Piyan Zhang, Tuoye Xu, Rinku Pal, Konstantinos Aliazis, Rushil Shah, Alan T. Yeo
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a623268b28b605e25745907cdd3d1d06
https://doi.org/10.1158/2326-6066.22736980.v1
https://doi.org/10.1158/2326-6066.22736980.v1
Autor:
Alan T. Yeo, Rushil Shah, Konstantinos Aliazis, Rinku Pal, Tuoye Xu, Piyan Zhang, Shruti Rawal, Christopher M. Rose, Frederick S. Varn, Vicky A. Appleman, Joon Yoon, Hemant Varma, Steven P. Gygi, Roel G.W. Verhaak, Vassiliki A. Boussiotis, Al Charest
Publikováno v:
Yeo, A T, Shah, R, Aliazis, K, Pal, R, Xu, T, Zhang, P, Rawal, S, Rose, C M, Varn, F S, Appleman, V A, Yoon, J, Varma, H, Gygi, S P, Verhaak, R G W, Boussiotis, V A & Charest, A 2023, ' Driver Mutations Dictate the Immunologic Landscape and Response to Checkpoint Immunotherapy of Glioblastoma ', Cancer Immunology Research, vol. 11, no. 5, pp. 629-645 . https://doi.org/10.1158/2326-6066.CIR-22-0655
Cancer Immunology Research, 11(5), 629-645. American Association for Cancer Research Inc.
Cancer Immunology Research, 11(5), 629-645. American Association for Cancer Research Inc.
The composition of the tumor immune microenvironment (TIME) is considered a key determinant of patients’ response to immunotherapy. The mechanisms underlying TIME formation and development over time are poorly understood. Glioblastoma (GBM) is a le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6417b788e05ae4916b1d2a24ee5a1ea1
https://research.vumc.nl/en/publications/8e8c49cb-4b3e-468f-9b8a-b6372f23f01e
https://research.vumc.nl/en/publications/8e8c49cb-4b3e-468f-9b8a-b6372f23f01e
Autor:
Arzoo M Patel, Zania Stamataki, Patrick T F Kennedy, Benjamin G. Wiggins, Xiaoyan Li, Yuxin S. Liu, Scott P Davies, Laura J. Pallett, Upkar S. Gill, Amir Gander, Gideon M. Hirschfield, Brian R. Davidson, Konstantinos Aliazis, Tu Vinh Luong, Yuehua Huang, Oliver E. Amin, Mala K. Maini, Stephanie Kucykowicz, Gary M. Reynolds
Publikováno v:
Gut. 71:1399-1411
ObjectiveTissue-resident memory T cells (TRM) are vital immune sentinels that provide protective immunity. While hepatic CD8+ TRM have been well described, little is known about the location, phenotype and function of CD4+ TRM.DesignWe used multipara
Autor:
Anthos Christofides, Xanthi-Leda Katopodi, Carol Cao, Dimitra Karagkouni, Konstantinos Aliazis, Sasitorn Yenyuwadee, Rinku Pal, John Asara, Ioannis Vlachos, Nikolaos Patsoukis, Vassiliki A Boussiotis
Publikováno v:
Blood. 140:1403-1404
Autor:
Anthos Christofides, Xanthi-Lida Katopodi, Carol Cao, Dimitra Karagkouni, Konstantinos Aliazis, Sasitorn Yenyuwadee, Halil-Ibrahim Aksoylar, Rinku Pal, Mohamed A. A. Mahmoud, Laura Strauss, Natalia M. Tijaro-Ovalle, Louis Boon, John Asara, Ioannis S. Vlachos, Nikolaos Patsoukis, Vassiliki A. Boussiotis
Publikováno v:
Nature immunology. 24(1)
The inhibitory receptor PD-1 suppresses T cell activation by recruiting the phosphatase SHP-2. However, mice with a T-cell-specific deletion of SHP-2 do not have improved antitumor immunity. Here we showed that mice with conditional targeting of SHP-